The invention discloses a CPRI-based data transmission method, apparatus and device, and a storage medium. The method comprises the steps of receiving user plane data, control plane data, management plane data and synchronous clock data; mapping the user plane data, the control plane data, the management plane data and the synchronous clock data into a CPRI frame; and sending the CPRI frame to an O-RAN radio frequency unit through a first serial deserializer, so that the O-RAN radio frequency unit receives the CPRI frame through a second serial deserializer, analyzes the CPRI frame, analyzes user plane data, control plane data, management plane data and synchronization plane data from the CPRI frame, and sends the user plane data, the control plane data, the management plane data and the synchronization plane data to the O-RAN radio frequency unit. And sending the user plane data, the control plane data, the management plane data and the synchronization plane data to a second physical layer for processing. According to the invention, the technical problem that the data transmission process of the existing 5G technology forward transmission interface is complex is solved.