Preparation method of patrimia scabiosaefolia extract

Abstract

The invention discloses a preparation method of a patrimia scabiosaefolia extract. The preparation method comprises the steps of: pulverizing cleaned patrimia scabiosaefolia raw materials into coarse powder; preparing a liquid mixture of water and volatile oil by adopting a stream distillation method; separating the liquid mixture to obtain patrimia scabiosaefolia volatile oil; drying the raw material coarse powder and immersing with an ethanol solution; adding an ethanol solution the weight of which is 15 times of the weight of the raw material coarse powder for percolation; collecting the percolate, decompressing and concentrating, and recovering ethanol; and adding the extracted volatile oil, and uniformly mixing to obtain the patrimia scabiosaefolia extract. The preparation method disclosed by the invention optimizes the percolation process, the yield of the obtained patrimia scabiosaefolia extract is increased greatly, and the content and the transfer rate of oleanolic acid are increased effectively and obviously. The patrimia scabiosaefolia extract has obvious effect on tranquilizing central nerves.

Description

technical field [0001] The invention relates to the technical field of drugs for treating central nervous system, in particular to a method for preparing a preparation for central nervous system sedation extracted from the crude drug of Patrinia officinalis. Background technique [0002] With the rapid development of social economy and the improvement of people's living standards, social competition is also intensifying. The severe employment situation and increasing work pressure. People are prone to enter the "sub-health" state under such tense environmental pressure for a long time. Among them, the most obvious manifestation is neurasthenia or mental illness with insomnia as the main symptom. According to statistics, the incidence of insomnia in the Chinese population is about 30%. [0003] At present, there are many kinds of central nervous system sedative drugs for the treatment of insomnia. Western medicines mainly focus on benzodiazepines such as diazepam, barbiturate...

AI Technical Summary

Problems solved by technology

The applicant's first Paijiang Tablets with Huanghua Paijiang as the main ingredient was first included in the 1977 edition of "Chinese Pharmacopoeia", but limited to the conditions at that time, the prescription only pointed out under the preparation method of the Chinese Pharmacopoeia Using 60% ethanol as a solvent for percolation extraction, there is no clear process conditions such as immersion time, percolation speed and percolation liquid collection dose in the percolation process, so it cannot be used as a standard production process to guide the production of drugs, as an active ingredient The volatile oil is not all extracted

At the same time, in the "Pharmacopia Standards" of Paijiang Tablets produced, there are only three large categories of color reactions of plant ingredients that are not very specific, and the product cannot be qualitatively and quantitatively tested, making it difficult to guarantee the quality of the drug.

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