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Chinese medicinal composition for treating diarrhea as well as preparation method and application thereof

A composition and a technology for diarrhea are applied in the directions of drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., and can solve the problems of inability to treat diarrhea well, inconvenient use of enema, easy occurrence of stomach pain, nausea and the like, Achieve the effect of improving survival and quality of life, good social and economic benefits, and safe and stable drug efficacy

Inactive Publication Date: 2014-06-25
THE FIRST AFFILIATED HOSPITAL OF XINXIANG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine generally uses enemas or berberine, but enemas are inconvenient to use, and berberine is bitter and cold, which can easily injure the spleen and stomach, impair gastrointestinal function, and more likely to cause digestive system symptoms such as stomach pain and nausea, aggravating the condition, and the use of antibiotics is likely to cause resistance. The properties of medicines cannot treat diarrhea well, and the market is in urgent need of a traditional Chinese medicine preparation for treating both symptoms and root causes of diarrhea.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1: the preparation of capsule

[0023] According to the raw material ratio in Table 1 and the conventional method of capsule dosage form, it is prepared into capsules, and the specific methods are as follows:

[0024] Take 20g of cloves, 10g of woody incense, 20g of dried ginger, 14g of fennel, 10g of Huoxiang, 11g of Evodia rutaecarpa, 7g of magnolia officinalis, 7g of licorice, add 10 times the amount of water, soak for 0.5h, and extract the volatile oil by steam distillation , the extraction time is 8 hours, the obtained volatile oil is clathrated with beta-cyclodextrin, and the saturated aqueous solution method is used to continuously stir for 3 hours under the condition of 60 ° C. The stirring speed is 100 rpm, and the beta-cyclodextrin clathrate of the volatile oil is obtained. b. Filter out the medicinal liquid obtained after steam distillation in the above steps, and collect it in another device; add 8 times the amount of water to decoct the medicinal...

Embodiment 2

[0025] Embodiment 2: the preparation of granule

[0026] According to the ratio of raw materials in Table 1 and the conventional method of granule dosage form, it is prepared into granules, and the specific method is as follows:

[0027] Take 25g of cloves, 8g of woody incense, 30g of dried ginger, 12g of fennel, 12g of wrinkled wrinkle, 9g of Evodia rutaecarpa, 9g of Magnolia officinalis officinalis officinalis officinalis officinalis officinalis officinalis officinalis officinalis officinalis officinalis officinalis officinalis officinalis officinalis Officinalis Officinalis Officinalis Officinalis Magnolia officinalis 9g, 5g of licorice, add 10 times the amount of water, soak for 0.5h, extract volatile oil by steam distillation , the extraction time is 8 hours, the obtained volatile oil is clathrated with beta-cyclodextrin, and the saturated aqueous solution method is used to continuously stir for 3 hours under the condition of 60 ° C. The stirring speed is 100 rpm, and the ...

Embodiment 3

[0028] Embodiment 3: the preparation of tablet

[0029] Prepare by the raw material proportioning of table 1 and tablet dosage form conventional method, be prepared into tablet, concrete method is as follows:

[0030] Take 30g of cloves, 6g of woody incense, 40g of dried ginger, 10g of cumin, 14g of wrinkled wrinkle, 7g of Evodia rutaecarpa, 11g of magnolia officinalis, 3g of licorice, add 10 times the amount of water, soak for 0.5h, and extract the volatile oil by steam distillation , the extraction time is 8 hours, the obtained volatile oil is clathrated with beta-cyclodextrin, and the saturated aqueous solution method is used to continuously stir for 3 hours under the condition of 60 ° C. The stirring speed is 100 rpm, and the beta-cyclodextrin clathrate of the volatile oil is obtained. b. Filter out the medicinal liquid obtained after steam distillation in the above steps, and collect it in another device; add 8 times the amount of water to decoct the medicinal residue for...

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Abstract

The invention discloses a Chinese medicinal composition for treating diarrhea as well as a preparation method and application thereof. The Chinese medicinal composition is prepared from the following raw materials: syzygium aromaticum, elecampane, rhizoma zingiberis, common fennel, wrinkled gianthyssop herb, medcinal evodia fruit, officinal magnolia bark and liquoric root. The preparation method comprises the following steps of: performing steam distillation on the raw materials; extracting volatile oil from the raw materials; filtering out a liquid medicine obtained after the steam distillation; collecting the liquid medicine into another container; adding water of which the weight is eight times that of dregs of a decoction into the dregs to decoct for one hour; filtering out the liquid medicine; combining the liquid medicine obtained after the steam distillation with the liquid medicine obtained by decocting the dregs and the water for one hour; condensing the liquid medicine; performing alcohol precipitation and spray-drying; and adding auxiliary materials to prepare various preparations. The Chinese medicinal composition can be used for treating the diarrhea. The invention also discloses the application of the Chinese medicinal composition in preparation of a medicine for treating the diarrhea.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating diarrhea, a preparation method and application thereof. Background technique [0002] Diarrhea (diarrhea) is a common symptom, which refers to the frequency of defecation significantly exceeding the usual habit, thin fecal matter, increased water content, daily defecation volume exceeding 200g, or containing undigested food or pus, blood, and mucus. Diarrhea is often accompanied by symptoms such as urgency to defecate, anal discomfort, and incontinence. Diarrhea is divided into acute and chronic categories. The onset of acute diarrhea is sharp, and the course of the disease is within 2 to 3 weeks. Chronic diarrhea refers to recurrent diarrhea with a course of more than two months or an intermittent period within 2 to 4 weeks. [0003] Western medicine treatment generally adopts: (1) contr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61P1/12
Inventor 杨道坤杨玉新李向青王涛张昌强马丽娟
Owner THE FIRST AFFILIATED HOSPITAL OF XINXIANG MEDICAL UNIV
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