Bilberry lutein soft capsules and preparation method thereof
A technology of citrus lutein and soft capsule, applied in the field of bilberry lutein soft capsule and its preparation, can solve problems such as difficulty in disintegrating the soft capsule, reduce cross-linking reaction, etc. quality effect
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[0026] (1) Accurately weigh each raw material of required mass parts, as shown in Table 1:
[0027] Table 1
[0028]
[0029]
[0030] (2) gelatin, glycerin and purified water of required mass parts are put into chemical glue tank;
[0031] (3) Heat 50% of the soybean oil weighed in step (1), add white beeswax to dissolve, add another 50% soybean oil, stir, add other raw materials weighed in step (1), stir evenly, grind, spare;
[0032] (4) Press the ground suspension content obtained in step (3) on a pill press machine to prepare soft capsules, use a 10# olive-shaped mold to press pills, the specification is 350mg / grain, and the thickness of the rubber is 0.85mm;
[0033] (5) Dry the soft capsule pressed in step (4) and collect the pills to obtain the bilberry lutein soft capsule, the hardness of the collected pills is 2000g.
experiment example
[0047] Accelerated experiment investigates the disintegration time limit of the soft capsule that embodiment 1-8 and comparative example 1-6 make, and result is as shown in table 2:
[0048] Table 2
[0049]
[0050]Conclusion: The Bilberry Lutein Soft Capsules prepared under the formula of this application showed a good disintegration time limit in the 3-month accelerated test, and the production process was smooth; when the L-cysteine component in the formula was removed , long-term storage will lead to prolongation of the disintegration time limit of the soft capsule, and when excessive L-cysteine is added, it will lead to a large amount of solid powder during the production process, difficulty in stirring and dispersing, and grinding at the end There are more solid residues, long grinding time, and low production efficiency; when L-cysteine is replaced by other similar components, the disintegration time limit of soft capsules stored for a long time is prolonged; ...
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