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Chinese medicine composition for treating gynecopathy, the preparing method and the function

A composition and traditional Chinese medicine technology, which is applied to the traditional Chinese medicine composition of fungal, trichomonas and non-specific vaginitis to treat humid tropical conditions. The preparation field of the Chinese medicine composition can solve the problem that effervescent tablets cannot lower vaginal pH Viscous matrix is ​​excreted from the body for a long time and maintains a high drug concentration, etc., to achieve the effect of good appearance gloss, high capsule strength and membrane fracture, and outstanding antibacterial effect

Inactive Publication Date: 2007-10-31
杨文龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, traditional Chinese medicine is mostly used for local treatment in clinical treatment of gynecological diseases. The dosage forms of preparations include lotion, suppository and effervescent tablet, etc., but there are defects of low bioavailability and inconvenient use.
The lotion is easy to flow out and cannot maintain a high drug concentration in the vagina. The drug in the suppository is unevenly dispersed, and the viscous matrix needs to be excreted for a long time. However, the effervescent tablet cannot lower the vaginal pH, and the preparation process cost is high. If there is little vaginal secretion, it is difficult to disintegrate the drug

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] Prescription: Cnidium 3g, Honeysuckle 3.5g, Gardenia 6.24g, Tujingpi 6.26g, Phellodendron 10g, Scutellaria 3g, Sophora flavescens 5g, Kochia chinensis 6.24g, Yinchen 6.26g, Mint 15g, Artemisia argyi 12g, Duhuo 3g, Atractylodes 3.5g, Shichangpu 12.4g

[0065] Preparation:

[0066] Add water to decoct the above 14 herbs twice, each time for 1.5 hours, collect volatile oil at the same time, combine the decoction, filter, and concentrate the filtrate under reduced pressure to an extract with a relative density of 1.15 at 60°C, spray-dry to obtain a spray-dried powder Wherein the amount of water added is 8 times of the total weight of 14 raw materials, the air inlet temperature of spray drying is 180 ℃, and the air outlet temperature is 75 ℃.

[0067] The prepared spray-dried powder and volatile oil and medically acceptable amount of suspending agent beeswax and dispersant rapeseed oil are prepared into soft capsules; wherein the weight ratio of spray-dried powder, beeswax ...

Embodiment 2

[0069] Prescription: Cnidium 4.5g, Honeysuckle 6.24g, Gardenia 6g, Tujingpi 6.24g, Phellodendron 3g, Scutellaria 5g, Sophora flavescens 6.24g, Kochia 9g, Capillary 4g, Mint 12g, Artemisia argyi 8g, Duhuo 6.26 g, Cangzhu 3g, Shichangpu 10g

[0070] Preparation:

[0071] Add water to decoct the above 14 herbs for 3 times, the first time is 2 hours, the second time is 1.5 hours, the third time is 1 hour, and the volatile oil is collected at the same time, the decoction is combined, filtered, and the filtrate is concentrated under reduced pressure to the relative density at 60°C The medicinal extract of 1.10 was spray-dried to obtain a spray-dried powder; wherein the amount of water added was 6, 7, and 10 times of the total weight of the 14 raw materials, and the air inlet temperature of the spray drying was 170°C and the outlet air temperature was 95°C.

[0072] The prepared spray-dried powder and volatile oil and medically acceptable amount of suspending agent aluminum monostea...

Embodiment 3

[0074] Prescription: Cnidium 6.26g, Honeysuckle 3g, Gardenia 7.5g, Tujingpi 10g, Phellodendron 4g, Scutellaria chinensis 8g, Sophora flavescens 6.26g, Kochia chinensis 10g, Yinchen 7g, mint 12.4g, Artemisia argyi 3g, solitary life 8g , Cangzhu 10g, Shichangpu 15g

[0075] Preparation:

[0076] Add water to decoct the above 14 herbs twice, the first time for 1 hour, and the second time for 2 hours. At the same time, collect the volatile oil, combine the decoction, filter, and concentrate the filtrate under reduced pressure to an extract with a relative density of 1.30 at 60°C. Spray drying to obtain spray-dried powder; the amount of water added is 10 and 9 times the total weight of the 14 raw materials respectively, the air inlet temperature of spray drying is 190°C, and the outlet air temperature is 60°C.

[0077] The prepared spray-dried powder and volatile oil and medically acceptable amount of suspending agent lecithin and dispersant sesame oil are prepared into soft capsu...

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PUM

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Abstract

Disclosed is a Chinese pharmaceutical composition and its preparation, which consists of proportioning cnidium fruit, honeysuckle flower, cape jasmine, cortex pseudolaricis, corktree bark, baikal skullcap root, flavescent sophora root, broom cypress fruit, oriental wormwood, mentha, Chinese mugwort leafmulberry leaf, pubescent angelica root, atractylodes rhizome and grassleaved sweetflag rhizome, watering and boiling three times, gathering volatile oil, merging the grilling liquid, filtering, depression concentrating the filtrate to clear grease with specific gravity of 1. 10-1. 30 (measured at 60 deg. C), drying to obtain dried spray powder, finally charging medically acceptable amount of medicinal auxiliary materials into the volatile oil and the dried spray powder.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating gynecological diseases, in particular to a traditional Chinese medicine composition for treating damp tropical, fungal, trichomonas and non-specific vaginitis, and the invention also relates to a preparation method of the traditional Chinese medicine composition and its uses. Background technique [0002] Women's humid tropics, fungal, trichomonas and non-specific vaginitis are common gynecological diseases. At present, local traditional Chinese medicine is mostly used in clinical treatment of gynecological diseases, and the dosage forms of preparations include lotion, suppository and effervescent tablet, etc., but there are defects of low bioavailability and inconvenient use. The lotion is easy to flow out and cannot maintain a high drug concentration in the vagina. The drug in the suppository is unevenly dispersed, and the viscous matrix needs to be excreted for a long ...

Claims

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Application Information

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IPC IPC(8): A61K36/884A61K9/48A61K9/00A61P15/00A61P15/02A61P31/10A61P33/02
Inventor 杨文龙
Owner 杨文龙
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