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Target drug for treating thyroid cancer and applications thereof

A thyroid cancer, targeted therapy technology, applied in the field of medicine, to control the proliferation and metastasis of cancer cells, and promote the effect of lysis

Inactive Publication Date: 2018-01-16
湖南晓林生物科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Further research in the later period showed that compound aluminum sulfate injection has a certain therapeutic effect on bladder tumors, but in the following 30 years, no aluminum sulfate can be used to treat other tumors

Method used

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  • Target drug for treating thyroid cancer and applications thereof
  • Target drug for treating thyroid cancer and applications thereof
  • Target drug for treating thyroid cancer and applications thereof

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Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0051] Experimental data to confirm the chemical structure

[0052] The experiment was entrusted to the Experimental Animal Center of Hunan Province (Hunan Province Drug Safety Evaluation Research Center).

[0053] 1. Compound name, molecular formula and molecular weight

[0054] Chinese name: aluminum sulfate octadecahydrate (hereinafter referred to as aluminum sulfate)

[0055] Molecular formula: Al 2 (SO 4 ) 3 18H 2 O, molecular weight: 666.4.

[0056] 2. The method of confirming the chemical structure

[0057] 1. Moisture determination

[0058] 1.1 Test conditions:

[0059] Instrument: V-30 Cassette Moisture Analyzer

[0060] Method: "Chinese Pharmacopoeia" 2015 Edition Four General Rules 0832 Moisture Determination Method 1.

[0061] 1.2 Measurement results

[0062] Table 2, Moisture determination results in aluminum sulfate

[0063]

[0064]

[0065] 1.3. Analysis

[0066] According to the calculation of aluminum sulfate structure and water content, th...

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Abstract

The invention discloses a target drug for treating thyroid cancer and applications thereof. Through long term research, for the first time, the inventor finds that aluminum sulfate can recognize the normal tissues and cancer tissues of human body, can change the physiological features of cancer cells, can inhibit cancer cells from secreting multiple proteases, and inhibits the metabolism of mitochondria of cancer cells. The drug can treat cancers. The drug can be combined with the DNA of cancer cells to promote the DNA cleavage, glycoprotein on the cell surface can be rapidly astringed and agglomerated, the structure of proteins on the cell surface is effectively changed, the signal channel is obstructed, the cell microstructure is changed, the drug combines with succinodehydrogenase in cell mitochondria, the proliferation and migration of cancer cells are controlled effectively, and the cancer cell inhibition rate is as high as 99.8 to 99.9% or even 100%. The side effect of aluminum sulfate is small, the safety is high, the oral administration has the advantages of low dosage, rapid effect, and short treatment course; the tumor size can be reduced rapidly, the apoptosis is induced, the proliferation is inhibited, finally the cancer cells fall off in fragments, and the drug has an important meaning for thyroid cancer treatment.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a medicine for treating thyroid cancer and a preparation method thereof. Background technique [0002] As we all know, malignant tumor is a kind of frequently-occurring and common disease that seriously threatens human health. Together with viral diseases and senile diseases, it is called the three major challenges of modern medicine. Its pathogenesis has not been fully elucidated, and the treatment effect is not satisfactory. According to incomplete statistics, the global average annual expenditure on cancer research and development and treatment is not less than tens of billions, which brings huge losses to the country, society and individuals. [0003] Thyroid cancer is the most common malignant tumor in head and neck tumors, and its incidence has continued to increase rapidly since 2000. In 2009, the incidence of thyroid cancer increased nearly three times compared with 1975, from 4.9...

Claims

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Application Information

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IPC IPC(8): A61K33/06A61K9/19A61K9/08A61P35/00
CPCA61K33/06A61K9/0019A61K9/19A61P35/00
Inventor 谢丹
Owner 湖南晓林生物科技发展有限公司
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