Microelectrode for continuous electrochemical detection of bioactive substances, biosensor and preparation method

Abstract

The invention provides a microelectrode for continuous electrochemical detection of bioactive substances, a biosensor and a preparation method, and relates to the field of electrochemical sensors. One end of the microelectrode for continuous electrochemical detection of bioactive substances is a connecting end, the other end of the microelectrode is an insertion end, and the microelectrode comprises an outer tube and an inner core which are respectively used as two electrodes connected with an external circuit. The outer tube comprises a porous tube body made of a metal material, noble metal films or carbon films deposited on the inner and outer surfaces of the porous tube body, carbon nanotubes fixed inside and outside the porous structure, and an enzyme reaction reagent; the inner core comprises a core body made of a magnetic material, and a silver and silver chloride film plated on the surface of the core body; the same end of the outer pipe is sleeved outside the inner core, and polymer electrolyte is filled between the outer pipe and the inner core. The positive electrode and the negative electrode are combined into a whole, the number of wounds on the human body is reduced, and stability and sensitivity of monitoring signals are guaranteed.

Description

technical field [0001] The application relates to the field of electrochemical sensors, in particular, to a microelectrode for continuous electrochemical detection of biologically active substances, a biosensor and a preparation method. Background technique [0002] With the development of society, the advancement of science and technology, and the improvement of people's living standards, health issues have become the focus of many people's daily attention, and more and more quick detection products have been produced to facilitate people to quickly and easily monitor their own health status. learn. Among them, biosensors are used for continuous detection of biologically active substances in the body, and play an important role in health monitoring, disease diagnosis and treatment. The monitoring of blood sugar is very important for diabetic patients, and the blood sugar value helps to evaluate the glucose metabolism disorder of diabetic patients. Real-time continuous dyn...

AI Technical Summary

Problems solved by technology

[0005] Existing portable dynamic blood glucose sensors generally contain 2 to 3 electrodes. During use, the front ends of all the electrodes need to be implanted under the human skin and stay on the superficial layer of the human skin, so at least 2 to 3 wounds are generated, which not only increases the The complexity of the operation is increased, and more wounds will cause certain psychological pressure on the patient

Moreover, the positive and negative electrodes are independent of each other. Due to the spatial separation of the two, in the liquid environment in the body, it will cause obstacles and interference to the ion transmission of the electrochemical test, affecting the stability and sensitivity of the signal.

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