Traditional Chinese medicine composition with antibiotic and anti-inflammation action and preparation method and quality control method thereof
An antibacterial, anti-inflammatory and composition technology is applied in the fields of traditional Chinese medicine compositions and their preparation methods and quality control, and can solve the problems of long heating time of medicinal materials, large loss of effective components, complicated operation and the like
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Embodiment 1
[0089] Take 800g of Houttuynia cordata and cut into 2-3cm sections, mix with 200g of honeysuckle, add 8 times the amount of pH 2.0 acid water to soak for 1 hour, extract volatile oil by steam distillation for 2 hours, collect 800ml of the first distillate, and distill the first distillate Then carry out redistillation, collect 100ml of heavy distilled liquid, separate the volatile oil for later use; filter the medicinal liquid after extracting the volatile oil, put it aside, add 6 times the amount of water to decoct the dregs of the medicine for 0.5 hours, filter, combine the two filtrates, and concentrate at 60°C To a relative density of 1.06, add ethanol to make the alcohol content to 60%, let it stand for 12 hours, and filter; recover the ethanol from the filtrate until it has no alcohol smell, dry it under reduced pressure, and grind it into 100 mesh powder; The ratio is volatile oil: β-cyclodextrin = 1:6, the inclusion temperature is 40°C, and the inclusion time is 90 minu...
Embodiment 2
[0091] Cut 800g of Houttuynia cordata into 2-3cm sections, mix with 200g of honeysuckle, add 12 times the amount of pH 5.0 acid water, soak for 4 hours, extract volatile oil by steam distillation for 6 hours, collect 1200ml of initial distillate, and distill the first distillate Then carry out redistillation, collect 400ml of heavy distilled liquid, separate the volatile oil for later use; filter the medicinal liquid after extracting the volatile oil, put it aside, add 10 times the amount of water to decoct the medicinal residue for 2 hours, filter, combine the filtrate twice, and concentrate at 60°C To a relative density of 1.10, add ethanol to make the alcohol content to 90%, let it stand for 48 hours, and filter; recover the ethanol from the filtrate until it has no alcohol smell, dry it under reduced pressure, and crush it into 100 mesh powder; For volatile oil: β-cyclodextrin = 1:6, inclusion temperature 40°C, inclusion time 90min to make β-cyclodextrin inclusion compound,...
Embodiment 3
[0093] Cut 800g of Houttuynia cordata into 2-3cm sections, mix with 200g of honeysuckle, soak in 10 times the amount of pH4.0 acidic water for 3 hours, extract the volatile oil by steam distillation for 4 hours, collect 1000ml of the first distillate, and distill the first distillate Then carry out redistillation, collect 200ml of heavy distilled liquid, separate the volatile oil for later use; filter the medicinal liquid after extracting the volatile oil, put it aside, add 8 times the amount of water to decoct the dregs of the medicine for 1 hour, filter, combine the filtrates twice, and concentrate at 60°C To a relative density of 1.06-1.10, add ethanol to make the alcohol content to 75%, let it stand for 24 hours, and filter; recover the ethanol from the filtrate until it has no alcohol smell, dry it under reduced pressure, and grind it into 100 mesh powder; use saturated aqueous solution method for volatile oil, pack The mixing ratio is volatile oil: β-cyclodextrin = 1:6, t...
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