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Composition helpful for skin whitening and wrinkle removal

A skin whitening and composition technology, which is applied in the field of compositions that help skin whitening and wrinkle removal, can solve the problems of lack of an integrated oral beauty maturation scheme, etc., so as to inhibit the formation of fine lines, promote collagen synthesis, and inhibit cheese The effect of aminidase activity

Pending Publication Date: 2021-10-22
上海楷达生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Looking at the current development of the oral beauty industry, collagen accounts for most of the market, but it is still in the category of "replenishing the shape with shape", which can only partially improve wrinkles, and lacks a mature solution for integrated oral beauty

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Mix 13.4kg of Shi Kesi brand melon concentrate powder (including 10kg of grape seed extract, 1.7kg of melon concentrate powder, and 1.7kg of vitamin C), 10kg of zinc-rich yeast powder, 1kg of acerola cherry powder, 1kg of sea buckthorn fruit powder, and concentrated aronia berries Fruit juice powder 1kg, licorice 1kg, lycopene 1kg, sorbitol 15kg, microcrystalline cellulose 16.3kg, magnesium stearate 0.3kg are mixed and stirred evenly, directly carry out tabletting, each tablet weight is 400mg, obtains semi-finished product. Put the semi-finished product into a PET bottle and keep it sealed to get the final product.

Embodiment 2

[0019] Embodiment 2 human fibroblast culture experiment in vitro

[0020] All test solutions were prepared in the presence of S9 (an enzyme-containing liver extract). S9 was prepared from rat liver after homogenization and low-temperature centrifugation, and the supernatant was prepared. ml, the solution has multiple activated substrates, which can simulate liver metabolism. The oral tablet prepared in Example 1 was prepared into a 550 μg / mL solution with S9 solution as the efficacy group for future use. Another 100 μM vitamin C solution was prepared as the VC group (with the same VC content as in the efficacy group) for later use.

[0021] Human fibroblast culture medium in a standard state was taken and added to the solutions of the control group (S9 solution), VC group and efficacy group respectively for cultivation. The amount of type I collagen matrix (ECM) expression was measured by fluorescence images.

[0022] Compared with before culture, the collagen matrix expres...

Embodiment 3

[0023] Embodiment 3 human body test

[0024] Select 20 women aged 40-70, record their facial skin color, fine lines, spots, dark circles, etc., and take 1 oral tablet prepared in the above-mentioned embodiment 1 every day for 8 weeks.

[0025] After 8 weeks, the improvement of the skin of the subjects was observed, in which the average skin brightness increased by 25.9%, age spots decreased by 19.2%, dark circles decreased by 19.2%, and skin wrinkles decreased by 11.7%. It shows that the composition has the functions of skin whitening and anti-wrinkle and light spot.

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PUM

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Abstract

The invention relates to a composition helpful for skin whitening and wrinkle removal. The composition comprises the following components, by weight: 5.2-42 parts of muskmelon concentrated powder, 10-25 parts of zinc-enriched yeast powder, 0-10 parts of acerola cherry powder, 0-10 parts of sea buckthorn fruit powder, 0-5 parts of aronia concentrated juice powder, 0-5 parts of licorice roots, 0-5 parts of lycopene and 30-66 parts of auxiliary materials; and the auxiliary material is more than one of isomaltitol, sorbitol, microcrystalline cellulose, silicon dioxide and magnesium stearate.

Description

Technical field: [0001] The present invention relates to a composition for skin whitening and wrinkle reduction. Background technique: [0002] In recent years, under the impetus of the "beauty economy", skin care, make-up, oral beauty and other beauty-related categories have received increasing attention from consumers, driving trillions of consumption growth in related markets. [0003] In the Asian market, "whiteness" always ranks first, and "whitening" has always been a constant theme in the beauty market, with huge market demand. Traditional whitening methods such as physical masking, scrub exfoliation, fruit acid corrosion, etc., have been difficult to gain market growth, especially some whitening skin care products that use chemical substances, such as mercury salts with whitening effects and hydroquinone with freckle removal effects Although it can quickly whiten the symptoms in a short period of time, long-term use can cause contact dermatitis or cause permanent de...

Claims

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Application Information

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IPC IPC(8): A61K36/736A61K36/87A61K9/20A61P17/16A61P17/18A61K31/01A61K31/375A61K33/30
CPCA61K36/42A61K36/064A61K33/30A61K36/736A61K36/185A61K36/73A61K36/484A61K31/01A61K36/87A61K31/375A61K9/2054A61K9/0053A61P17/16A61P17/18A61K2300/00
Inventor 梁山露
Owner 上海楷达生物科技有限公司
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