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Making method of radix-codonopsis broken-wall decoction piece

A technology of broken wall decoction pieces and a production method, which is applied in the directions of medical preparations containing active ingredients, pharmaceutical formulations, plant raw materials, etc., can solve the problems of loss of active ingredients, easy moisture absorption, increase in specific surface area of ​​powder, etc. The effect of wall ratio, good particle shape and moderate tightness

Inactive Publication Date: 2017-08-08
天马(安徽)国药科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Codonopsis pilosula, its active ingredients include triterpenoids, phytosterols, choline nitrogen-containing compounds, a large amount of carbohydrates and volatile oils, etc., the traditional decoction method is easy to destroy its heat-sensitive components, on the other hand, decoction of active ingredients Incomplete, resulting in the loss of active ingredients
Preparation of Codonopsis Codonopsis Codonopsis Codonopsis Superfine Powder is conducive to improving the utilization rate of active ingredients, but at the same time, due to the increase of powder specific surface area, it has the disadvantages of easy moisture absorption, oxidation, deterioration, etc.

Method used

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Experimental program
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Effect test

Embodiment 1

[0017] Embodiment 1: the preparation method of Codonopsis Codonopsis broken wall decoction piece, comprises the following contents:

[0018] (1) Medicinal material treatment: Select 2.0kg of dried herbal pilosula dangshen decoction pieces after picking and washing, soak in 0.15kg of soaking liquid, heat up to 45°C, cook at constant temperature for 35 minutes, continue to heat up to 85°C, and cook at constant temperature for 18 minutes , and finally heated to boiling, boiled for 12 minutes, cooled to room temperature, and taken out the Codonopsis pilosula slices; the raw materials of the soaking liquid are composed of 60 parts by weight of rice wine, 13 fresh milk, 9 refined honey, 22 mulberry juice, and 3.5 parts by weight of Semen Plantaginis. , Fried Puhuang 3, Zhigancao 4.5, Pipa Leaf 3.5, Astragalus 1.5; Weigh Plantago Seed, Fried Puhuang, Zhigancao, Pipa Leaf and Astragalus in parts by weight, add water for decoction, and cook with low heat after the water boils Boil for ...

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PUM

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Abstract

The invention discloses a making method of a radix-codonopsis broken-wall decoction piece. The making method comprises the following contents of first soaking a radix-codonopsis medicinal material in a soaking solution, then oven-drying a radix-codonopsis decoction piece, and then crushing the radix-codonopsis decoction piece through a crusher with a 100-mesh sieve, so as to subsequently make medicinal-material coarse powder of 80 to 120 meshes; afterwards, subjecting the medicinal-material coarse powder to microwave oven-drying in sequence, grinding the medicinal-material coarse powder into ultrafine powder, afterwards, further carrying out granulation through an ethanol-water wetting method, carrying out extrusion molding at a certain rotational speed, and carrying out drying, thereby making the radix-codonopsis broken-wall decoction piece. The radix-codonopsis broken-wall decoction piece provided by the invention is first soaked by adopting the soaking solution; the nutritive value of radix codonopsis is improved; the primary processing is carried out; afterwards, the granulation is further carried out through the ethanol-water wetting method; the grain of the made radix-codonopsis broken-wall decoction piece is better in grain type; the tightness is moderate; the stability is high; the disintegration is good; meanwhile, in comparation with a conventional ultramicro wall breakage crushing method, the making method is used for greatly improving the wall breakage rate of the radix codonopsis; a nutrient substance is maximally maintained; the beneficial effects that the wall breakage rate is high and a nutritional ingredient is stored completely are achieved.

Description

technical field [0001] The invention relates to a preparation method of decoction pieces, in particular to a preparation method of Codonopsis pilosula broken wall decoction pieces. Background technique [0002] Most of the active ingredients in Chinese herbal medicines are distributed in the cells. Conventional decoction pieces can only release part of the active ingredients, and the utilization rate of active ingredients is 10-30%. However, using the wall-breaking crushing technology, such as crushing Chinese herbal medicine pieces to 300 mesh About 86.7% of the cell wall breaking rate will increase the dissolution of the active ingredients in the medicinal materials, greatly enhance its efficacy, and the utilization rate of the active ingredients will be above 90%, so as to reduce the amount of medicinal materials used and protect the medicinal materials resources. The quality of the drug increases efficacy. However, the current main ultrafine pulverization technology sti...

Claims

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Application Information

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IPC IPC(8): A61K36/344A61K35/20A61K35/644A61K36/605A61K36/68A61K36/88A61K36/484A61K36/73A61K36/481
Inventor 马绍桓苏玉增
Owner 天马(安徽)国药科技股份有限公司
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