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Method for preparing stomach-regulating pills

A technology of Zhongdropping Pills and Liuhe, which is applied in the field of preparation of Liuhe Dingzhong Dropping Pills, can solve problems such as being unable to cope with foreign drug competition, failing to meet consumer needs, and affecting the development of traditional Chinese medicine, achieving no toxic and side effects and low content of active ingredients. Stable and large drug loading effect

Active Publication Date: 2011-01-19
陕西中药研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In foreign countries, there are generally more than ten dosage forms for an API, but in my country there are only two or three. Many drugs, especially traditional Chinese medicines, only have one dosage form, which obviously cannot meet the needs of consumers and cannot cope with the competition of foreign drugs in the Chinese market. , the controlled-release and sustained-release preparations of foreign-funded and joint-venture pharmaceutical companies have a great impact on corresponding domestic drugs such as cold medicines, which greatly affects the development of traditional Chinese medicine

Method used

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  • Method for preparing stomach-regulating pills
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  • Method for preparing stomach-regulating pills

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The preparation method of Liuhedingzhong dripping pills comprises the following steps:

[0027] 1) In terms of parts by mass, after mixing 1 part of patchouli and 1 part of perilla leaves, add 5 times the mass of water to soak for 0.5 h, then heat and distill to extract the volatile oil for 5 h, and collect the extracted volatile oil ;

[0028] The volatile oil extracted by heating distillation is specifically extracted on a multifunctional extractor. After heating distillation, the volatile oil is collected from the oil discharge pipe of the oil-water separator.

[0029] 2) In terms of parts by mass, after mixing 13 parts of malt, 13 parts of rice sprouts, 13 parts of Liushenqu and 3 parts of white lentils, add water 10 times its mass, heat to 50°C, and keep at constant temperature for 1 hour After filtering, let the filtrate stand for 24h, then discard the precipitate and collect the supernatant, and concentrate the collected supernatant under reduced pressure to a r...

Embodiment 2

[0035] The preparation method of Liuhedingzhong dripping pills comprises the following steps:

[0036] 1) In terms of parts by mass, after mixing 2 parts of patchouli and 2 parts of perilla leaves, add 6 times the mass of water and soak for 0.5h, then heat and distill to extract the volatile oil for 6h, and collect the extracted volatile oil ;

[0037] The volatile oil extracted by heating distillation is specifically extracted on a multifunctional extractor. After heating distillation, the volatile oil is collected from the oil discharge pipe of the oil-water separator.

[0038]2) In terms of parts by mass, after mixing 15 parts of malt, 15 parts of rice sprouts, 15 parts of Liushenqu and 4 parts of white lentils, add water 8 times its mass, heat to 60°C, and keep at constant temperature for 1 hour After filtering, let the filtrate stand for 24h, then discard the precipitate and collect the supernatant, and concentrate the collected supernatant under reduced pressure to a re...

Embodiment 3

[0044] The preparation method of Liuhedingzhong dripping pills comprises the following steps:

[0045] 1) In terms of parts by mass, mix 3 parts of patchouli and 3 parts of perilla leaves, add 6 times its mass in water and soak for 0.5h, then heat and distill to extract volatile oil for 6h, and collect the extracted volatile oil ;

[0046] The volatile oil extracted by heating distillation is specifically extracted on a multifunctional extractor. After heating distillation, the volatile oil is collected from the oil discharge pipe of the oil-water separator.

[0047] 2) In terms of parts by mass, after mixing 17 parts of malt, 17 parts of rice sprouts, 17 parts of Liushenqu and 5 parts of white lentils, add water 8 times its mass, heat to 60°C, and keep at constant temperature for 1 hour After filtering, let the filtrate stand for 36h, then discard the precipitate and collect the supernatant, and concentrate the collected supernatant under reduced pressure to a relative densi...

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Abstract

The invention discloses a method for preparing stomach-regulating pills, which comprises the following steps of: respectively performing volatile oil extraction, water temperature extraction and alcohol extraction on different medicinal materials in the stomach-regulating formula, extracting effective parts therein, and mixing to obtain an intermediate for preparing the pills; and mixing the intermediate and a substrate, dispersing into the substrate, and performing a pill forming process to obtain the stomach-regulating pills. In the pill preparing process, each extraction link and the forming process have controllable quality, the content of active ingredients is stable, the pill preparation is carried out after the medicament intermediate is mixed fully with the substrate, and the medicament active ingredients are highly dispersed, so the prepared pills have high medicament stability.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparation and relates to a preparation method of Liuhe Dingzhong dripping pills. Background technique [0002] Flu, commonly known as a cold, the most common symptoms are cold with wind-cold, cold with wind-heat, cold with external cold and internal heat and gastrointestinal type cold. Among them, gastrointestinal flu is the most common and multiple, with hundreds of millions of people suffering from this disease every year. Especially in recent years, the abnormal change of climate and the change of people's eating habits have made the incidence of this disease show a trend of rapid growth. Traditional Chinese medicine calls this disease cold stagnation. In addition to the common symptoms of a cold, it mainly manifests as abdominal distension and abdominal pain, vomiting and diarrhea, and lack of appetite. Wait. Treatment should be to dispel summer heat and dampness, eliminate foo...

Claims

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Application Information

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IPC IPC(8): A61K36/8998A61K9/20A61P1/00A61P31/00
Inventor 张丽军秦永刚朱爱华杨钧
Owner 陕西中药研究所
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