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Functional food for preventing and treating cardiovascular and cerebrovascular diseases and preparation method thereof

A technology for cardiovascular and cerebrovascular diseases and functional foods, which is applied in the field of functional foods for the prevention and treatment of cardiovascular and cerebrovascular diseases and its preparation. The effect of cardiovascular and cerebrovascular diseases

Inactive Publication Date: 2015-08-26
南京贝杉国际贸易有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Aiming at the problems of poor effect and large side effects of the existing treatment methods, the present invention provides a safe and effective functional food for the prevention and auxiliary treatment of cardiovascular and cerebrovascular diseases and its preparation method

Method used

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  • Functional food for preventing and treating cardiovascular and cerebrovascular diseases and preparation method thereof
  • Functional food for preventing and treating cardiovascular and cerebrovascular diseases and preparation method thereof
  • Functional food for preventing and treating cardiovascular and cerebrovascular diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Embodiment 1: Formula and preparation of functional food for preventing and treating cardiovascular and cerebrovascular diseases

[0026] A functional food formula for preventing and treating cardiovascular and cerebrovascular diseases, the formula components and proportions are: nattokinase 10%-20%, nitric oxide 10%-20%, coenzyme 10 5%-10%, red yeast rice extract 30%-50%, ginkgo biloba extract 20%-25%.

[0027] Coenzyme Q used in the present invention 10 Purchased from Xi'an Jinlv Biotechnology Co., Ltd., with a content of 98%; nattokinase was purchased from Beijing Nabain Food Co., Ltd.; nitric oxide was purchased from American Excellence Nutrition Company.

[0028] Preparation of the present invention comprises the following steps:

[0029] (1) Preparation of Red Yeast Extract:

[0030] Weigh a certain amount of red yeast rice powder → reflux extraction with 8 times the amount of 70%-80% ethanol for 3 times, each time for 2 hours → combine the extracts, remove the e...

Embodiment 2

[0037] Embodiment 2: toxicity test

[0038] According to "Food Safety Toxicological Evaluation Procedures and Methods" GB15193-2003, the food safety toxicology evaluation is carried out on the food of the present invention.

[0039] experiment method:

[0040] 1. Acute toxicity test: using the maximum tolerance test, select 20 Kunming mice with a body weight of 18-22g, half female, 25g functional food for preventing and treating cardiovascular and cerebrovascular diseases, add distilled water to 60mL (up to the maximum volume of mice for intragastric administration) Concentration), gavage twice a day, cumulative dose 25g / kg·bw, observe continuously for two weeks after gavage, record poisoning performance and death situation. The observation results showed no obvious symptoms of poisoning, and no death occurred during the 14-day observation period. After the observation period, the gross anatomy of the liver, kidney, lung, spleen and other organs of the mice was observed, and ...

Embodiment 3

[0057] Embodiment 3: Crowd observation experiment

[0058] (1), Experimental object:

[0059] The experimental group was divided into three age groups: 50-60 years old, 60-70 years old, and 70-80 years old. Each group selected 30 patients with cardiovascular and cerebrovascular diseases such as hypertension, hyperlipidemia, coronary heart disease, and atherosclerosis. The experimental group selected 30 people who also suffered from cardiovascular and cerebrovascular diseases, had similar conditions, and had similar living environment, level, and habits as the control group. Before the start of the experiment, blood pressure, blood lipid (total cholesterol, triglyceride, high-density lipoprotein, low-density lipoprotein), electrocardiogram and other signs were checked for the experimental group and the control group.

[0060] (2) How to take it:

[0061] The functional food prepared according to the above-mentioned functional food formula for preventing and treating cardiovas...

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Abstract

The invention belongs to the technical field of food production, and in particular relates to functional food for preventing and treating cardiovascular and cerebrovascular diseases and a preparation method thereof. The functional food for preventing and treating cardiovascular and cerebrovascular diseases comprises the following components by weight: 10%-20% of nattokinase, 10%-20% of nitric oxide, 5%-10% of coenzyme Q10, 30%-50% of a red yeast rice extractive and 20%-25% of a ginkgo biloba extractive. Functional components with good effects in resisting cardiovascular and cerebrovascular diseases are combined scientifically and rationally; the functional food on the basis of dissolving thrombus, garbage and toxins deposited in blood vessel can enhance the elasticity and permeability of blood vessels, so as to reach the goals of clearing blood lipids and reducing blood pressure; and the coenzyme Q10 added in the functional food can protect the heart function, and enhance the body's own ability to reduce cholesterol and blood lipid. Through LD50 acute toxicity test, 30 days feeding test, and crowd efficacy observation experiments, the functional food provided by the present invention is proved to be safe, nontoxic and effective.

Description

technical field [0001] The invention belongs to the technical field of food production, and in particular relates to a functional food for preventing and treating cardiovascular and cerebrovascular diseases and a preparation method thereof. technical background [0002] Cardiovascular and cerebrovascular diseases mainly include myocardial infarction, angina pectoris, hypertension, atherosclerosis, coronary heart disease, cerebral hemorrhage, cerebral thrombosis, etc. It is a common disease that seriously threatens the health of human beings, especially middle-aged and elderly people over 50 years old. It has the characteristics of "high morbidity, high mortality, high recurrence rate, and many complications". The number of people who die of cardiovascular and cerebrovascular diseases in the world is as high as 15 million every year, and it is the number one killer of human death. The "silent evil" of human health. [0003] The main cause of cardiovascular and cerebrovascula...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/16A23L1/28A61P9/00A61P9/10A61K31/122A61K38/48A61K33/02
Inventor 侯国新朱海伦傅庭治代然
Owner 南京贝杉国际贸易有限公司
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