Medicament carrying film capable of being absorbed by oral cavity and preparation method thereof

Abstract

The invention provides a medicament carrying film capable of being absorbed by an oral cavity, which is characterized in that: the medicament carrying film capable of being absorbed by the oral cavityis prepared from active components of a small dose of medicaments, a water-soluble high polymer material and a pharmaceutically acceptable pharmaceutic adjuvant, wherein the pharmaceutically acceptable pharmaceutic adjuvant may be one or more of a stabilizer, a colorant, a sweetener, a correctant, a freshener and an emulsifier. The medicament carrying film capable of being absorbed by the oral cavity can be quickly dissolved in the oral cavity; the small dose of medicaments are absorbed in a form of a nonionic medicament in the pH value environment of the oral cavity; and a considerable amount of medicaments enter general blood circulation through the oral cavity, a throat and esophageal mucosa and can quickly reach the maximum plasma concentration. The medicament carrying film capable ofbeing absorbed by the oral cavity cannot generate any irritation to oral mucosa and has the advantages of adjustable mouthfeel, fragrant smell, and cool, refreshing and sweet taste. The medicament carrying film not only can refresh breath but also can better exert general action. The medicament carrying film not only can improve the compliance of patients, but also can improve the bioavailabilityof certain medicaments.

Description

technical field [0001] The invention relates to the field of pharmaceutical preparations, in particular to an orally absorbable drug-loaded film and a preparation method thereof. Background technique [0002] Many patients, especially the elderly and children often have difficulty swallowing solid preparations. Although these patients can take liquid preparations, it is very inconvenient to measure the volume of the liquid preparation. Difficulty swallowing tablets and capsules in patients such as severe illness, nausea migraine, or reflex nausea and vomiting to common pharmaceutical preparations. The orally digestible medicated film has a pleasant taste and is precisely dosed because it is packaged in single doses. [0003] It is very difficult for mental patients, especially acute psychotic episodes such as schizophrenia, to take common pharmaceutical preparations. Because the oral digestible film dissolves quickly in the mouth, it is difficult for such patients to keep...

AI Technical Summary

Problems solved by technology

Although these patients can take liquid preparations, it is very inconvenient to measure the volume of the liquid preparation