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Ginseng, astragalus diabetes dropping pills

A technology for quenching thirst and dropping pills, which is applied in pill delivery, plant raw materials, metabolic diseases, etc. It can solve the problems of inconvenient taking, long dissolution time, and low dissolution rate for patients, and achieve accurate dosage, reliable curative effect, and controllable quality Effect

Inactive Publication Date: 2007-08-29
陈文展 +1
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0019] Other preparations based on this prescription include capsules, tablets, etc. Due to preparation technology and other reasons, most oral preparations of traditional Chinese medicines have long dissolution time, low dissolution rate, and poor absorption after taking them. , low bioavailability and hepatoenteric first-pass effect
These factors all affect the efficacy of various dosage forms of Shenqi Xiaoke, and directly affect the effect of treatment.
At the same time, the selection of condensing agent in the existing drop pill preparation technology is also difficult to meet the forming requirements of large-scale drop pills, so it is impossible to prepare large-scale drop pills of more than 100 mg
Many traditional Chinese medicine dripping pill preparations have a single dose of more than 20 pills, which brings great inconvenience to patients.
Especially for elderly patients, it is very inconvenient

Method used

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  • Ginseng, astragalus diabetes dropping pills

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0045] Example 1 Choose different substrates, different ratios of drug extract dry powder and substrates, and choose different dropper temperatures to carry out prescription tests.

[0046] Experimental design: in order to observe under the following conditions: 1. select different substrates, 2. select different proportions for the same substrate, 3. select different lowering temperatures for the same substrate and the same proportion to carry out the influence of the prescription on the products involved in the present invention, respectively use Polyethylene glycol-4000, polyethylene glycol 6000, polyethylene glycol 4000+polyethylene glycol 6000 and other bases are mixed with raw material powder, respectively according to the dry powder of drug extract: matrix = 1:1 / 1:1.5 / 1 : 2 proportioning, other all according to the given condition in [specific implementation mode], adopt the mode of electric heating that each group of prepared raw and auxiliary materials are heated to mo...

example 2

[0047] Select the test of different condensing agents in the preparation process of example two

[0048] Experimental design: In order to observe the influence of different condensing agents selected in the preparation process on the products involved in the present invention, liquid paraffin, soybean oil, and methyl silicone oil were used as condensing agents respectively, and the others were all in accordance with the conditions given in [specific implementation methods], The matrix is ​​mixed with polyethylene glycol 4000 and dry powder at a ratio of 1.5:1, and the prepared raw and auxiliary materials of each group are heated to a molten state by electric heating, and a special dropping pill machine is used to adjust the dripper temperature respectively. Keep it at 70±2°C; adjust the refrigeration control system of the dripping pill machine to keep the temperature of the condensing agent at 20→-5°C, and then prepare respectively according to the process given in the previous...

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Abstract

The present invention discloses an oral Chinese medicine preparation-Shenqi Xiaoke dripping pills with the functions of supplementing qi and nourishing yin for effectively curing diabetes with obvious therapeutic effect. It is made up by using 13 Chinese medicinal materials of ginseng, astragalus root and others through a certain preparation process.

Description

technical field [0001] The invention relates to a Shenqi Xiaoke drop pill preparation for nourishing qi and nourishing yin, which is mainly prepared from 13 raw materials such as ginseng and astragalus, and is used for thirst, polydipsia, polyuria, and lack of energy in diabetes , dizziness (type II diabetes). This preparation uses ginseng, astragalus, yam, Atractylodes macrocephala, schisandra, Ophiopogon japonicus, Radix Polygonatum, Rehmannia glutinosa, Achyranthes bidentata, Poria cocos, Alisma, burdock seed, silkworm 13 traditional Chinese medicines as raw materials, and is modified from Shenqi Xiaoke granule A kind of oral drop pill preparation formed. Background technique [0002] Diabetes is mainly due to insufficient insulin secretion in the body (absolute deficiency) or increased demand for insulin (relative deficiency), and then blood sugar rises and urine sugar appears, resulting in symptoms such as polyuria, polydipsia, polyphagia, physical strength, and weight...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61K9/20A61P3/10
Inventor 陈文展王伟
Owner 陈文展
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