Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Compounds for altering food intake in humans

a technology of modifying food intake and compounds, which is applied in the direction of biocide, plant/algae/fungi/lichens, drug compositions, etc., can solve the problems of inability to meet the needs of people, so as to improve the effect of human health, control the intake of food, and modify the eating habits

Inactive Publication Date: 2005-11-10
AVOCA
View PDF18 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

"The present invention provides a process for extracting components from a jojoba plant that contain simmondsin compounds. These components can be used as a dietary supplement or to modify eating habits and control weight. The process involves heating and mixing the jojoba plant with an organic solvent to create a solvent containing the extracted components. The solvent is then separated from the insoluble parts of the plant. The resulting mixture is concentrated and dried to create a powder that can be formulated into various forms for ingestion or administration. The jojoba extracts can be used to control weight, decrease desire for food, and promote good eating habits. They can also be used as a dietary supplement to replace or supplement food intake. The process provides a natural and effective way to manage weight and improve physical performance."

Problems solved by technology

For example, phenteramine has potential side-effects like nervousness, insomnia, and constipation.
Moreover, patients generally develop a tolerance to the drug, and certain programs lasting longer than about eight weeks often are not desirable or feasible.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0043] Jojoba meal (purchased as de-fatted jojoba meal from American Mercantile Corporation) is extracted using ethanol and water at a ratio of 80 percent ethanol and 20 percent water, on a weight to weight basis. In particular, about 6 liters of the ethanol / water mix and about 1 kilogram of the jojoba meal are added to a slurry extractor. The resulting mixture is heated to 60° C., and held at that temperature for one hour while mixing is continued. The resulting mixture is filtered through a centrifuge, and the centrifuge cake is washed with an ethanol / water mix until the dissolved solids leaving the centrifuge is less than 1 weight percent. The resulting liquid comprising water, ethanol and the dissolved solids of the jojoba meal is concentrated by heating to 50° C. under reduced pressure (relative to atmospheric pressure) of 27 inches of water column vacuum, using a distillation unit. As a result, there is obtained a water, ethanol and extract mixture (supernatant) having a conce...

example 2

[0044] Jojoba extract is provided as described in Example 1. The resulting powder, which contains about 12 weight percent of simmondsin compounds (as determined by high performance liquid chromatography), is formed into capsules of approximately 250 mg in weight. The capsules were ingested by 16 human subjects. Those subjects ingested between 2 and 5, usually 3 or 4, of those capsules throughout (normally from 1 to 3 times) a 24 hour day. Of those subjects, 11 reported weight loss. Those subjects reporting positive results reported weight loss, appetite suppression and an increase in energy. Some subjects reported having diarrhea.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
boiling pointaaaaaaaaaa
temperatureaaaaaaaaaa
temperatureaaaaaaaaaa
Login to View More

Abstract

The present invention relates to a process of providing an extract containing at least one simmondsin compound. The extract is provided from jojoba plant, and used as a dietary supplement for use in a weight control regiment in humans. The present invention also provides a method of treating an overweight human in need of such treatment, and comprises administering a therapeutically effective amount of such an extract.

Description

FIELD OF THE INVENTION [0001] The present relates to materials derived from jojoba plants that are useful for promoting good health and feeling of well-being, and particularly for altering food intake in humans, and more particularly to materials useful for suppressing appetite, and in human weight control programs. BACKGROUND OF THE INVENTION [0002] With respect to humans and appetite suppression or weight control, a wide variety of low-calorie foods, dietary supplements, pharmaceuticals, medical foods, functional foods and nutraceutical agents have been suggested. Additionally, a number of dietary weight loss and weight control programs have been suggested, many of which incorporate the use of dietary supplements or therapeutic agents. Known therapeutic agents (e.g., as drugs) and known dietary supplements act by a variety of mechanisms. Exemplary drugs include epinephrine (as a pure substance, or in the form within the ephedra herb), norepinephrine, 5-hydroxytryptamine (e.g., fle...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(United States)
IPC IPC(8): A61K36/185C07H15/00
CPCY10S514/909A61K36/185
Inventor TEAGUE, RICHARD KINGTYNCH, SAMUEL LEONARDJAKSCH, FRANK LOUIS JR.MAIER, RICHARD THEODORE JR.
Owner AVOCA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products