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Chinese medicinal composition for treating insomnia and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition and preparation thereof, can solve the problems of no special effect, recurrence and the like, and achieve the effects of simple prescription, prolonging sleep time, and strengthening hypnotic effect

Inactive Publication Date: 2009-08-05
SHANGHAI JIANWU MEDICAMENT SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Modern medicine has no specific effect on insomnia. Western medicines are mostly maintained with anti-anxiety and sedative-hypnotic drugs. If the drug is stopped, the recurrence will be even more serious. After taking these drugs for a long time, the patient will have side effects such as headache, dizziness, nausea, gastrointestinal discomfort, and body weakness.

Method used

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  • Chinese medicinal composition for treating insomnia and preparation method thereof
  • Chinese medicinal composition for treating insomnia and preparation method thereof

Examples

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Effect test

Embodiment 1

[0026] The preparation of embodiment 1 crude drug powder

[0027] Wash Zijinlong, Shichangpu and Chuanxiong respectively, dry them in the air, chop them up, and pass through a 60-mesh sieve. Weigh three medicinal material powders according to the following weight ratio: 200g Zijinlong, 120g Shichangpu, and 40g Chuanxiong, and mix them evenly to obtain crude drug powder.

Embodiment 2

[0028] The preparation of embodiment 2 capsules

[0029] (1) Wash the three medicinal materials in the prescription respectively, dry them in the air, chop them up, and pass through a 60-mesh sieve.

[0030] (2) Weigh three medicinal material powders according to the following weight ratio: Zijinlong 200g, Shichangpu 120g, Chuanxiong 40g, add microcrystalline cellulose 30g, magnesium stearate 2g, and mix well.

[0031] (3) Put the above mixture powder into No. 0 capsules (about 0.4 g), 1000 capsules in total.

Embodiment 3

[0032] Example 3 Preparation of Active Ingredient Liquid

[0033] Take 100g Zijinlong, 50g Shichangpu, and 30g Chuanxiong, add water to decoct twice, each time add water 8 times the weight of the medicinal materials, decoct for 1 hour each time, and decoct at the boiling temperature of the solution. The secondary extracts are combined, filtered, and concentrated under reduced pressure to a concentrated solution with a relative density of 1.04, which is the active ingredient liquid of the present invention.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating insomnia, which is mainly prepared from the following raw material drugs in portion by weight: 5 to 15 portions of dactylicapnos root, 3 to 10 portions of grassleaf sweelflag rhizome, and 1 to 5 portions of Szechuan lovage rhizome. The invention also discloses a method for preparing crude drug powder, active component liquid medicine and dry extract powder of the traditional Chinese medicine composition. The traditional Chinese medicine composition has a simple formulation, and has the efficacies of tranquilizing and allaying excitement, activating blood and promoting Qi. Pharmacodynamics research results show that the traditional Chinese medicine composition applied by lavage can remarkably shorten the sleep latency of mice induced by sodium pentobarbital of threshold dosage, prolong sleep time, strengthen the hypnotic effects of the sodium pentobarbital of the threshold dosage, induce the mice given with the sodium pentobarbital of the sub-threshold dosage, and strengthen the hypnotic effects of the sodium pentobarbital of the sub-threshold dosage.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and a preparation method thereof, in particular to a traditional Chinese medicine composition for treating insomnia and a preparation method thereof. Background technique [0002] Insomnia refers to the disturbance of the initiation and maintenance of sleep, which makes the quality and quantity of sleep unable to meet the individual's physiological needs, causing patients to feel that they have not fully rested and recovered their energy during the day, resulting in physical fatigue and listlessness. Drowsiness, decreased concentration, difficulty thinking, unresponsiveness, depressed mood, and restlessness. It is probably the most common clinical symptom after pain, and it is more common in women and the elderly. Insomnia is the most common sleep disorder with a high prevalence. In the United States, Australia and some European countries, the prevalence of insomnia is 35.2%. The in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61K9/20A61K9/48A61K9/16A61K9/14A61K9/10A61K47/32A61K47/34A61K47/38A61K47/40A61P25/20A61K47/10A61K47/36
Inventor 王建新张文鑫韩丽妹袁钧
Owner SHANGHAI JIANWU MEDICAMENT SCI & TECH
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