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Sodium glucuronate composite medicine

A kind of technology of sodium glucuronate and medicine, applied in the field of sodium glucuronate combination medicine and preparation thereof

Active Publication Date: 2012-06-27
江西月兔医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the sodium glucuronate pharmaceutical preparation of prior art has allergic reaction

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The sodium glucuronate combination medicine provided by the invention is made of the following medicinal ingredients in parts by weight:

[0025] Sodium glucuronate 0.1

[0026] Reduced Glutathione 0.02

[0027] Edetate disodium 0.2

[0028] The present invention provides a method for preparing the above-mentioned combination medicine, the steps are as follows:

[0029] (1) Take the water for injection whose weight is 10-20 times of the weight of the sodium glucuronate, under stirring, dissolve the sodium glucuronate, reduced glutathione, and disodium edetate respectively completely to obtain A solution of sodium glucuronate combination drug;

[0030] (2) the medicinal solution obtained by the ultrafiltration membrane ultrafiltration step (1) with a molecular weight cut-off of 1500D, leaving the medicinal solution obtained by ultrafiltration;

[0031] (3) The liquid medicine obtained in step (2) was steam sterilized at 121° C. for 20 minutes;

[0032] (4) When the ...

Embodiment 2

[0046] The sodium glucuronate combination medicine provided by the invention is made of the following medicinal ingredients in parts by weight:

[0047] Sodium glucuronate 0.4

[0048] Reduced Glutathione 0.04

[0049] Edetate disodium 0.8

[0050] The present invention provides a method for preparing the above-mentioned combination medicine, the steps are as follows:

[0051] (1) Take the water for injection whose weight is 10-20 times of the weight of the sodium glucuronate, under stirring, dissolve the sodium glucuronate, reduced glutathione, and disodium edetate respectively completely to obtain A solution of sodium glucuronate composition;

[0052] (2) the medicinal solution obtained by the ultrafiltration membrane ultrafiltration step (1) with a molecular weight cut-off of 1500D, leaving the medicinal solution obtained by ultrafiltration;

[0053] (3) The liquid medicine obtained in step (2) was steam sterilized at 121° C. for 20 minutes;

[0054](4) When the steril...

Embodiment 3

[0068] The sodium glucuronate combination medicine provided by the invention is made of the following medicinal ingredients in parts by weight:

[0069] Sodium glucuronate 0.1

[0070] Reduced Glutathione 0.04

[0071] Edetate disodium 0.2

[0072] The present invention provides a method for preparing the above-mentioned combination medicine, the steps are as follows:

[0073] (1) Take the water for injection whose weight is 10-20 times of the weight of the sodium glucuronate, under stirring, dissolve the sodium glucuronate, reduced glutathione, and disodium edetate respectively completely to obtain A solution of sodium glucuronate combination drug;

[0074] (2) the medicinal solution obtained by the ultrafiltration membrane ultrafiltration step (1) with a molecular weight cut-off of 1500D, leaving the medicinal solution obtained by ultrafiltration;

[0075] (3) The liquid medicine obtained in step (2) was steam sterilized at 121° C. for 20 minutes;

[0076] (4) When the ...

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Abstract

The invention provides a sodium glucuronate composite medicine, which comprises the following components with the optimal pesticide effect in parts by weight: 0.1-0.4 part of sodium glucuronate, 0.02-0.04 part of reduced glutathione and 0.2-0.8 part of edetate disodium. The invention provides a method for preparing the composite medicine. The composite medicine is obviously superior to the corresponding medicine of the prior art in the curative effect and the safety.

Description

technical field [0001] The invention relates to a sodium glucuronate combined medicine and a preparation method thereof. Background technique [0002] Sodium glucuronate, also known as sodium glucuronate, has important physiological functions: first, it can combine with metabolites, poisons or drugs containing phenolic groups, hydroxyl groups, carboxyl groups and amino groups in the liver or intestines in the human body to form a non-toxic The glucuronic acid conjugates are excreted from the urine and are used for the treatment of acute and chronic hepatitis and liver cirrhosis, as well as for the treatment of food and drug poisoning; secondly, it can reduce the activity of liver amylase and prevent the decomposition of glycogen. Increase liver glycogen and reduce fat reserves; the third is the composition of human connective tissue and collagen, so it becomes a drug for treating arthritis and rheumatism. It is a medicine with great market prospect. But the sodium glucuron...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/06A61K9/19A61K9/08A61K9/00A61K9/12A61P1/16A61K31/7012A61K31/198
Inventor 邓学峰蔡海德
Owner 江西月兔医疗器械有限公司
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