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Xingnaojing injection and preparation method thereof

A technology of Xingnaojing injection and distillate, which is applied in the direction of medical formulas, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of low solubility, easy discoloration and precipitation of medicinal liquids, and achieve improved quality and stability sexual effect

Inactive Publication Date: 2017-01-04
上海辰松新材料科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the solubility of the ingredients and the active ingredients of some drugs is small, and after a period of time, the liquid is prone to discoloration, turbidity and precipitation, which limits the production of such traditional Chinese medicine injections

Method used

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  • Xingnaojing injection and preparation method thereof
  • Xingnaojing injection and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Raw materials of Xinnaojing injection: musk 7.5g, turmeric 30g, gardenia 30g, borneol 1g, sodium chloride for injection 8g, stabilizer 0.3g, antioxidant 0.3g.

[0033] The preparation method of Xingnaojing injection comprises the following steps:

[0034] (1) Mix gardenia and turmeric, add 1500ml of purified water, soak at 60°C for 1.5 hours, distill and extract for 18 hours, and collect 1000ml of distillate (I);

[0035] (2) Add musk to the distillate (I), add 250ml of water for injection, soak at 60°C for 1.5 hours, carry out distillation and extraction for 18 hours, and collect 1000ml of distillate (II);

[0036] (3) Add the stabilizer and antioxidant to the distillate (II), then grind the borneol and add it to the distillate (II), stir to dissolve completely, and mix well;

[0037] (4) Add sodium chloride for injection, and refrigerate at 1°C for 18 hours to obtain a refrigerated solution;

[0038] (5) Take the refrigerated liquid, filter it with a 0.22 μm micropo...

Embodiment 2

[0042] It is basically the same as Example 1, except that the stabilizer is obtained by uniformly mixing mannitol and Tween 80 at a mass ratio of 1:1. Obtain the Xingnaojing injection of embodiment 2.

Embodiment 3

[0044] It is basically the same as Example 1, except that the stabilizer is obtained by uniformly mixing mannitol and glycerol at a mass ratio of 1:1. Obtain the Xingnaojing injection of embodiment 3.

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Abstract

The invention discloses a Xingnaojing injection and a preparation method thereof. The Xingnaojing injection is prepared from raw materials in parts by weight as follows: 7.5 parts of musk, 30 parts of turmeric root tuber, 30 parts of cape jasmine fruits, 1 part of borneol, 8 parts of sodium chloride for injection, 0.1-0.5 parts of a stabilizer and 0.1-1 part of an antioxidant. According to the Xingnaojing injection and the preparation method thereof, the stabilizer and the antioxidant are added to the preparation process of the injection, the quality stability of the Xingnaojing injection is improved, the stabilizer further has a solubilization function and increases content of effective ingredients in the Xingnaojing injection, and the prepared Xingnaojing injection has functions of clearing away heat and fire, cooling blood, eliminating toxins and inducing resuscitation, and can be used for treating epidemic encephalitis, hepatic coma, the symptom of heat entering construction-blood, the symptom of invasion of pericardium by heat, high fever, dysphoria, coma and delirium, deep red tongue, rapid pulse and the like.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to Xingnaojing injection and a preparation method thereof. Background technique [0002] The prescription of Xinnaojing is selected from "Angong Niuhuang San", a representative of traditional Chinese medical prescriptions, and the prescription quantity is: musk 7.5g, turmeric 30g, gardenia 30g, borneol 1g, in the prescription, musk is pungent and warm 1. Resuscitate and refresh the mind, it can clear up the disadvantages of the orifices, and open the stagnation of the meridians; Gardenia is bitter and cold, clears away heat and fire, cools the blood and detoxifies, and can help the musk to invigorate the blood and cool the blood; Opening all orifices and dispersing stagnant fire; turmeric is hard and cold, pungent and bitter, promoting qi and relieving stagnation, combined with borneol, fragrant and filthy, opening and closing the orifices, to stren...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/08A61K47/26A61K47/10A61K47/12A61K47/20A61P31/14A61P1/16A61P25/00A61K31/045A61K35/55
CPCA61K36/9066A61K9/0019A61K9/08A61K31/045A61K35/55A61K36/744A61K47/10A61K47/12A61K47/20A61K47/26
Inventor 刘世超
Owner 上海辰松新材料科技有限公司
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