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Adhesive plaster for curing neurodermatitis

A plaster and neurological technology, applied in the field of external preparations for the treatment of neurodermatitis, can solve the problems of telangiectasia, long-term medication, and aggravation of the disease, and achieve the effects of inhibiting proliferation, high cure rate, and reduced recurrence rate

Inactive Publication Date: 2004-10-13
王刚生
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although these drugs have a certain therapeutic effect, they need to be used for a long time and are prone to relapse after drug withdrawal, and sometimes the disease can be aggravated
In addition, corticosteroids themselves have certain side effects. Long-term use of corticosteroids for external use can lead to atrophy of the epidermis and dermis, thinning of the skin, and adverse reactions such as skin wrinkles, telangiectasia, and purpura.

Method used

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  • Adhesive plaster for curing neurodermatitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] The backing layer of the plaster is made of bleached fine cloth, the covering layer of the plaster is made of cellophane, and the plaster includes a matrix, a therapeutic drug and auxiliary materials.

[0036] Matrix preparation

[0037] The base is the base used in common rubber plasters, that is, weigh 16 parts each of raw rubber and rosin, 4 parts of lanolin, 1.5 parts of vaseline, 1 part of liquid paraffin, 20 parts of zinc oxide, and 45 parts of gasoline according to the following weight ratio.

[0038] Cut the raw rubber into strips, press it into a mesh film with a rolling machine, spread it on the wire mesh, remove the static electricity and let it cool, then immerse it in gasoline, seal it and soak it, so that the rubber is fully swollen, move it into the batching pot and stir, and add it one after another After melting and filtering lanolin, vaseline, and liquid paraffin, add zinc oxide, rosin, and stir to form a uniform matrix.

[0039] Take 1 kg of dacronin...

Embodiment 2-7

[0043]

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PUM

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Abstract

The present inventino provides an adhesive plaster preparation for curing neurodermatitis. It includes mounting layer, plaster surface covering layer and plaster material, and is characterized by that the composition of said plaster material includes (wt%) 0.5-5% of dyclonine, 0.25-5% of diphenhydranine and 90-99.25% of matrix. Its cure rate is high, and it has no any side effects.

Description

technical field [0001] The present invention relates to preparations for medical use, in particular topical preparations for the treatment of neurodermatitis. Background technique [0002] Neurodermatitis is a refractory and easily recurring skin nerve dysfunction skin disease. The clinical manifestations are characterized by lichenification and severe itching, accompanied by neurological abnormalities such as neurasthenia, insomnia, dreaminess, forgetfulness, and mood swings. Clinically, the rash and mental symptoms are mutually causal, often leading to a vicious circle, which brings great pain to the patient both mentally and physically. At present, when clinically treating neurodermatitis, the most commonly used drugs are external preparations containing corticosteroid hormones, such as triamcinolone ointment and Fujining (containing triamcinolone acetate-A) plaster. Though these medicines have certain curative effect, need medication for a long time and easily relapse ...

Claims

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Application Information

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IPC IPC(8): A61K9/06A61K31/4453A61P17/00
Inventor 王刚生
Owner 王刚生
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