Mannitol injection
A technology of injection and mannitol, which is applied in the fields of drug delivery, plant raw materials, cardiovascular system diseases, etc., can solve the problems of easy crystallization of mannitol injection, delayed rescue time for critically ill patients, and reduced concentration of mannitol liquid. , to achieve the effect of improving rapid cerebral hemorrhage and high intracranial pressure, reducing adverse reactions, and little vascular stimulation
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Embodiment 1
[0030] The raw materials are taken according to the following weight percentages: 12% of mannitol, 1.3% of jasmine flower extract, 0.8% of Sanqi extract, and water for injection is added to 100%; the mannitol, jasmine flower extract and Sanqi extract are dissolved in an appropriate amount of water for injection Add 0.5% W / V activated carbon for needles, heat to boil, filter; add the remaining amount of water for injection, mix well, filter, fill and seal, and sterilize at 110°C for 18 minutes.
[0031] The preparation method of above-mentioned jasmine flower extract is as follows:
[0032] 1) Weigh the jasmine flower, add 18 times the weight of the jasmine flower in an ethanol solution with a volume concentration of 60%, adjust the pressure to 180 MPa, and perform ultra-high pressure treatment for 2 minutes to obtain an ultra-high pressure treatment liquid;
[0033] 2) Ultrasonic extraction of the ultra-high pressure treatment solution at a frequency of 60 MHz and a temperatur...
Embodiment 2
[0042] The raw materials are taken according to the following weight percentages: 15% of mannitol, 1.1% of jasmine flower extract, 1.1% of Sanqi extract, and water for injection is added to 100%; the mannitol, jasmine flower extract and Sanqi extract are dissolved in an appropriate amount of water for injection Add 0.5% W / V activated carbon for needles, heat to boil, filter; add the remaining amount of water for injection, mix well, filter, fill and seal, and sterilize at 110°C for 18 minutes.
[0043] The preparation method of above-mentioned jasmine flower extract is as follows:
[0044] 1) Weigh the jasmine flower, add 16 times the weight of the jasmine flower in an ethanol solution with a volume concentration of 65%, adjust the pressure to 160 MPa, and perform ultra-high pressure treatment for 3 minutes to obtain an ultra-high pressure treatment liquid;
[0045] 2) Ultrasonic extraction of the ultra-high pressure treatment solution at a frequency of 50 MHz and a temperatur...
Embodiment 3
[0054]Get raw materials according to the following weight percentages: 17% of mannitol, 0.8% of jasmine flower extract, 1.3% of Sanqi extract, add water for injection to 100%; dissolve mannitol, jasmine flower extract and Sanqi extract in appropriate amount of water for injection Add 0.5% W / V activated carbon for needles, heat to boil, filter; add the remaining amount of water for injection, mix well, filter, fill and seal, and sterilize at 110°C for 18 minutes.
[0055] The preparation method of above-mentioned jasmine flower extract is as follows:
[0056] 1) Weigh the jasmine flower, add 15 times the weight of the jasmine flower in an ethanol solution with a volume concentration of 70%, adjust the pressure to 140 MPa, and perform ultra-high pressure treatment for 4 minutes to obtain an ultra-high pressure treatment solution;
[0057] 2) Ultrasonic extraction of the ultra-high pressure treatment solution at a frequency of 30 MHz and a temperature of 60° C. for 20 minutes to ...
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