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Astragalus mongholicus tablet, and its preparation and active constituent content measuring method

A technology of astragalus and content, which is applied in the preparation and content determination, and various tablet dosage forms of astragalus, and can solve the problems that have not yet been reported on the application of single prescription tablets.

Inactive Publication Date: 2006-08-09
SICHUAN GUOKANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its unilateral preparations have oral liquids, granules, capsules (new drug protection) and injections on the market, but there are no reports on its unilateral tablets and their applications.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0006] Take 3750g of Radix Astragali, add water and decoct 1 to 6 times, add 10 to 15 times the amount of water for the first 2 to 3 hours, add 8 to 16 times the amount of water for the second 1 to 2 hours, combine the decoction, and filter , the filtrate is concentrated to a relative density of about 1.26-1.30 (50°C), adding ethanol to make the ethanol content 70%, stir well, let stand, take the supernatant to recover ethanol, and concentrate to a relative density of 1.20-1.50 (38°C ), add appropriate amount of auxiliary materials, mix well, granulate, dry at low temperature, press into 1000 tablets, coat with film, and get final product.

Embodiment 2

[0008] Take 7500g of Radix Astragali, make a clear ointment as above, take another 200g of polyethylene glycol and mix it with 1 / 5 amount of polyethylene glycol 400, then pulverize it with a colloid mill, then add the remaining amount of polyethylene glycol 400 for miscibility, and take another microcrystalline fiber 45g, and 80g of dry starch crossed 120 mesh sieves, mix homogeneously, granulate, tabletting, obtain 2000 tablets of Radix Astragali Sustained Release Tablets.

Embodiment 3

[0010] Take 1500g of Astragalus membranaceus, and prepare a clear ointment according to the above method, and take 200g of lactose, 300g of polyvinylpyrrolidone, 800g of hydroxypropyl methylcellulose, and 300g of talcum powder for later use. Mix hydroxypropyl methylcellulose with astragalus extract clear paste, add lactose, make micro-pellets with polyvinylpyrrolidone, and press into tablets to obtain 3000 long-acting sustained-release tablets.

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PUM

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Abstract

The present invention provides a medicine for curing the diseases of cardio palmus, short breath, collapse, spontaneous perspiration, edema, chronic nephritis, proctoptosis and carbuncles. Said medicine is made up by using astragalus root extract as main component, can be made into various tablet form including general tablet (containing sugar-coated tablet), disintegrant tablet, chewing tablet, enteric soluble tablet and dispersing tablet, etc.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to various tablet dosage forms, preparation and content determination methods of Astragalus membranaceus. Background technique [0002] Astragalus membranaceus is a commonly used traditional Chinese medicinal material in clinical practice. Its various preparations and various compound preparations have wide clinical indications. It can be used for shortness of breath, palpitations, collapse, spontaneous sweating, edema, chronic nephritis, chronic diarrhea, prolapse of the anus, ulcers and sores. . Its unilateral preparations have dosage forms such as oral liquid, granules, capsules (new drug protection) and injections on the market, but there are no reports on its unilateral tablet and its application. Invention content: [0003] The medicine of the present invention is characterized by tablets. After a large number of prescription combinations, compatibility...

Claims

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Application Information

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IPC IPC(8): A61K36/481A61K9/20A61P1/14A61P13/12A61P1/12A61P17/02A61P7/10
Inventor 邓聪石万棋左治国陈家伟支春吴世龙万玲徐琨
Owner SICHUAN GUOKANG PHARMA
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