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Body sample angiographic filler and preparation method thereof

An angiography and filler technology, which is applied in the field of cadaveric angiography filler and its preparation, can solve the problems of unquantified perfusion volume, easy to produce artificial artifacts, and large amount of lead oxide, so as to achieve rapid self-coagulation and improve Clinical diagnosis and treatment level, the effect of strong toughness

Inactive Publication Date: 2015-04-08
黄海龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in practice, it is found that the "gold standard" still has some deficiencies: (1) the amount of lead oxide is too large, which is prone to artificial artifacts; (2) the amount of gelatin used as a carrier is insufficient; (3) the amount of perfusion has not been quantified, and it is easy to overdo or insufficient

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] An angiography filler and its preparation method. The filler is composed of E-51 type epoxy resin, 2,4,6-tris(dimethylaminomethyl)phenol (DMP-30), polypropylene glycol diglycidyl It is composed of ether (D-1217), T-31 epoxy resin curing agent and zinc oxide.

[0024] 1 The angiography filler of the present invention is prepared in the following ratio:

[0025] E-51 type epoxy resin: 100ml

[0026] 2,4,6-Tris(dimethylaminomethyl)phenol (DMP-30): 1ml

[0027] Polypropylene glycol diglycidyl ether (D-1217): 19-20ml

[0028] T-31 epoxy resin curing agent: 24ml

[0029] Zinc oxide: 50-55g

[0030] 2 The specific operation of preparing the angiography filler of the present invention:

[0031] Use a plastic syringe to extract 100ml of E-51 type epoxy resin, polypropylene glycol diglycidyl ether (D-1217) 19-20ml, T-31 epoxy resin curing agent 24ml, 2,4,6-tris(dimethylamino) Pour 1ml of methyl)phenol (DMP-30) into a 400ml beaker, and add 50-55g of zinc oxide as a powdered metal oxide contr...

Embodiment 2

[0033] An angiography filler and its preparation method. The filler is composed of E-51 type epoxy resin, 2,4,6-tris(dimethylaminomethyl)phenol (DMP-30), polypropylene glycol diglycidol It is composed of ether (D-1217), T-31 epoxy resin curing agent, and titanium dioxide.

[0034] 1 The angiography filler of the present invention is prepared in the following ratio:

[0035] E-51 type epoxy resin: 100ml

[0036] 2,4,6-Tris(dimethylaminomethyl)phenol (DMP-30): 1ml

[0037] Polypropylene glycol diglycidyl ether (D-1217): 9-15ml

[0038] T-31 epoxy resin curing agent: 28ml

[0039] Titanium dioxide: 25-30g

[0040] 2 The specific operation of preparing the angiography filler of the present invention:

[0041] Use a plastic syringe to extract 100ml of E-51 epoxy resin, 9-15ml of polypropylene glycol diglycidyl ether (D-1217), 28ml of T-31 epoxy resin curing agent, 2,4,6-tris(dimethylamino) Pour 1ml of methyl)phenol (DMP-30) into a 400ml beaker, and add 25-30g of titanium dioxide as a powdered...

Embodiment 3

[0043] An angiography filler and its preparation method. The filler is composed of E-51 type epoxy resin, 2,4,6-tris(dimethylaminomethyl)phenol (DMP-30), polypropylene glycol diglycidyl It is composed of ether (D-1217), T-31 epoxy resin curing agent and cuprous oxide.

[0044] 1 The angiography filler of the present invention is prepared in the following ratio:

[0045] E-51 type epoxy resin: 100ml

[0046] 2,4,6-Tris(dimethylaminomethyl)phenol (DMP-30): 1ml

[0047] Polypropylene glycol diglycidyl ether (D-1217): 13-15ml

[0048] T-31 epoxy resin curing agent: 24ml

[0049] Cuprous oxide: 75-85g

[0050] 2 The specific operation of preparing the angiography filler of the present invention:

[0051] Use a plastic syringe to extract 100ml of E-51 type epoxy resin, 13-15ml of polypropylene glycol diglycidyl ether (D-1217), 24ml of T-31 epoxy resin curing agent, 2,4,6-tris(dimethylamino) Pour 1ml of methyl)phenol (DMP-30) into a 400ml beaker, and add 75-85g of the metal oxide powder contras...

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Abstract

The invention relates to an angiography technology and an anatomy and casting technology of a body sample and specifically discloses a body sample angiographic filler and a preparation method thereof. The filler consists of E-51 epoxy resin, 2,4,6-tri(dimethylamino methyl) phenol (DMP-30), polypropylene glycol diglycidyl ether (D-1217), a T-31 epoxy resin curing agent and a metal oxide powder contrast agent (zinc oxide, titanium dioxide, cuprous oxide and chromium sesquioxide). The angiographic filler disclosed by the invention is simple to prepare, easy to regulate in concentration and color and hard to decolorize, and has the characteristics of being rapid in automatic coagulation, small in percentage of contraction, high in toughness, low in cost and the like. CT reconstruction of blood vessel images of a human body sample or an animal body sample (or organ) have the advantages of being clear, full, continuous, free of fake shadows and burrs and the like.

Description

Technical field [0001] The invention relates to angiography technology and anatomical casting technology of cadaver specimens. technical background [0002] Since 1990, many countries have invested a lot of talents and financial resources in the "Visible Human (VH) Project", and have achieved gratifying breakthrough results. However, in the process of processing the VH data set, small blood vessels cannot be segmented. Even the powerful and technologically advanced Voxel-man researchers can only artificially simulate small blood vessels using the Tube Editor. In 2002, Chinese anatomists used a combination of angiography technology and anatomical casting technology to successfully reconstruct part of the human blood vessels from the "Chinese Digital Human (CDH)" data set for the first time in the world. (Digital Human, DH)" has made a significant contribution to the development. At present, gelatin-lead oxide angiography technology has become a routine method for vascular anatom...

Claims

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Application Information

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IPC IPC(8): C08L63/00C08K3/22
Inventor 黄海龙李力强龚达聪张灼荣梁昆陈淑婷陈倩怡吴湖广
Owner 黄海龙
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