The present invention relates to a wheel deburring device, which comprises a machine frame, motors, guide rails, a lead screw, sliding tables, cylinders, a brush, etc. Conveying roller ways enable a wheel to reach approximate middle positions of four V-type rollers, the wheel is lifted by lifting cylinders, a pneumatic motor drives the lead screw to rotate so as to enable a left sliding table and a right sliding table to drive the four V-type rollers to synchronously clamp the wheel, and a drive motor is used for achieving the rotation of the wheel in a clamped state. A servo motor drives the brush to rotate, rising and falling cylinders lift the brush through four guide posts, certain pressure is applied to the brush when the brush is in contact with flange corners of the wheel, then, the brush starts to remove burrs from the flange corners of the wheel, a servo electric cylinder I is used for achieving angle adjustment on the brush, and a servo electric cylinder II is used for achieving position adjustment on the brush through guide rails I; and when the brush is adjusted to an appropriate angle, the burr removal of rim corners can be completed, and thus the wheel deburring device can adapt to wheels of any model.