Antibacterial gel containing iodine tincture, and preparation method thereof
A technology of gel and tincture of iodine, applied in the direction of medical preparations containing active ingredients, antibacterial drugs, antifungal agents, etc., can solve the problems of povidone-iodine light and heat instability, unfavorable wound healing, local stimulation of iodine, etc. , to avoid excessive iodine concentration, good healing environment, and reduce irritation
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0021] Measure 35L of pure water into a vacuum emulsifier, add 60L of 95% alcohol, stir, add 0.1kg of zinc gluconate and stir, add 0.5kg of hydroxyethyl cellulose after dissolving, heat to 35°C ~ 40°C, stir at a low speed for 3- 5 hours, high-speed emulsification for 5-20 minutes, then add 3 kg of hydroxypropyl chitosan (Qingdao Honghai Biotechnology Co., Ltd., pH 6-8, substitution degree ≥ 60%), stir for 2-3 hours at 35 ° C ~ 40 ° C, high-speed emulsification 10-30min to make the two evenly mixed. Let it stand for 5-7 hours to let it cool down to room temperature, then add 0.6L of iodine tincture solution (self-made iodine tincture solution, the mass ratio of iodine to potassium iodide is 2:1, and the volume percentage concentration of alcohol is 60%), high-speed emulsification for 10 minutes, Stir at low speed for 30min-60min, put it in a container, seal it away from light and let it stand for about 7 days to decolorize, and get iodine antibacterial gel A.
Embodiment 2
[0023] Measure 43L of pure water into a vacuum emulsifier, add 50L of 95% alcohol, stir, add 0.2kg of zinc acetate and stir, add 1kg of hydroxypropyl cellulose after dissolving, heat to 35°C-40°C, stir at low speed for 3-5 hours , high-speed emulsification for 5-20 minutes, then add carboxymethyl chitin (Qingdao Honghai Biotechnology Co., Ltd., pH 6-8, substitution degree ≥ 80%) 2kg, stir at 35°C-40°C for 2-3 hours, high-speed emulsification for 10-30min , to mix the two evenly. Let it stand for 5-7 hours to let it cool naturally to room temperature, then add 2L iodine tincture (self-made iodine tincture solution, the mass ratio of iodine to potassium iodide is 4:1, and the volume percentage concentration of alcohol is 50%), emulsify at high speed for 15 minutes, and stir at low speed 30min-60min, put it in a container, seal it away from light and let it stand for about 15 days to decolorize, and get iodine antibacterial gel B.
Embodiment 3
[0025] Measure 53L of pure water into a vacuum emulsifier, add 40L of 95% alcohol, stir, add 1kg of zinc acetate and stir, add 2kg of carboxymethyl hydroxyethyl cellulose after dissolving, heat to 35°C ~ 40°C, stir at a low speed for 3- 5 hours, emulsify at high speed for 5-20min, then add 2 kg of sulfonated chitosan (self-made, pH6~8, degree of substitution ≥60%), stir at 35°C~40°C for 2-3 hours, emulsify at high speed for 10-30min, make both are evenly mixed. Let it stand for 5-7 hours to let it cool down to room temperature, then add 5L iodine tincture (self-made iodine tincture solution, the mass ratio of iodine to potassium iodide is 5:1, and the volume percentage concentration of alcohol is 40%), emulsify at high speed for 20 minutes, and stir at low speed 30min-60min, put it in a container, seal it and let it stand for about 20 days to decolorize, and get iodine antibacterial gel C.
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com