Traditional Chinese medicine extract for removing cigarette and wine toxins as well as preparation method and application thereof

A technology of extracts and traditional Chinese medicines, which is applied in the field of extracts and preparations of traditional Chinese medicines for detoxification of tobacco and alcohol.

Active Publication Date: 2014-12-24
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Coriacea japonicus mainly contains alkaloids, flavonoids, saponins, anthraquinones and other components (Fu X., Wu S.W., Meng H.C., Li C. Isolation and antioxidant activity of polysaccharides purified from Abrus cantoniensis Hance.Modern Food Science and Technology .2013, 29(7): 1559-1564; Shi Haiming, Wen Jing, Tu Pengfei. Study on the Chemical Constituents of Phyllostachys japonicus. Chinese Herbal Medicine. 2006, 37(11): 1610-1613), up to now there is no P. Reports on Detoxification of Tobacco and Alcohol

Method used

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  • Traditional Chinese medicine extract for removing cigarette and wine toxins as well as preparation method and application thereof
  • Traditional Chinese medicine extract for removing cigarette and wine toxins as well as preparation method and application thereof
  • Traditional Chinese medicine extract for removing cigarette and wine toxins as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] 1. Preparation of Herbal Extracts

[0036] Take chicken bone grass and lotus leaves 27:9.5, wash them, soak them for 6 hours, put them into the extraction container and boil them three times, each time for 0.5 hours. The medicinal liquids extracted several times were combined and concentrated into an extract, and the extraction solvent methanol was added for alcohol precipitation. The supernatant after alcohol precipitation was concentrated and passed through an AB-8 macroporous resin column. The ratio of resin column diameter to height is 1:8, the adsorption rate is 3.2BV / h, the analytical flow rate is 1.6BV / h, the specific gravity of the sample solution is adjusted to 1.02~1.05, and 30-70% of the parts are collected, concentrated and dried under reduced pressure to obtain the extract.

[0037] 2. Determination of total flavonoid content

[0038] According to the "Chinese Pharmacopoeia" 2010 edition, an appendix VA spectrophotometric method was used to determine the c...

Embodiment 2

[0040] 1. Preparation of Chinese herbal extracts

[0041] Take chicken bone grass and lotus leaves 27:9.5, wash them, soak them for 24 hours, put them in the extraction container and boil them 5 times, each time for 3 hours. Combine the medicinal liquids extracted several times, concentrate them into extracts, add the extraction solvent ethanol for alcohol precipitation, concentrate the supernatant after alcohol precipitation, pass through D-101 macroporous resin column, collect 30-70% of the parts, and concentrate under reduced pressure Dry the extract.

[0042] 2. Determination of total flavonoid content

[0043] The content of total flavonoids was determined by spectrophotometry. Taking quercetin as the reference substance, the specific experimental method is the same as in Example 1, and the total flavonoid content is 35.0%.

Embodiment 3

[0045] 1. Preparation of Chinese herbal extracts

[0046] Take chicken bone grass and lotus leaves 27:9.5, wash them, soak them for 6-24 hours, put them into an extraction container, add water and boil them 4 times, each time for 2 hours. The medicinal liquid extracted several times is combined and concentrated into an extract. After standing the extract, add ethanol for alcohol precipitation, take the supernatant after alcohol precipitation, concentrate, pass through AB-8 macroporous resin column, collect 30-70% parts, concentrate and dry under reduced pressure to obtain the extract.

[0047] 2. Determination of total flavonoid content

[0048] The content of total flavonoids was determined by spectrophotometry. Taking quercetin as the reference substance, the specific experimental method is the same as in Example 1, and the total flavonoid content is 47.1%.

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PUM

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Abstract

The invention relates to a traditional Chinese medicine extract for removing cigarette and wine toxins. The traditional Chinese medicine extract is prepared from raw medicinal materials such as abrus cantoniensis hance and lotus leaf and is extracted from the abrus cantoniensis hance and lotus leaf according to a ratio of 27:9.5, and the main component of the traditional Chinese medicine extract is general flavone. The invention also relates to application of the traditional Chinese medicine extract in preparation of medicines or foods for treating and preventing cigarette and wine toxins. The pharmacological experiment proves that the traditional Chinese medicine extract disclosed by the invention can effectively prevent injury of cigarette and wine toxins to liver cells, is prepared into tablets, chewing gums and other oral dosage forms and can be convenient to carry and convenient to take.

Description

technical field [0001] The invention relates to a traditional Chinese medicine extract, in particular to a traditional Chinese medicine extract for detoxification of tobacco and alcohol, its preparation method and application. Background technique [0002] Every day, including women and children, are exposed to the hazards of passive smoking. Cigarettes contain more than 3,000 kinds of harmful chemicals and more than 30 kinds of carcinogens. Nearly one million people die of smoking-related diseases every year, especially cancer and lung cancer. Cigarette toxicity is closely related. In the process of smoking, whether it is passive smoking or active smoking, the water-soluble part of cigarette smoke is more likely to be dissolved and absorbed by the mucus on the surface of the alveoli, causing damage to various organ systems of the body. Therefore, in addition to smoking ban and less smoking, it is of great significance to actively look for drugs or food to detoxify. [000...

Claims

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Application Information

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IPC IPC(8): A61K36/62A61P39/02A23L1/29A23F3/34A23G4/12A61K36/48A23L33/00
Inventor 黄宝康郑承剑张乃丹秦路平张巧艳韩婷陈璐张小刚
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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