Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Medicine composition capable of eliminating the mass and relieving swelling, absorbing clots and alleviating pain, preparation method and quality control method thereof

A quality control method, a technology for removing blood stasis and relieving pain, which is applied to drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas, etc.

Active Publication Date: 2009-04-29
ANGUO YADONG PHARMA
View PDF0 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Moreover, mastectomy, radiotherapy, and chemotherapy all have certain limitations. Therefore, it is very necessary to invent a practical and effective drug for the treatment of breast cancer.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Medicine composition capable of eliminating the mass and relieving swelling, absorbing clots and alleviating pain, preparation method and quality control method thereof
  • Medicine composition capable of eliminating the mass and relieving swelling, absorbing clots and alleviating pain, preparation method and quality control method thereof
  • Medicine composition capable of eliminating the mass and relieving swelling, absorbing clots and alleviating pain, preparation method and quality control method thereof

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0038] Experimental example 1 Process experimental research

[0039] 1. Crushing fineness test

[0040] Prepare the medicinal materials according to the prescription, each containing 10g musk, 90g cochinchinensis (without the shell and oil), 90g sesame root, 90g sweetgum, frankincense (preparation) 40g, myrrh (preparation) 40g, Wulingzhi (vinegar) Stir-fried) 90g, angelica (wine stir-fried) 40g, earthworm 90g, and fragrant ink 8g, respectively, are divided into four groups for experiments: the grinding fineness is: 50 mesh, 65 mesh, 80 mesh, 100 mesh, respectively, according to the pellet viscosity, The appearance of pellets and crushing loss are indicators to determine the fineness of crushing. The results are shown in Table 1:

[0041] Table 1: Crushing test results

[0042]

[0043] The above results show that when the crushing fineness is 80 meshes, the indicators are better, so 80 meshes are used in production.

[0044] 2. Starch adding water test

[0045] Configure accordi...

experiment example 2

[0052] Experimental example 2 Experimental research on identification method

[0053] 1. Angelica identification test screening

[0054] (1) Preparation of test solution

[0055] Method 1: Take 3.85g of the original medicinal material equivalent to the pharmaceutical preparation of the present invention, grind it, add 20ml of ethyl ether, sonicate for 10 minutes, filter, evaporate the filtrate, add 1ml of ethanol to the residue to dissolve it, and use it as the test solution.

[0056] Method 2: Take 3.85g of the original medicinal material of the present invention, grind it, add 20ml of ethyl ether, sonicate for 20 minutes, filter, evaporate the filtrate, add 1ml of ethanol to the residue to dissolve it, and use it as the test solution.

[0057] Method 3: Take 3.85g of the original medicinal material of the present invention, grind finely, add 20ml of ethyl ether, sonicate for 30 minutes, filter, evaporate the filtrate, add 1ml of ethanol to the residue to dissolve it, and use it ...

experiment example 3

[0108] Experimental example 3 Check item experimental research

[0109] Research on heavy metals and arsenic salts

[0110] 1 Heavy metal inspection

[0111] Determination method: Take 2g of the fine powder of this product, place it in a crucible, carbonize at low temperature, and then completely ash at 600°C, add 2ml of hydrochloric acid to the residue, evaporate in a water bath, add 15ml of water, and check according to law (Chinese Pharmacopoeia 2005 Edition One Appendix IX E The second method). A total of three batches of samples were checked for heavy metal limits according to the determination method, and the content was less than 10 ppm, so they were not included in the text. The results are shown in Table 1.

[0112] Table 1 Heavy metal inspection results of three batches of samples

[0113]

[0114] 2 Arsenic salt inspection

[0115] test methods:

[0116] Preparation of standard arsenic spots: According to the first method under item F of Appendix IX F of the 2005 edit...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a pharmaceutical composition used for eliminating stagnation, reducing swelling, resolving blood stasis and relieving pain, and a preparation method and a quality control method thereof. The raw materials of the pharmaceutical composition consist of musk, semen momordicae (going through shelling and oil removal), prepared kusnezoff monkshood root, resin of sweetgum, frankincense (prepared), myrrh (prepared), excrementum pteropi (going through stir-heating with rice vinegar), angelica (going through stir-heating with liquor), earthworm and prepared ink. The preparation method comprises the steps: in the ten ingredients, except the artificial musk, other nine ingredients such as semen momordicae and the like are ground into fine powder; the artificial musk is porphyrized and matched with the fine powder; and the powder is sieved and directly prepared into clinically acceptable dose form by regular procedures or adding pharmaceutically acceptable inborn nature agents. The quality control method comprises the steps of carrying out microscopical identification to the medicine composition, carrying out thin-layer identification to the angelica, the frankincense and the earthworm, carrying out limit tests to aconitine in the kusnezoff monkshood root and carrying out content measurement to muscone in the musk. The pharmaceutical composition has very good effects of eliminating stagnation, reducing swelling, resolving blood stasis and relieving pain.

Description

Invention field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition having the functions of dispelling masses, reducing swelling, removing blood stasis and relieving pain, and also relates to a preparation method and quality control method of the composition, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] Breast cancer is the most common malignant tumor in humans and one of the main malignant tumors in women. According to estimates by the American Cancer Society, there are 120,000 new cases of breast cancer in the United States each year, with an incidence rate of 72.2 per 100,000. The number of people who died of breast cancer in 1976 was 33,000. The incidence of breast cancer in different regions of our country is different, although our country has a low incidence of female breast cancer in the world. However, the incidence of breast cancer has...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/714A61K9/08A61K9/10A61K9/12A61K9/20A61K9/48A61P29/00G01N30/02G01N30/90A61K35/24A61K35/55A61K35/64A61K35/32A61K35/62
Inventor 付立家付建家
Owner ANGUO YADONG PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com