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Composition for improving quality of milk, and preparation method and applications thereof

A technology for composition and milk quality, applied in the directions of drug combination, pharmaceutical formula, drug delivery, etc., can solve problems such as unsolved problems, and achieve the effect of reducing the number of milk somatic cells and improving milk quality

Inactive Publication Date: 2021-02-19
CHINA AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In recent years, although the research and application of melatonin in the dairy industry has been reported, there are still some limitations, and many problems have not yet been resolved

Method used

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  • Composition for improving quality of milk, and preparation method and applications thereof
  • Composition for improving quality of milk, and preparation method and applications thereof
  • Composition for improving quality of milk, and preparation method and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] Embodiment 1 melatonin injection preparation method

[0055] Raw materials: melatonin, absolute ethanol;

[0056] Preparation method: accurately weigh 464.54mg of melatonin, dissolve it in a 100mL volumetric flask with absolute ethanol, stir evenly, then add 0.9% normal saline, stir evenly, and set the volume to 100mL (absolute ethanol: normal saline=3: 2), and finally dispensed into 2mL injection doses, and all operations were completed in a dark room.

Embodiment 2

[0057]Example 2 Analysis of subcutaneous injection of melatonin on milk DHI index

[0058] 1. Experimental method

[0059] (1) According to the monthly dairy farm DHI test report, select Holstein cows with a somatic cell count of 300,000 / mL to 1 million / mL and feed them separately, ensuring that there is no significant difference in health and health. Seasonal group: n=90 in spring, n=74 in summer, n=83 in autumn, n=81 in winter (the first time). Age group: 2 years old n=23; 3 years old n=80; 4 years old n=66; 5 years old n=56; 6 years old n=27; 7 years old n=19 (for the first time). Lactation group: peak lactation n=15, mid lactation n=38, late lactation n=59 (first time) (early lactation: 1-15 days after calving; peak lactation: 16-100 days; mid-lactation: 101-200 days; end of lactation: 201 days-stop milk).

[0060] (2) In the high somatic cell count dairy herd, select 4 days a month, continuously inject 2 mL of melatonin solution, and take fresh milk after 15 days, stor...

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Abstract

The invention discloses a composition containing melatonin as an active ingredient and applications of the composition in enhancing the production performance of DHI and improving the quality of milk.The composition can significantly reduce somatic cell count in milk and improve the quality of the milk. Under conditions of different seasons, ages and lactation periods, the somatic cell score (p <0.01) of the milk can be significantly decreased by applying the composition; the protein content and lactose content in the milk can be increased; and the fat content and urea nitrogen content in the milk can be reduced. Thus, the composition can improve the quality of the milk and enhance the benefits of dairy farming.

Description

technical field [0001] The invention relates to the field of animal husbandry and veterinary medicine, in particular to a composition for improving milk quality, a preparation method and application thereof. Background technique [0002] With the rapid development of economy and society, people's demand for dairy products is gradually increasing, and the dairy farming industry is showing a trend of rapid development. However, due to the late start of my country's dairy farming industry, high breeding costs and poor management experience restrict the development of the industry. The application of Dairy Herd Improvement (DHI) to improve the performance of dairy cows and improve breeding efficiency is an important means of pasture management. In DHI data, somatic cell count, lactose, milk fat, and milk protein are all important indicators for determining milk quality. The DHI index is affected by many factors, and there are differences in the DHI index of dairy cows in diffe...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K31/4045A61K47/02A61P3/00A61P15/14A01K67/02
CPCA61K31/4045A61K9/0019A61K9/08A61K47/02A61P15/14A61P3/00A01K67/02
Inventor 刘国世吴昊路永强张鲁马慧常毅刘巧香姚松阳姬鹏云
Owner CHINA AGRI UNIV
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