Attapulgite-polyacrylic acid nanocomposite gel with high adsorptivity and preparation method thereof

Abstract

The invention discloses attapulgite-polyacrylic acid nanocomposite gel with the high adsorptivity and a preparation method thereof. The attapulgite-polyacrylic acid nanocomposite gel is characterized by being prepared from, by weight, 2-4 parts of nano-zeolite powder, 5-10 parts of attapulgite, 1-2 parts of silicon dioxide, 15-20 parts of a hydrochloric acid solution, 30-40 parts of a zinc sulfate solution, an appropriate amount of absolute ethyl alcohol, 1-3 parts of nylon fibers, 2-5 parts of a silane coupling agent KH-570, 2-5 parts of a silane coupling agent KH-550, 2-3 parts of chitosan, 0.4-1 part of cerous nitrate, 5-10 parts of acrylic acid, an appropriate amount of nitrogen and an appropriate amount of distilled water. According to the attapulgite-polyacrylic acid nanocomposite gel with the high adsorptivity and the preparation method thereof, chitosan added in a cooperative mode is rich in amino groups, and therefore not only can the amino groups be provided to be grafted on attapulgite to participate in crosslinking to enhance the stability of the network structure of the gel, but also the carrier adsorption amount of carriers can be increased due to the fact that chitosan has the very good adsorptivity; by adding the nano-zeolite powder and the like in a cooperative mode, the advantages of being good in adsorption performance and high in strength are given to the material.

Description

technical field [0001] The invention relates to an attapulgite carrier and its preparation, in particular to an attapulgite / polyacrylic acid nanocomposite gel with strong adsorption and a preparation method thereof. Background technique [0002] Drug carrier release and targeting system can reduce drug degradation and loss, reduce side effects, and improve bioavailability, so more and more attention has been paid to its research. Due to its unique amphiphilic structure, polymer surfactants can self-assemble to form various forms of aggregates, such as micelles, microemulsions, gels, liquid crystals, vesicles, etc. These aggregates have the ability to entrap drug molecules and at the same time have good permeability to the membrane, which has become an important research field of drug carriers. Attapulgite is a hydrous-rich magnesium-aluminosilicate mineral with attapulgite as the main component and a special fibrous crystal structure. Due to its excellent adsorption, ion e...

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Problems solved by technology

[0003] In his master's thesis "Gel Phenomenon and Application of Attapulgite / Polymer Nanocomposites Prepared by In-Situ Polymerization", Zhu Longxiang prepared nanocomposite hydrogels using attapulgite and acrylic acid, but they are used as drug carriers. There are also problems of poor loading capacity, antibacterial properties, and slow-release properties