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Saffron crocus petal refined alcohol extract, and preparation method and application thereof

A technology of saffron and alcohol extract, applied in application, food ingredients containing natural extract, food science and other directions, can solve the problems of lack of active ingredient extraction process, insignificant effect, low extraction rate of active ingredient, etc., and achieves hypolipidemic activity. , high extraction rate, high activity effect

Inactive Publication Date: 2021-08-27
上海中医药大学附属岳阳中西医结合医院崇明分院上海市崇明区第三人民医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Fortunately, many scholars have shifted their attention to the petals of saffron, and the research results show that although the chemical composition of the style and perianth are different, but in It has similar effects in scavenging free radicals, lowering blood pressure, and treating depression
However, the extraction process of its active ingredients is still lacking, the extraction rate of active ingredients is low, and the effect is not significant

Method used

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  • Saffron crocus petal refined alcohol extract, and preparation method and application thereof
  • Saffron crocus petal refined alcohol extract, and preparation method and application thereof

Examples

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preparation example Construction

[0032] A preparation method for the refined ethanol extract of saffron petals, comprising the steps of:

[0033] S1. Low temperature plasma treatment:

[0034] Pick fresh saffron petals and place them in cold plasma treatment equipment for cold plasma treatment. The control dose is 120-200W, and the treatment time is 15-25s. After completion, take out the saffron petals for later use;

[0035] S2. Cryogenic treatment:

[0036] The saffron petals after the low-temperature plasma treatment in step S1 are placed in liquid nitrogen for cryogenic treatment;

[0037] S3, superfine pulverization treatment:

[0038] After taking out the saffron petals after the cryogenic treatment in step S2, immediately place them in an ultrafine pulverizer for ultrafine pulverization treatment, and obtain saffron petal powder for subsequent use after completion;

[0039] S4, low temperature vacuum drying treatment:

[0040] Place the saffron petal powder obtained after the superfine pulverizatio...

Embodiment 1

[0049] A preparation method for the refined ethanol extract of saffron petals, comprising the steps of:

[0050] S1. Low temperature plasma treatment:

[0051]Pick fresh saffron petals and place them in cold plasma treatment equipment for cold plasma treatment. The control dose is 120W, and the treatment time is 15s. After completion, take out the saffron petals for later use;

[0052] S2. Cryogenic treatment:

[0053] The saffron petals after the low-temperature plasma treatment in step S1 are placed in liquid nitrogen for cryogenic treatment;

[0054] S3, superfine pulverization treatment:

[0055] After taking out the saffron petals after the cryogenic treatment in step S2, immediately place them in an ultrafine pulverizer for ultrafine pulverization treatment, and obtain saffron petal powder for subsequent use after completion;

[0056] S4, low temperature vacuum drying treatment:

[0057] Place the saffron petal powder obtained after the superfine pulverization proces...

Embodiment 2

[0065] A preparation method for the refined ethanol extract of saffron petals, comprising the steps of:

[0066] S1. Low temperature plasma treatment:

[0067] Pick fresh saffron petals and place them in cold plasma treatment equipment for cold plasma treatment. The control dose is 160W, and the treatment time is 20s. After completion, take out the saffron petals for later use;

[0068] S2. Cryogenic treatment:

[0069] The saffron petals after the low-temperature plasma treatment in step S1 are placed in liquid nitrogen for cryogenic treatment;

[0070] S3, superfine pulverization treatment:

[0071] After taking out the saffron petals after the cryogenic treatment in step S2, immediately place them in an ultrafine pulverizer for ultrafine pulverization treatment, and obtain saffron petal powder for subsequent use after completion;

[0072] S4, low temperature vacuum drying treatment:

[0073] Place the saffron petal powder obtained after the superfine pulverization proce...

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Abstract

The invention discloses a saffron crocus petal refined alcohol extract, and a preparation method and application thereof, and belongs to the technical field of saffron crocus active ingredient extraction. The preparation method comprises the following steps: S1, carrying out low-temperature plasma treatment; S2, carrying out subzero treatment; S3, carrying out superfine grinding treatment; S4, performing low-temperature vacuum drying treatment; S5, carrying out primary alcohol extraction; S6, carrying out secondary alcohol extraction; and S7, carrying out purification treatment. According to the saffron crocus petal refined alcohol extract, and the preparation method and application thereof provided by the invention, after the prepared saffron crocus petal refined alcohol extract is subjected to intragastric administration on a mouse, the weight increment and the food intake of the mouse are not remarkably different from those of a normal control group; therefore, the saffron crocus petal refined alcohol extract prepared by the method provided by the invention has relatively low influence on the appetite of the mouse and relatively small stimulation on the digestive system of the mouse. The saffron crocus petal refined alcohol extract prepared by the method disclosed by the invention has obvious blood fat reducing activity, that is, the saffron crocus petal refined alcohol extract prepared by the method disclosed by the invention is high in extraction rate and relatively high in activity.

Description

technical field [0001] The invention belongs to the technical field of extracting active components of saffron, and in particular relates to a refined ethanol extract of saffron petals, a preparation method and application thereof. Background technique [0002] Saffron, also known as saffron, saffron, tearful blue, Safaji, is a perennial herb of the genus Saffron in the Iridaceae family. It is a native species in Southwest Asia. It was introduced into China during the Ming Dynasty and was first cultivated by the Greeks. , mainly distributed in Europe, the Mediterranean and Central Asia. According to "The Pharmacopoeia of the Republic of China", its medicinal part is dry style, and as a traditional Chinese medicine, saffron has the following effects: promoting blood circulation and dispelling madness, cooling blood and detoxifying, relieving stagnation and calming the nerves. It is used for meridian pain and tumor, postpartum madness, hot toxin rash, depression and sores, fr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61K8/9794A23L33/105A61P3/06A61Q19/00A61K133/00
CPCA23V2002/00A61K36/88A61K2236/10A61K2236/17A61K2236/333A61K2236/39A61K2236/55A61K2800/805A61Q19/00A23L33/105A61K8/9794A61P3/06A23V2200/3262A23V2250/21
Inventor 王衍鸿
Owner 上海中医药大学附属岳阳中西医结合医院崇明分院上海市崇明区第三人民医院
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