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Emplastrum for treating white-plus disease and preparation method thereof

A technology for plasters and white pulses, which is applied in the field of plasters for treating white veins and its preparation, and can solve the problems of long production cycle, unstable sources of raw materials and auxiliary materials, and complicated processes

Active Publication Date: 2010-05-12
GANSU CHEEZHENG TIBETAN MEDICINE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

According to the records of "Four Medical Codes" and "Jingzhu Materia Medica", combined with long-term practical experience, the Tibetan people use turmeric, nutmeg, nard pine, actinolite, licorice, kaempferen, musk, Tibetan fennel, pepper, and alkali flower as raw materials The produced Tibetan medicine Baimai ointment is trusted by the majority of patients for its remarkable quality and effect. However, the traditional preparation process of Tibetan medicine Baimai ointment is to mix all the raw medicinal materials into fine powders to make ointment. The process is complicated and the batch production cycle is long. The production process is unstable; the sources of raw materials and excipients are unstable, which is not conducive to industrial production; some drugs have poor penetration ability and low bioavailability, and the curative effect cannot be fully guaranteed, so it is not suitable to exert the curative effect of the drug; in addition, the product is not suitable for storage and is inconvenient to carry; The reason has greatly affected the curative effect and promotion of the product

Method used

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  • Emplastrum for treating white-plus disease and preparation method thereof
  • Emplastrum for treating white-plus disease and preparation method thereof
  • Emplastrum for treating white-plus disease and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0417] Embodiment 1: plaster of the present invention

[0418] Raw material composition:

[0419] 36.3g of turmeric, 12.1g of nutmeg, 19.4g of nard pine, 12.1g of actinolite, 17.0g of licorice, 0.17g of artificial musk, 24.2g of dried ginger, 31.5g of Tibetan fennel, 17.0g of Tibetan calamus, 12.1g of Chinese prickly ash, alkali flower 18.2g;

[0420] Excipient composition:

[0421] Carbomer 20g, Azone 110g, Glycerin 30g, Glycoaluminate 15g, Sodium Hydroxide 25g, Methylparaben 3.5g;

[0422] Preparation method:

[0423] ① Grind artificial musk into fine powder;

[0424] ② Pick turmeric, nutmeg, nard pine, actinolite, licorice, dried ginger, Tibetan fennel, Tibetan calamus, peppercorns and alkali flowers, and crush them into ultrafine powders with a particle size of 0.1-1 μm;

[0425] ③Completely mix the above-mentioned superfine powder with the above-mentioned artificial musk fine powder, carbomer, azone, glycerin, glycine aluminum acid, sodium hydroxide, methyl paraben, ...

Embodiment 2

[0426] Embodiment 2: plaster of the present invention

[0427] Raw material composition:

[0428] Turmeric 36.3g, Nutmeg 12.1g, Nardin 19.4g, Actinolite 12.1g, Licorice 17.0g, Musk 0.17g, Dried Ginger 24.2g, Tibetan Fennel 31.5g, Tibetan Calamus 17.0g, Zanthoxylum bungeanum 12.1g, Alkali flower 18.2 g;

[0429] Excipient composition:

[0430] Gelatin 550g, dimethyl sulfoxide 25g, polyethylene glycol 80g, aluminum hydroxide 28g, citric acid 62g, sodium benzoate 5g, water 50g;

[0431] Preparation method:

[0432] ① Grind musk into fine powder;

[0433] ② Pick turmeric, nutmeg, nard pine, actinolite, licorice, dried ginger, Tibetan fennel, Tibetan calamus, peppercorns and alkali flowers, and crush them into ultrafine powders with a particle size of 1-10 μm;

[0434] ③ Fully mix the above-mentioned superfine powder with the above-mentioned musk fine powder, gelatin, dimethyl sulfoxide, polyethylene glycol, aluminum hydroxide, citric acid, sodium benzoate and water, stir even...

Embodiment 3

[0435] Embodiment 3: plaster of the present invention

[0436] Raw material composition:

[0437] 36.3g of turmeric, 12.1g of nutmeg, 19.4g of nard pine, 12.1g of actinolite, 17.0g of licorice, 0.17g of artificial musk, 24.2g of dried ginger, 31.5g of Tibetan fennel, 17.0g of Tibetan calamus, 12.1g of Chinese prickly ash, alkali flower 18.2g;

[0438] Excipient composition:

[0439] Sodium polyacrylate 2000g, water 1800g;

[0440] Preparation method:

[0441] ① Grind artificial musk into fine powder;

[0442] ② Pick and clean turmeric, nutmeg, nard pine, actinolite, licorice, dried ginger, Tibetan fennel, Tibetan calamus, peppercorns and alkali flowers, and crush them into a medicinal powder with a particle size of 10-40 μm;

[0443] ③ fully mix the above-mentioned medicated powder with the above-mentioned artificial musk fine powder, sodium polyacrylate and water, stir evenly, apply, condense, cover with a lining film, cut, and pack to obtain the plaster of the present i...

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Abstract

The invention discloses emplastrum for treating white-plus disease and a preparation method thereof. The emplastrum is prepared by taking a formula of conventional Tibetan medicament white-plus unguent as a basic formula and modifying the formulation. Compared with the medicament manufactured by the prior art, the emplastrum has the advantages that: the process is stable; the quality is high and controllable; the curative effect can be guaranteed; and the medicament content measurement and active ingredient detection can be performed to ensure the quality of the conventional Tibetan medicament emplastrum. The emplastrum is prepared by modern advanced technology that retains the active ingredients of the medicament and greatly improves the content and ratio of the raw medicaments to offer a better curative effect; and meanwhile, the emplastrum solves the problem of absorption, has quicker response, prolonged the shelf life of the medicament, is convenient to use and carry and safe to use.

Description

field of invention [0001] The invention relates to a plaster and a preparation method thereof, in particular to a plaster for treating leukemia and a preparation method thereof. technical background [0002] Baimai Ointment is a classic Tibetan medicine prescription composed of Tibetan folk doctors based on the records of "Tibetan Medicine and Supplements" and "Four Medical Codes", combined with practical experience. Baimai Ointment was originally recorded in "Drug Standards Issued by the Ministry of Health" Page 310 of the first volume of Tibetan medicine in the 1995 edition. The prescription of Baimai ointment is: [0003] 150g turmeric, 50g nutmeg, 80g nard pine, 50g actinolite, 70g licorice, 0.7g artificial musk or musk, 100g kaempferen, 130g Tibetan fennel, 70g Tibetan calamus, 50g pepper, 75g alkali flower. [0004] Preparation method: the above eleven flavors, except artificial musk or musk which are ground into fine powder, the rest are ground into fine powder, sie...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/70A61K47/46A61K47/44A61K47/34A61P19/00A61P19/04A61P25/00A61K35/55A61K33/26A61K33/00A61K31/122A61K47/10A61K47/26
Inventor 张樱山陈丽娟张国霞李波
Owner GANSU CHEEZHENG TIBETAN MEDICINE CO LTD
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