Pharmaceutical preparation containing arginine glutamic acid

Abstract

The invention relates to the medicament preparation of arginine glutamic acid and the preparation method and the application thereof. Through long-term experimental study, the personnel of the invention develops the medicament preparation of the arginine glutamic acid, the preparation takes the arginine glutamic acid as raw material medicine, which prepares the preparation with proper medicinal auxiliary material. The operating process of the medicament preparation of the invention is simple, the environmental pollution is small, and the invention is suitable for the production of a great industry. A pharmacological test shows that the medicament preparation of arginine glutamic acid has a very obvious pharmacological function on the aspect of the remedy of the hyperammonemia caused by acute liver disease and chronic liver disease such as hepatocirrhosis, fatty liver and hepatitis.

Description

technical field [0001] The invention belongs to the field of medicine and pharmacy, and in particular relates to a preparation method and application of an arginine glutamic acid pharmaceutical preparation. Background technique [0002] The liver is the largest organ in the human body and has the functions of synthesizing, storing, metabolizing, and detoxifying various nutrients. Severe damage to human liver function can lead to disorders of ammonia metabolism in the body, resulting in a state of high blood ammonia in the body, causing damage to important organs of the human body, such as liver damage and hepatic encephalopathy. Liver injury includes chemical liver injury, mechanical liver injury and hepatitis. The clinical treatment of hepatic encephalopathy caused by liver injury generally adopts a comprehensive treatment plan such as adjusting diet, adjusting amino acid profile, and maintaining acid-base electrolyte balance. At present, there are very few blood ammonia-...

AI Technical Summary

Problems solved by technology

However, due to the characteristics of the product itself, the three drugs generally need to be used in combination to achieve a better effect of reducing blood ammonia. There are many limitations in its clinical application, and blood gas analysis and potassium and sodium content must be measured during the medication.

Such cumbersome medication operations are very unfavorable for emergency treatment; and because a large amount of potassium ions, sodium ions and chloride ions are brought into the medication, it is very easy to cause electrolyte imbalance in the patient's body, and potassium ions have a significant stimulating effect on blood vessels. Patients are often in excruciating pain