External antipruritic composition for hemodialysis patients and preparation method of external antipruritic composition

A composition and patient technology, applied in the directions of drug combinations, boron compound active ingredients, hydroxyl compound active ingredients, etc., can solve the problems of threatening the life of patients, affecting the quality of life of patients, increasing medical expenses, etc., and achieve obvious synergy and onset of effect. Fast and less side effects

Pending Publication Date: 2022-07-15
赵岩
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As the dialysis time prolongs, the symptoms will gradually worsen, making the patient anxious and suffering all day long, which will seriously affect the quality of life of the patient. If the care is not done properly, the skin infection will increase the medical expenses and even threaten the life of the patient.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] An external antipruritic composition for hemodialysis patients, comprising an ointment prescription and an oil phase, the ointment prescription includes an antipruritic active component, and the antipruritic active component includes the following components by weight: 30 parts of artificial musk, 30 parts of artificial bezoar, 6 parts of pearl, 13 parts of calamine powder, 4 parts of borax, 17 parts of borneol, 78 parts of yellow petrolatum, 5 parts of lanolin and 4 parts of dimethyl sulfoxide, the oil phase includes skin repairing active components , the skin repair active components include the following components by weight, 16 parts of menthol, 10 parts of menthol oil, 16 parts of camphor, 10 parts of eucalyptus oil, 9 parts of clove oil, 13 parts of cinnamon oil, 6 parts of camphor oil , 21 parts paraffin, 9 parts beeswax and 20 parts Vaseline.

[0041] Crush the above artificial musk, artificial bezoar, pearl, calamine powder, borax and borneol into fine powder, ...

Embodiment 2

[0044] An external antipruritic composition for hemodialysis patients, comprising an ointment prescription and an oil phase, the ointment prescription includes an antipruritic active component, and the antipruritic active component includes the following components by weight: 25 parts of artificial musk, 25 parts of artificial bezoar, 5 parts of pearl, 10 parts of calamine powder, 3 parts of borax, 15 parts of borneol, 75 parts of yellow petrolatum, 4 parts of lanolin and 3 parts of dimethyl sulfoxide, the oil phase includes skin repairing active components , the skin repair active components include the following components by weight, 15 parts of menthol, 5 parts of menthol oil, 15 parts of camphor, 5 parts of eucalyptus oil, 8 parts of clove oil, 10 parts of cinnamon oil, 5 parts of camphor oil , 20 parts paraffin, 8 parts beeswax and 19 parts vaseline.

[0045] Crush the above artificial musk, artificial bezoar, pearl, calamine powder, borax and borneol into fine powder, th...

Embodiment 3

[0048] An external antipruritic composition for hemodialysis patients, comprising an ointment prescription and an oil phase, the ointment prescription includes an antipruritic active component, and the antipruritic active component includes the following components by weight: 35 parts of artificial musk, 35 parts of artificial bezoar, 7 parts of pearl, 15 parts of calamine powder, 5 parts of borax, 20 parts of borneol, 80 parts of yellow petrolatum, 6 parts of lanolin and 5 parts of dimethyl sulfoxide, the oil phase includes skin repairing active components , the skin repair active components include the following components by weight, 20 parts of menthol, 15 parts of menthol oil, 20 parts of camphor, 15 parts of eucalyptus oil, 10 parts of clove oil, 15 parts of cinnamon oil, 7 parts of camphor oil , 22 parts paraffin, 10 parts beeswax and 21 parts vaseline.

[0049] Crush the above artificial musk, artificial bezoar, pearl, calamine powder, borax and borneol into fine powder...

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PUM

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Abstract

The invention relates to the technical field of traditional Chinese medicine, in particular to an external antipruritic composition for a hemodialysis patient and a preparation method of the external antipruritic composition for the hemodialysis patient. The itching-relieving active component comprises the following components in parts by weight: 25-35 parts of artificial musk, 25-35 parts of calculus bovis factitius, 5-7 parts of pearl, 10-15 parts of calamine powder, 3-5 parts of borax and 15-20 parts of borneol, the oil phase comprises a skin repairing active component, and the skin repairing active component comprises the following components in parts by weight: 1-5 parts of an antioxidant and 1-5 parts of a lubricant. The ointment is prepared from the following raw materials in parts by weight: 15-20 parts of menthol, 5-15 parts of dementholized peppermint oil, 15-20 parts of camphor, 5-15 parts of eucalyptus oil, 8-10 parts of clove oil, 10-15 parts of cinnamon oil and 5-7 parts of camphor oil. According to the technical scheme, the traditional Chinese medicine composition has the effects of relieving itching, moistening dryness, preserving moisture and repairing skin, and has the advantages of being quick in effect taking, small in side effect, free of hormone, convenient to use, few in taboos, simple to prepare, capable of effectively reducing repeated attack of pruritus and the like.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to an external antipruritic composition for hemodialysis patients and a preparation method thereof. Background technique [0002] Itchy skin is one of the common complications of uremia. Studies have shown that 42%-52% of adult uremia patients have itchy symptoms. Secondary hyperparathyroidism is a major cause of skin pruritus. Chronic renal function In patients with failure, secondary hyperparathyroidism is caused by the decrease of phosphorus excretion, the repeated increase of blood phosphorus level and the decrease of blood ionized calcium level, which stimulates the secretion of parathyroid hormone (PTH). Studies have shown that secondary hyperparathyroidism can cause skin itching, and its increase can cause hypercalcemia, skin calcification and stimulate the release of histamine from skin mast cells. Therefore, the increase of PTH is considered to be an ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/61A61K9/00A61K47/44A61P17/04A61K31/045A61K31/125A61K33/22A61K33/30A61K35/413A61K35/55A61K35/618
CPCA61K35/55A61K35/413A61K35/618A61K33/30A61K33/22A61K31/045A61K36/534A61K31/125A61K36/61A61K36/54A61K9/0014A61K47/44A61P17/04A61K2300/00
Inventor 赵岩刘强李明景耿进瑜王林啸
Owner 赵岩
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