Water-soluble vitamin combination medicament

A technology for water-soluble vitamins and drugs, which is applied in drug combination, drug delivery, active ingredients of heterocyclic compounds, etc., and can solve problems such as unstable storage, inconvenient storage and transportation, and easy damage

Inactive Publication Date: 2014-03-26
吴赣英
View PDF3 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, water-soluble vitamin injections are not stable when stored in a greenhouse, and are easily damaged when exposed to external forces such as light, heat, water, and oxidation. This brings great inconvenience to storage and transportation, and also increases product storage costs and costs. transportation cost

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Water-soluble vitamin combination medicament
  • Water-soluble vitamin combination medicament
  • Water-soluble vitamin combination medicament

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A combination medicine of water-soluble vitamins of the present invention is made of the following medicinal ingredients in parts by weight:

[0024]

[0025]

[0026] The method for preparing the described clindamycin hydrochloride combination medicine, the steps are as follows:

[0027] (1) Take water for injection whose weight is 5-20 times of the weight of the water-soluble vitamin, and under stirring, dissolve the water-soluble vitamin, sodium glutamate, and reduced glutathione completely respectively to obtain the water-soluble vitamin solutions of combination drugs;

[0028] (2) the solution obtained by the ultrafiltration membrane ultrafiltration step (1) with a molecular weight cut-off of 8000D, the solution is then ultrafiltered by a membrane with a molecular weight cut-off of 1500D, and the medicinal solution obtained by the ultrafiltration is retained;

[0029] (3) The liquid medicine obtained in step (2) was steam sterilized at 121° C. for 20 minutes...

Embodiment 2

[0036] A combination medicine of water-soluble vitamins of the present invention is made of the following medicinal ingredients in parts by weight:

[0037]

[0038] The method for preparing the described clindamycin hydrochloride combination medicine, the steps are as follows:

[0039] (1) Take water for injection whose weight is 5-20 times of the weight of the water-soluble vitamin, and under stirring, dissolve the water-soluble vitamin, sodium glutamate, and reduced glutathione completely respectively to obtain the water-soluble vitamin solutions of combination drugs;

[0040] (2) the solution obtained by the ultrafiltration membrane ultrafiltration step (1) with a molecular weight cut-off of 8000D, the solution is then ultrafiltered by a membrane with a molecular weight cut-off of 1500D, and the medicinal solution obtained by the ultrafiltration is retained;

[0041] (3) The liquid medicine obtained in step (2) was steam sterilized at 121° C. for 20 minutes;

[0042] ...

Embodiment 3

[0048] A combination medicine of water-soluble vitamins of the present invention is made of the following medicinal ingredients in parts by weight:

[0049]

[0050]

[0051] The method for preparing the described clindamycin hydrochloride combination medicine, the steps are as follows:

[0052] (1) Take water for injection whose weight is 5-20 times of the weight of the water-soluble vitamin, and under stirring, dissolve the water-soluble vitamin, sodium glutamate, and reduced glutathione completely respectively to obtain the water-soluble vitamin solutions of combination drugs;

[0053] (2) the solution obtained by the ultrafiltration membrane ultrafiltration step (1) with a molecular weight cut-off of 8000D, the solution is then ultrafiltered by a membrane with a molecular weight cut-off of 1500D, and the medicinal solution obtained by the ultrafiltration is retained;

[0054] (3) The liquid medicine obtained in step (2) was steam sterilized at 121° C. for 20 minutes...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides a water-soluble vitamin combination medicament which is characterized by being prepared from the medical components in parts by weight: 2.0-4.0 parts of thiamine hydrochloride, 3.0-5.0 parts of riboflavin sodium phosphate, 3.5-7.0 parts of pyridoxine hydrochloride, 0.002-0.008 part of cobamamide, 100-150 parts of vitamin C sodium, 30-50 parts of nicotinamide, 0.3-0.7 part of folic acid, 0.04-0.08 part of biotin, 10-20 parts of sodium pantothenate, 30-80 parts of sodium glutamate, 0.02-0.04 part of reduced glutathione and 0.2-0.8 part ethylenediamine tetraacetic acid disodium. The invention also provides a preparation method for the combination medicament. All the aspects of safety, stability and treating effect of the water-soluble vitamin combination medicament disclosed by the invention are higher than those of the conventional water-soluble vitamin medicament prepared in the prior art.

Description

technical field [0001] The invention relates to a combination medicine of water-soluble vitamins and a preparation method thereof. technical background [0002] Water-soluble vitamins, a group of vitamins that can dissolve in water, including B vitamins and vitamin C, mainly vitamin B 1 (thiamine), B vitamins 2 (riboflavin), vitamin B 3 (niacin), vitamin B 5 (pantothenic acid) vitamin B 6 (Pyridoxine), Vitamin B 7 (biological acid) and vitamin C, etc., are micronutrients for maintaining normal physiological functions and material and energy metabolism of the human body. Essential for enzymes that catalyze the metabolism of carbohydrates, lipids, and proteins. Water-soluble vitamins are difficult to synthesize and store in the body and must be taken from outside. Especially for patients with vitamin deficiency caused by surgery, hepatitis, cancer, etc., it has therapeutic effects. At the same time, it can prevent myocardial infarction, indigestion, and decreased resist...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K38/06A61K9/08A61P1/00A61P1/08A61P1/12A61P1/16A61P1/14A61P9/10A61P7/00A61P37/04A61P3/02A61K31/51A61K31/525A61K31/4415A61K31/714A61K31/375A61K31/455A61K31/519A61K31/4188A61K31/197A61K31/198
Inventor 吴赣英
Owner 吴赣英
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap