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Preparation method of stagnation resolving and tranquilization granules

A technology for depressing and tranquilizing granules and raw materials, which is applied in pharmaceutical formulations, nervous system diseases, medical preparations containing active ingredients, etc. Efficiency, reduction of solvent consumption, effect of less solvent consumption

Inactive Publication Date: 2017-07-25
TONGHUA ZHENLIN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the drug was formulated early, and the process is not reasonable, which seriously wastes energy and pollutes the environment. How to further reduce energy waste, high efficiency and environmental protection is a new problem.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] The preparation method of Jieyu Anshen Granules is characterized in that the steps are as follows:

[0017] Recipe: 80 parts of bupleurum, 60 parts of jujube, 80 parts of Shichangpu, 60 parts of ginger pinellia, 60 parts of fried Atractylodes macrocephala, 200 parts of floating wheat, 80 parts of made polygala, 60 parts of roasted licorice, 80 parts of fried gardenia, 200 parts of lily , 80 parts of dannanxing, 80 parts of turmeric, 200 parts of dragon teeth, 100 parts of fried jujube kernels, 100 parts of poria cocos, and 60 parts of angelica.

[0018] The steps consist of:

[0019] Raw material pretreatment: Plant raw materials need to be pretreated, that is, use a pulverizer to crush the plant raw materials into powder, and pass through a 0.38mm×0.38mm aperture sieve for later use.

[0020] Soaking before extraction: Put the powdery plant raw materials into a container, add water to soak, the ratio of solid to liquid is 1:1-1:3, stir well, soak for 4-8 hours, so tha...

Embodiment 2

[0026] Jieyu Anshen Granules

[0027] Recipe: 80 parts of bupleurum, 60 parts of jujube, 80 parts of Shichangpu, 60 parts of ginger pinellia, 60 parts of fried Atractylodes macrocephala, 200 parts of floating wheat, 80 parts of made polygala, 60 parts of roasted licorice, 80 parts of fried gardenia, 200 parts of lily , 80 parts of dannanxing, 80 parts of turmeric, 200 parts of dragon teeth, 100 parts of fried jujube kernels, 100 parts of poria cocos, and 60 parts of angelica.

[0028]First of all, the raw materials are pretreated, soaked before extraction, put in plastic bags (or bottles) and pressurized to break the wall to release the pressure, and then soaked after ultra-high pressure treatment. The pretreatment is to use a pulverizer to pulverize the plant raw material into powder and sieve. Put it into a container, add water (or alcohol) to soak, fully soak the expanded plant material, put it into a plastic bag (or bottle), remove the air, and seal it tightly. Put the p...

experiment example 1

[0030] Extract hand rate comparison table

[0031] multifunctional extraction UHP extraction the first time 15.2% 18.9% the second time 15.5% 20.2% the third time 15.3% 19.4% average yield 15.33% 19.5%

[0032] It can be seen from the list that the present invention can increase the yield, with an average yield of 19.5% (15.33% in the prior art), thereby improving the curative effect.

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PUM

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Abstract

The invention relates to a preparation method of a traditional Chinese medicine, i.e., a preparation method of stagnation resolving and tranquilization granules. Raw materials in a recipe are preprocessed; soaking is performed before extraction; materials are charged into plastic bags; pressurization wall breaking processing is performed: a raw material plastic bag is put into an ultra-high-pressure pressurization cabin; equipment is started; a pressurization cabin door is closed; the pressurization pressure value is set to be 50 to 600 Mpa; the pressure maintaining time value is 3 to 10 minutes; pressure is relieved: after the set pressure maintaining time is reached, the pressure is fast relieved within 3 seconds, so that the pressure is 0Mpa; after the ultra-high pressure processing, soaking is performed: the plastic bag is taken out from an ultra-high-pressure processing cabin; the raw materials subjected to wall breaking are poured into a stainless steel barrel or a soaking box; the material-liquid ratio is (1 to 10) to (1 to 30); water is added for soaking for 6 to 8 hours to obtain soaking liquid; the materials are prepared into granules according to the process. Through experiments, the method has the advantages that the cost is reduced; the yield is improved; the average yield is 19.5 percent, so that the curative effect is improved.

Description

technical field [0001] The invention relates to a preparation method of traditional Chinese medicine, that is, a preparation method of Jieyu Anshen Granules. Background technique [0002] In the prior art, insomnia has become more and more common due to the rapid acceleration of the pace of life and the sudden increase of pressure. Insomnia, also known as sleep onset and maintenance disorder (DlMS), refers to the inability to fall asleep or maintain a sleep state, resulting in insufficient sleep. Jieyu Anshen Granules (Guoyao Zhunzi Z20093537), has the functions of soothing the liver and relieving depression, calming the nerves and calming the mind, and can be used for diseases caused by mental stimulation such as emotional discomfort, liver depression and qi stagnation. Prescription: Bupleurum 80g, Jujube 60g, Shichangpu 80g, Ginger Pinellia 60g, Stir-fried Atractylodes macrocephala 60g, Floating wheat 200g, Zhiyuanzhi 80g, Zhilicorice 60g, Stir-fried gardenia 80g, Lily 20...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/16A61P25/24A61P25/20A61K35/02
Inventor 王国强隋勇
Owner TONGHUA ZHENLIN PHARMA CO LTD
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