Synthetic method for epoxy sclareol
A synthesis method and technology of sclareol, applied in the direction of organic chemistry and the like, can solve the problems of high cost, poor safety, explosion and the like, and achieve the effect of low product cost
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0026] 30.8g of sclareol was dissolved in 90mL of 1,2-dichloroethane, and 1.5g of 12-phosphotungstic acid, 0.72g of cetylpyridine chloride and 35mL of 30% aqueous hydrogen peroxide were added to adjust pH≈2.0 , the reaction was vigorously stirred at 70 °C for 12 hours. The obtained reaction mixture was separated and purified by conventional methods to obtain 30.4 g of epoxysclareol as a white solid with a yield of 93.8%. Melting point 131 ~ 132 ℃.
Embodiment 2
[0028] 30.8g of sclareol was dissolved in 60mL of chloroform, and 0.41g of sodium tungstate dihydrate, 0.72g of sodium dihydrogen phosphate, 0.36g of cetylpyridinium chloride and 90mL of 10% hydrogen peroxide solution were added to adjust pH≈1.5 , the reaction was vigorously stirred at 70 °C for 24 hours. The obtained reaction mixture was separated and purified by conventional methods to obtain 28.4 g of epoxysclareol as a white solid with a yield of 87.8%. Melting point 130 ~ 132 ℃.
Embodiment 3
[0030] 30.8 g of sclareol was dissolved in 60 mL of ethyl acetate, 2.0 g of hexadecylphosphotungstic acid pyridinium salt and 21 mL of 50% aqueous hydrogen peroxide solution were added, and the reaction was vigorously stirred at 70° C. for 8 hours. The obtained reaction mixture was separated and purified by conventional methods to obtain 30.2 g of epoxysclareol as a white solid with a yield of 93.2%. Melting point 130 ~ 132 ℃.
PUM
Property | Measurement | Unit |
---|---|---|
melting point | aaaaa | aaaaa |
melting point | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com