Colloid pectin bismuth dry suspensoid and its preparing process

Abstract

The invention discloses a dried suspension of colloid pectin bismuth which comprises the following constituents (by weight ratio): colloid pectin bismuth (calculated by bismuth) 50-300 parts, filling agent 600-2500 parts, flavoring agent 50-300 parts, flocculating agent 5-60 parts. The colloid has hemostatic action for hemorrhage of digestive tract.

Description

technical field [0001] The invention relates to a bismuth agent, in particular to a colloidal bismuth pectin bismuth agent. Background technique [0002] Colloidal pectin bismuth bismuth is a gastric mucosal protective agent, which forms a stable gel in the gastric acid environment, covers the mucosal surface, isolates the erosive surface and ulcer focus from gastric acid and pepsin, and protects the damaged mucosa Promote the repair and healing of ulcer tissue; stimulate the production of endogenous prostaglandins and epidermal growth factors, accelerate the healing of ulcers and the disappearance of inflammation, and have a certain hemostatic effect. [0003] Dun Wen and Zhou Erfeng studied the effect of colloidal bismuth pectin on experimental gastric and duodenal ulcers in rats. On the rat model of gastroduodenal ulcer, the effect of bismuth pectin against experimental duodenal ulcer was observed, and compared with Dele, the results: (1) The effect of bismuth pectin on ...

AI Technical Summary

Problems solved by technology

[0005] Although antacids are cheap, their curative effect is poor and their side effects are large, so they are rarely used clinically at present; although H2 receptor antagonist proton pump inhibitors have a good inhibitory effect on the secretion of gastric acid and have mild side effects, due to their Mucosa protective effect and weak effect on Helicobacter pylori, so the recurrence rate of ulcer is high; usually it needs to be combined with mucosal protective agent and used in combination for the treatment of peptic ulcer