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Multidirectional valve hydrocephalus shunt valve with antibacterial and anticoagulant functions, and preparation and application method thereof

A shunt tube and effusion technology, applied in the field of effusion shunt, to prevent infection and blockage, solve complications, and facilitate long-term implantation

Inactive Publication Date: 2013-04-03
SHANDONG BRANDEN MEDICAL DEVICE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Aiming at the various inconveniences that current shunt tubes bring to surgery, the purpose of the present invention is to provide a multi-directional valve effusion shunt tube with antibacterial and anticoagulant functions and its preparation method and use method, which mainly solve the problem in effusion shunt surgery. Antibacterial and anticoagulant problems

Method used

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  • Multidirectional valve hydrocephalus shunt valve with antibacterial and anticoagulant functions, and preparation and application method thereof
  • Multidirectional valve hydrocephalus shunt valve with antibacterial and anticoagulant functions, and preparation and application method thereof

Examples

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preparation example Construction

[0046] The preparation process of the present invention is as follows:

[0047] 1. Preparation of shunt tube

[0048] Grind the ends of the silicone hose round, and use numerical control equipment to shape the opening of the multi-directional valve at a distance of 0.5 to 2 cm from the closed round head at one end. The opening valve is a gap opened along the axial direction of the tube, and the number is 2 to 4. , the length is about 1cm, distributed evenly along the circumferential direction of the tube, every two adjacent gaps are staggered about 1±0.2cm in the axial direction of the tube. Open small holes on the side wall of the other end of the pipe, preferably uniform in size and evenly distributed in the circumferential direction of the pipe.

[0049] 2. Antibacterial treatment

[0050] Weigh a certain amount of rifampicin, and use chloroform to prepare a solution with a concentration of 1-4g / L as antibacterial liquid one; or weigh a certain amount of nitrofurazone, an...

Embodiment 1

[0061] Rifampicin-chloroform solution, concentration 4g / L.

[0062] Furacilin-dimethyl sulfoxide solution, concentration 1g / L.

[0063] Heparin sodium-water solution, concentration 50g / L.

[0064] 1. Soak the hydrocephalus shunt in 4g / L rifampicin-chloroform solution for 5 minutes, take it out and dry it in an oven at 60°C.

[0065] 2. Treat the tube obtained in step 1 with a 1 g / L nitrofurazone-dimethylsulfoxide solution in the same way.

[0066] 3. Put the tube obtained in step 2 in the plasma immersion ion implantation device. After vacuuming, inject hydrogen gas with a gas pressure of 5P; the radio frequency discharge power is 200W; the amplitude of the loaded pulse high-voltage power supply is 1kV, and the duty cycle 3%; the heating temperature is 20°C, and the treatment time is 0.1h.

[0067] 4. Soak the shunt tube obtained in step 3 in a 50 g / L heparin sodium-water solution at 20°C for 2 hours, then rinse it with purified water, and dry it at 30°C.

[0068] 5. Packe...

Embodiment 2

[0070] Prepare with reference to the steps of Example 1. Wherein, step 2 is omitted, that is, only 4 g / L rifampicin-chloroform solution is used for antibacterial drugs.

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Abstract

The invention discloses a multidirectional valve hydrocephalus shunt valve with antibacterial and anticoagulant functions, and preparation and an application method thereof, and belongs to the field of medical equipment. Two ends of a drainage tube are sealed through a silicone hose; a plurality of long seams are axially cut on the side wall at one end of the drainage tube, so as to form a valve type channel; and a hole is punched in the side wall at the other end of the drainage tube, which is served as a channel for allowing intracranial liquid to flow into the hydrocephalus shunt. At least one type of antibacterial drug permeates in the shunt valve body, so as to prevent wound from being infected; and meanwhile, anticoagulant drugs are connected with the surface of the tube wall in a surface grafting manner, so as to prevent blood corpuscle and protein in hydrocephalus from being adhered to the inner tube wall and causing lumen blockage. The shunt valve is used for the drainage of hydrocephalus from brain to other body cavities, the antibacterial and anticoagulant design can effectively prevent infection and vessel clogging in hydrocephalus shunt, the multidirectional valve design at the remote end can prevent liquid from flowing back, and the hydrocephalus shunt valve is multifunctional.

Description

technical field [0001] The invention relates to a hydrocephalus shunt technology, in particular to a multi-directional valve hydrocephalus shunt tube with antibacterial and anticoagulant functions and its preparation method and use method. Background technique [0002] Hydrocephalus is a common disease in neurosurgery. At present, the more effective method is still to treat it by means of surgery, and shunt surgery is one of the commonly used operations. Ventriculoperitoneal shunt is commonly used in current hydrocephalus shunt, and the shunt tube used is a simple silicone tube. At present, the limitations of ventriculo-peritoneal shunt are: 1. Blood cells and proteins in hydrocephalus are easy to adhere and coagulate on the tube wall, causing blockage of the shunt tube, which brings great inconvenience to the operation; 2. The brain drains to the abdominal cavity, and the shunt tube that needs to be implanted under the skin is too long, and the wound is bigger and easy to ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M25/14A61L29/16
CPCA61M27/006A61L29/00A61M2025/0056
Inventor 张海军郭海宏沈学红
Owner SHANDONG BRANDEN MEDICAL DEVICE
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