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Green liquid adhesive bandage with antibacterial function and preparation method thereof

A liquid band-aid and functional technology, applied in medical science, bandages, etc., can solve the problems of bacteriostatic effect being easily affected by interfering substances, the antibacterial time of antibacterial agents is not long, and the bleeding cannot be stopped quickly, so as to be conducive to wound healing, Rapid film formation for skin irritation and no odor

Inactive Publication Date: 2021-08-24
ZHENDE MEDICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The existing liquid bandages have the following problems: the antibacterial agent has a short antibacterial time; the antibacterial effect is easily affected by interfering substances (such as blood, mucus); it is easy to produce drug resistance; it is not environmentally friendly and requires a large amount of organic solvents; Hemostasis; smelly, etc.

Method used

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  • Green liquid adhesive bandage with antibacterial function and preparation method thereof
  • Green liquid adhesive bandage with antibacterial function and preparation method thereof
  • Green liquid adhesive bandage with antibacterial function and preparation method thereof

Examples

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preparation example Construction

[0029] As a kind of embodiment, a kind of preparation method of the liquid bandage with antibacterial function of green, comprises the steps:

[0030] Step 1, prepare materials according to the formula,

[0031] According to mass percentage, the formula includes: 10-40% of film-forming agent, 0.1-3% of octenidine, 0.2-20% of moisturizing agent, 0.1-5% of wound healing promoting substance, 0.01-0.03% of coagulation factor, and 31.9-84.7% of water %; the film-forming agent comprises: 3-13% of polyvinyl alcohol, 3-13% of polyvinylpyrrolidone, and 4-14% of polyvinyl butyral according to mass percentage;

[0032] Step 2, adding the film-forming agent into water, and then heating to 50-80°C until completely dissolved;

[0033] Step 3, adding octenidine into the solution to control the temperature at 30-50°C and stirring for 20-30 minutes;

[0034] Step 4, add the moisturizing agent into the solution, control the temperature at 20-40°C, and stir for 10-20 minutes;

[0035] Step fi...

Embodiment 1

[0038] Embodiment 1: film forming agent 1 polyvinyl alcohol 3%, film forming agent 2 polyvinyl pyrrolidone 3%, film forming agent 3 polyvinyl butyral 4%, octenidine 0.1%, glycerin 0.1%, hyaluronic acid Sodium phosphate 0.1%, centella asiatica extract 5%, coagulation factor 0.02%, water 84.7%;

Embodiment 2

[0039] Embodiment 2: film forming agent 1 polyvinyl alcohol 8%, film forming agent 2 polyvinyl pyrrolidone 8%, film forming agent 3 polyvinyl butyral 9%, octenidine 1.5%, glycerin 10%, hyaluronic acid Sodium acid 0.2%, centella asiatica extract 2.5%, coagulation factor 0.01%, water 60.8%.

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Abstract

The invention discloses a green liquid adhesive bandage with an antibacterial function and a preparation method thereof. The formula of the liquid adhesive bandage comprises the following components in percentage by mass: 10-40% of a film-forming agent, 0.1-3% of octenidine, 0.2-20% of a humectant, 0.1-5% of a wound healing promoting substance, 0.01-0.03% of a blood coagulation factor and 31.9-84.7% of water, the film-forming agent is prepared from the following components in percentage by mass: 3 to 13 percent of polyvinyl alcohol, 3 to 13 percent of polyvinylpyrrolidone and 4 to 14 percent of polyvinyl butyral; the product prepared according to the formula and the method has the advantages of being good in antibacterial effect, fast in film forming, small in skin irritation, fast in hemostasis, fast in wound healing, free of peculiar smell and the like.

Description

technical field [0001] The invention relates to the field of medical materials, in particular to a green liquid bandage with antibacterial function and a preparation method thereof. Background technique [0002] Liquid Band-Aid is a new type of Band-Aid that has emerged in recent years and is different from traditional Band-Aids. Traditional Band-Aids are strips of adhesive tape with a strip of gauze in the middle. The liquid band-aid is a solvent contained in a small bottle, which is a biofilm-forming disinfectant. It combines the continuous disinfection function of the wound surface with the continuous protection function of the wound surface, and has good waterproof performance (it will not penetrate directly in contact with water). And it can effectively kill Escherichia coli, Staphylococcus aureus and Candida albicans; the elastic transparent film formed has a wound protection effect with good air permeability. Compared with traditional Band-Aids, liquid Band-Aids di...

Claims

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Application Information

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IPC IPC(8): A61L26/00
CPCA61L26/0066A61L26/0014A61L26/0057A61L26/0047A61L2300/404A61L2300/412A61L2300/418A61L2300/216A61L2300/30A61L2300/414C08L29/04C08L39/06C08L29/14
Inventor 张龙军鲁建国徐达李玉红
Owner ZHENDE MEDICAL CO LTD
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