Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation method of arctium fruit extract for decreasing blood sugar

The technology of burdock seed and extract is applied in the field of preparation of burdock seed extract, which can solve the problems such as the preparation method of burdock seed extract that has not been found, and achieve the effects of hypoglycemic effect, less toxic and side effects, and significant effect.

Inactive Publication Date: 2005-01-26
SHANGHAI JIAO TONG UNIV
View PDF0 Cites 24 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After searching the prior art literature, no literature report on the preparation method of the burdock fruit extract with hypoglycemic effect has been found

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of arctium fruit extract for decreasing blood sugar
  • Preparation method of arctium fruit extract for decreasing blood sugar
  • Preparation method of arctium fruit extract for decreasing blood sugar

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Take burdock fruit, crush it into coarse powder, add 6 times the amount of petroleum ether to soak overnight, extract under reflux for 3 hours to degrease, and filter. Add 5 times the amount of 30% ethanol to the filter residue, extract twice at 90°C, each time for 1h, filter, combine the filtrates, concentrate to a relative density of 1.00 (measured at 60°C), and spray dry (inlet air temperature is 185°C, outlet air temperature is 80°C) ℃, the atomization pressure is 0.4Mpa, the extract flow rate is 2.5L / h), and the burdock fruit extract dry powder with a water content of less than 5% is obtained.

[0022] The implementation effect is to obtain a powdery solid with a slightly bitter taste, brown color, and a yield of 10%, and there is no clogging of the nozzle and the phenomenon of powder sticking into blocks during spray drying. The extract contains arctiin, arctigenin, and pogrosin , LappaolA, Lappaol C, Lappaol F, Lappaol H, Arctignan E, β-sitosterol and carotene 10...

Embodiment 2

[0024] Take burdock fruit, crush it into coarse powder, add 6 times the amount of n-hexane to soak overnight, reflux extraction for 4 hours to degrease, and filter. Add 8 times the amount of 65% ethanol to the filter residue, extract 3 times at 90°C, each time for 2h, filter, combine the filtrates, concentrate to a relative density of 1.15 (measured at 60°C), and spray dry (inlet air temperature is 235°C, outlet air temperature is 90°C) ℃, the atomization pressure is 0.3Mpa, and the flow rate of the extract is 1.8L / h), and the dry powder of the burdock fruit extract with a water content of less than 5% is obtained.

[0025] The effect of the implementation is to obtain a powdery solid with a slightly bitter taste, brown color and a yield of 25%, and there is no clogging of the nozzle and the phenomenon of powder sticking into blocks during spray drying. The extract contains arctiin, arctigenin, and pogrosin , LappaolA, Lappaol C, Lappaol F, Lappaol H, Arctignan E, β-sitosterol...

Embodiment 3

[0027] Take burdock fruit, crush it into a coarse powder, add 7 times the amount of cyclohexane to soak overnight, extract under reflux for 6 hours to degrease, and filter. Add 10 times the amount of 95% ethanol to the filter residue, extract twice at 75°C for 3 hours each time, filter, combine the filtrates, concentrate to a relative density of 1.10 (measured at 60°C), and spray dry (inlet air temperature is 210°C, outlet air temperature is 100°C) ℃, the atomization pressure is 0.2Mpa, the extract flow rate is 1.0L / h), and the burdock fruit extract dry powder with a water content of less than 5% is obtained.

[0028] The implementation effect is to obtain a powdery solid with a slightly bitter taste, brown color, and a yield of 18%, and there is no blocking of the nozzle and the phenomenon of powder agglomeration during spray drying. The extract contains arctiin, arctigenin, and pogrosin , LappaolA, Lappaol C, Lappaol F, Lappaol H, Arctignan E, β-sitosterol and carotene 10 co...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a preparation method of arctium fruit extract for decreasing blood sugar, wherein the extract comprises Arctiin, Matairesinol, Lappaol A, Lappaol C, Lappaol Fú¼LappaolHú¼Arctignan Eú¼beta-sitosterol and daucosterol.

Description

technical field [0001] The invention relates to a preparation method of the extract, in particular to a preparation method of the burdock fruit extract with hypoglycemic effect. It is used in the technical field of traditional Chinese medicine preparation. Background technique [0002] Burdock Fructus is a traditional Chinese medicine recorded in the 2000 edition of the "Chinese Pharmacopoeia". For measles, rubella, sore throat, mumps erysipelas, carbuncle sores, the dosage is 6-12g. [0003] With the improvement of living standards and the aging of the population, diabetes has become a frequently-occurring and common disease, and the incidence rate is increasing year by year. The incidence of diabetes is increasing rapidly in both developed and developing countries. Diabetes has become the third disease that seriously threatens human health after tumors and cardiovascular diseases, and is listed by WHO as one of the world's three major chronic diseases. At present, ther...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/7048A61P3/10
Inventor 徐朝晖贾伟邱明丰赵爱华
Owner SHANGHAI JIAO TONG UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com