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Mosquito-repellent, itching-relieving and swelling-alleviating external gel and preparation method thereof

A gel for external use, a technology for relieving itching and swelling, which is applied in the directions of non-central analgesics, medical preparations without active ingredients, and medical preparations containing active ingredients, etc. Affect portability and other issues

Pending Publication Date: 2020-10-27
KUNMING MEDICAL UNIVERSITY +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, Wanjin fragrance aerosol must be packaged in a sealed "aluminum tube + projectile valve", which is bulky and affects portability, and the production process is complicated and the cost is high; there is a propellant in the aerosol tank, and the pressure inside the tank is relatively high. High, there is a risk of explosion when heated or impacted, and there is also the possibility of propellant leakage and failure; as a topical product for mosquito bites, the aerosol spray covers a large area when used, and the dosage is difficult to control , and easy to contaminate clothes; use ethanol as a solvent, which is more irritating to the skin and is not suitable for facial use

Method used

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  • Mosquito-repellent, itching-relieving and swelling-alleviating external gel and preparation method thereof
  • Mosquito-repellent, itching-relieving and swelling-alleviating external gel and preparation method thereof
  • Mosquito-repellent, itching-relieving and swelling-alleviating external gel and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0059] Example 1 Preparation

[0060] This embodiment discloses the preparation method of the external mosquito repellent, antipruritic and detumescence gel of the present invention, and its raw material formula is:

[0061] Aina sesame oil 70 parts, eucalyptol 20 parts, menthol 20 parts, glycerin 900 parts, triethanolamine 70 parts, carbomer type C 190 parts, edetate disodium 20 parts.

[0062] Its preparation method is:

[0063] Step 1. Preparation of carbomer solution: Add carbomer C type with 42.5 times the mass of water, homogenize for 10 minutes, and vacuum defoam for about 1 hour to obtain carbomer solution;

[0064] Step 2. Prepare menthol solution: add menthol to 37.5 times the mass of absolute ethanol to dissolve to prepare menthol solution;

[0065] Step 3. Add Aina sesame oil, eucalyptol, glycerin, and disodium edetate to the carbomer solution, stir for 10 minutes, then add menthol solution, stir for 10 minutes, make it mix evenly, and then add three Stir ethano...

Embodiment 2

[0067] Embodiment 2 preparation example

[0068] This example discloses the preparation method of the external mosquito repelling, antipruritic and detumescence gel of the present invention, its raw material formula is: 20 parts of Aina sesame oil, 50 parts of lavender oil, 20 parts of eucalyptol, 20 parts of menthol, 500 parts of glycerin, 100 parts of aloe vera freeze-dried powder, 300 parts of propylene glycol, 70 parts of triethanolamine, 70 parts of carbomer type C, 120 parts of xanthan gum, and 20 parts of disodium edetate.

[0069] Its preparation method is:

[0070] Step 1. Prepare a thickener solution: take Carbomer Type C and xanthan gum, add water 30 times the mass of the total amount, homogenize for 20 minutes, vacuumize and defoam for about 1 hour, and obtain a thickener solution;

[0071] Step 2. Prepare menthol solution: add menthol to 40 times the mass of 70% ethanol to dissolve to prepare menthol solution;

[0072] Step 3. Add Aina sesame oil, lavender oil, ...

Embodiment 3

[0074] Embodiment 3 preparation example

[0075] This example discloses the preparation method of the external mosquito repelling, antipruritic and detumescence gel of the present invention, its raw material formula is: 10 parts of Aina sesame oil, 15 parts of lavender oil, 40 parts of eucalyptol, 10 parts of menthol, 800 parts of glycerin, 300 parts of aloe vera freeze-dried powder, 400 parts of propylene glycol, 30 parts of triethanolamine, 70 parts of carbomer type C, and 10 parts of disodium edetate.

[0076] Its preparation method is:

[0077] Step 1. Preparation of thickener solution: Take Carbomer Type C, add 120 times the mass of water, homogenize for 20 minutes, and vacuum defoam for about 1 hour to obtain thickener solution;

[0078] Step 2. Prepare menthol solution: add menthol to 30 times the mass of 60% ethanol to dissolve to prepare menthol solution;

[0079] Step 3. Add Aina sesame oil, lavender oil, eucalyptol, glycerin, aloe vera freeze-dried powder, propyle...

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Abstract

The present invention provides a mosquito-repellent, itching-relieving and swelling-alleviating external gel. The mosquito-repellent, itching-relieving and swelling-alleviating external gel comprisesthe following raw material components in parts by weight: 1-10 parts of blumea balsamifera oil, 1-4 parts of cineole, 1-4 parts of menthol, 8-50 parts of a moisturizing agent and 5-30 parts of a thickener. The present invention also provides a preparation method and an application of the gel, and an itching-relieving composition containing the gel. The national medicinal plant blumea balsamifera extract is combined with a stable gel matrix, can effectively relieve itching, and has characteristics of skin moisturizing, no skin irritation, and non-toxic oral administration.

Description

technical field [0001] The present application relates to a gel for external use, in particular to an external gel for repelling mosquitoes, relieving itching and reducing swelling. Background technique [0002] Mosquitoes are rampant in summer, and children are more vulnerable to mosquito bites. Because children's skin is relatively tender, they respond strongly to external stimuli. Once bitten, they will quickly appear red and swollen, and even blisters will appear in serious cases. In addition, the itching is unbearable, and it will cause infection due to scratching. At present, wind essential oil products on the market belong to over-the-counter drugs and can only be purchased in pharmacies. They are mainly composed of menthol, eucalyptus oil, clove powder, camphor, sesame oil, etc., and have fast onset of antipruritic effect, but the ingredients contain camphor, which is not suitable for There are taboos for infants and young children; toilet water products are non-spe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/28A61K36/53A61K9/06A61K47/32A61K47/36A61P17/00A61P17/04A61P29/00A61K31/045A61K31/35
CPCA61K31/045A61K36/53A61K31/35A61K36/28A61K9/06A61K9/0014A61K47/36A61K47/32A61P29/00A61P17/04A61P17/00
Inventor 陈真柴立陆地韩毅李霞贾金艳
Owner KUNMING MEDICAL UNIVERSITY
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