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Human organ blood oxygenation system

A blood oxygenation and human organ technology, applied in the field of blood oxygenation system of human organs, can solve the problems of low degree, inability to remove toxins, and inability to effectively preserve severed limbs for a long time, so as to reduce pain and save medical costs , high clinical application value and social benefits

Active Publication Date: 2021-07-30
BEIJING SHIJITAN HOSPITAL CAPITAL MEDICAL UNIVERSTY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, traditional mechanical perfusion systems mimic physiological conditions to a lesser extent
[0007] In recent years, a large number of studies have used low temperature combined with organ perfusion fluid to preserve severed limbs, and achieved good results, but they cannot effectively preserve severed limbs for a long time, nor can they remove a large amount of toxins produced by tissue necrosis of severed limbs before replantation

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] Example 1 A human organ blood oxygenation system

[0065] like figure 1 As shown, the blood oxygenation system of human organs includes extracorporeal circulation transfers 1 and 5, membrane oxygenator 2, gas generator or cylinder 3, blood storage device 4, blood purification device 6, replacement fluid 7, and extracorporeal circulation circuit 8. Its working process: the venous blood of the human body is drained from the extracorporeal circulation line 8 to the blood storage device 4, and the oxygen in a special ratio is passed through the membrane oxygenator 2 to oxygenate the venous blood by using the gas generator or the gas cylinder 3, and then the Extracorporeal circulation transitions 1 and 5 drive the blood to undergo extracorporeal circulation, and the oxygenated blood will undergo ion exchange with a specially proportioned replacement fluid 7 in the blood purification device 6, and finally enter the human arterial system. Circulating blood will monitor tempe...

Embodiment 2

[0070] Example 2 A human organ blood oxygenation system

[0071] like figure 2 As shown, the blood oxygenation system of human organs includes extracorporeal circulation transfer 2-1, membrane oxygenator 2-2, blood purification device 2-3, sterile table 2-4, heparin pump 2-5, blood pressure sensor 2 -6, temperature control device 2-7. Extracorporeal circulation turning machine 2-1 is a centrifugal pump, which provides power for blood circulation, ensures continuous extracorporeal blood perfusion, and reduces the number of damaged red blood cells. The membrane oxygenator 2-2 is a membrane lung, which plays a part of cardiopulmonary replacement and maintains the oxygenation of limb tissues. The blood purification device 2-3 filters the inflammatory media and metabolic waste in the extracorporeal circulation blood to purify the blood. Sterile bench 2-4: Provide a sterile environment. Heparin pumps 2-5 continuously pump heparin into the circulation to prevent blood clotting. ...

Embodiment 3

[0076] Example 3 A human organ blood oxygenation system

[0077] like image 3 As shown, the human physiological data monitoring and detection device, such as the automatic blood gas detection device 3-1 and the automatic biochemical detection device 3-2, can detect PH, electrolyte, lactic acid, urea, creatinine, etc. in the circulating fluid, when the automatic blood gas detection device 3- 1 and the automatic biochemical detection device 3-2 detect that the above-mentioned value is too high or too low, through an intelligent remote control device such as an automatic detection control system 3-0, mobilize the gas regulating device 3-14 to adjust the blood gas of the circulating fluid, and mobilize the ion regulation Device 3-15, for preliminary correction of the ion level in the circulating fluid. The circulating fluid passes through the blood purification device such as the filter device 3-3, adjusts the ratio and flow rate of the replacement fluid to automatically correct...

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Abstract

The invention provides a blood oxygenation system for human organs, the system includes an extracorporeal circulation switch, a membrane oxygenator, and a blood purification device, wherein the extracorporeal circulation switch is used to replace the heart pumping blood, and the membrane oxygenator is used to replace lung oxygenation , the blood purification device is used to replace part of the liver and kidney functions; the blood oxygenation system of human organs drives human venous blood through extracorporeal circulation, oxygenates in the membrane oxygenator, and is drained to the blood purification device for ion exchange with the replacement fluid. Finally, it is perfused into the blood circulation system of human tissues to establish local blood circulation. The system improves the viability of the tissue by oxygenating the venous blood of human organs, and uses the extracorporeal blood purification device to neutralize the toxins produced before the replantation of the amputated limb, reducing toxic shock and acute renal failure after replantation It can also be used for one or more of lung diseases, including but not limited to infectious lung diseases, such as the rescue of new coronary pneumonia.

Description

technical field [0001] The invention relates to a maintenance system of human organs, in particular to a blood oxygenation system of human organs. Background technique [0002] Respiratory support therapy is the main treatment for respiratory failure. High-flow nasal cannula oxygen therapy or non-invasive mechanical ventilation is often ineffective, and invasive mechanical ventilation cannot solve the problem in critical cases. [0003] The shortage of donors in heart and lung transplantation has always been a bottleneck in the advancement of transplantation technology. Many patients who need organ transplantation have to wait for a long time for the appearance of a donor, and most patients eventually die because they cannot wait for a donor. [0004] The incidence of malignant tumors is increasing year by year. Chemotherapy is one of the main methods for the treatment of malignant tumors. Although high-dose chemotherapy can significantly kill tumor cells, it also has non-ne...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N1/02
CPCA01N1/0247
Inventor 王江宁
Owner BEIJING SHIJITAN HOSPITAL CAPITAL MEDICAL UNIVERSTY
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