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A kind of Ganoderma lucidum dendrobium suspension and preparation method thereof

A technology of dendrobium candidum and suspension, which is applied in the direction of anti-toxic agents, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problems of affecting pharmacological effects, affecting the spatial structure of polysaccharides, and the variability and inactivation of polysaccharides. Effects of time, extended shelf life, and diffusion retardation

Active Publication Date: 2021-08-10
福建仙芝楼生物科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the microwave in the microwave drying method will affect the spatial structure of polysaccharides as high temperature, and make the polysaccharides of Ganoderma lucidum and Dendrobium officinale polysaccharides unstable and inactivated, which affects the pharmacological effects.

Method used

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  • A kind of Ganoderma lucidum dendrobium suspension and preparation method thereof
  • A kind of Ganoderma lucidum dendrobium suspension and preparation method thereof
  • A kind of Ganoderma lucidum dendrobium suspension and preparation method thereof

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preparation example Construction

[0032] Preparation of Ganoderma lucidum extract powder: Harvest mature Ganoderma lucidum, wash and dry, control the water content below 3%, crush it into particles of about 10 mesh, and use supercritical CO 2 Extraction technology to remove fat-soluble impurities, extraction pressure 25MPa, temperature 40°C, separation pressure 6MPa, temperature 45°C, CO 2 The flow rate is 600L / hr, add 12 times of 95% edible alcohol, stir and extract at 85°C for 2 hours to obtain the primary extract, add 10 times of 95% edible alcohol to extract for 2 hours, combine the secondary extracts, concentrate and dry, and ultrafinely pulverize to obtain Ganoderma lucidum Extract powder, the particle size of Ganoderma lucidum extract powder is 5-10 μm, and the content of Ganoderma lucidum triterpene acid is ≥15%;

[0033] Preparation of Dendrobium candidum extract: Harvest mature fresh strips of Dendrobium candidum, cut into sections, freeze-dry, control the water content below 3%, crush into 10-20 mes...

Embodiment 1

[0036] Preparation of Ganoderma lucidum extract powder: Harvest mature Ganoderma lucidum, wash and dry, control the water content below 3%, crush it into particles of about 10 mesh, and use supercritical CO 2 Extraction technology to remove fat-soluble impurities, extraction pressure 25MPa, temperature 40°C, separation pressure 6MPa, temperature 45°C, CO 2 The flow rate is 600L / hr, take 100kg of defatted granules, add 1200kg of 95% edible alcohol, stir and extract at 85°C for 2 hours to obtain the primary extract, then add 1000kg of 95% edible alcohol to extract for 2 hours, combine the secondary extract, concentrate and dry, and ultrafinely pulverize , to obtain about 5kg of Ganoderma lucidum extract powder, the particle size of the Ganoderma lucidum extract powder is 5-10 μm, and the content of Ganoderma lucidum triterpene acid is 15.9%;

[0037] Preparation of Dendrobium candidum extract: Harvest mature fresh strips of Dendrobium candidum, cut into sections, freeze-dry, con...

Embodiment 2

[0040] Preparation of Ganoderma lucidum extract powder: Harvest mature Ganoderma lucidum, wash and dry, control the water content below 3%, crush it into particles of about 10 mesh, and use supercritical CO 2 Extraction technology to remove fat-soluble impurities, extraction pressure 25MPa, temperature 40°C, separation pressure 6MPa, temperature 45°C, CO 2 The flow rate is 600L / hr, take 100kg of defatted granules, add 1200kg of 95% edible alcohol, stir and extract at 85°C for 2 hours to obtain the primary extract, then add 1000kg of 95% edible alcohol to extract for 2 hours, combine the secondary extract, concentrate and dry, and ultrafinely pulverize , to obtain about 5kg of Ganoderma lucidum extract powder, the particle size of the Ganoderma lucidum extract powder is 5-10 μm, and the content of Ganoderma lucidum triterpene acid is 15.9%;

[0041] Preparation of Dendrobium candidum extract: Harvest mature fresh strips of Dendrobium candidum, cut into sections, freeze-dry, con...

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Abstract

A Ganoderma lucidum dendrobium suspension and a preparation method thereof. A ganoderma dendrobium suspension, the mass percentage of each component is: 20-30% of ganoderma extract powder, 65-75% of dendrobium candidum extract, 4.98-4.99% of water, 0.01-0.02% of sweetener, the The preparation method of the suspension: Ganoderma lucidum fruiting body pulverization, supercritical CO 2 Extract to remove fat-soluble impurities, extract with ethanol, filter, concentrate and dry and ultrafinely pulverize to obtain Ganoderma lucidum extract powder; freeze-dry Dendrobium candidum, extract at low temperature, and centrifuge the extract to obtain Dendrobium candidum extract; Ganoderma lucidum extract powder Suspending with Dendrobium candidum extract, dissolving the sweetener in water, mixing the water with the suspension, and aseptically filling to obtain a finished product. The content of Ganoderma lucidum triterpene acid in the finished product is ≥30mg / mL, and the content of polysaccharides is ≥35mg / mL. The invention uses Ganoderma lucidum as the functional component and antibacterial agent, and Dendrobium candidum as the functional component, suspending agent and corrective agent, and the finished product has good stability, good taste and no bitter taste.

Description

technical field [0001] The invention belongs to the fields of extraction and separation of natural products, health food and preparations, in particular to a Ganoderma lucidum dendrobium suspension and a preparation method thereof. Background technique [0002] Ganoderma lucidum (Leyss.ex Fr.) Karst.) is a kind of Ganoderma lucidum in Polyporaceae fungus (Chinese Pharmacopoeia 2015 edition one), sweet in taste and flat in nature, strengthening the body, and the main active ingredients are Ganoderma lucidum triterpenoids and Ganoderma lucidum polysaccharides , Ganoderma lucidum triterpenoids have various pharmacological effects such as anti-oxidation, regulating immunity, anti-tumor, protecting the liver, lowering blood sugar and inhibiting bacteria. The content of Ganoderma lucidum triterpenoids in Ganoderma lucidum fruiting body is extremely low, accounting for about 0.5-1% of the dry fruiting body weight, and it is difficult to dissolve in water, generally made into capsul...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8984A61K36/074A61K9/10A61P35/00A61P37/02A61P39/06A61P31/00A61P1/14A23L33/105
CPCA23V2002/00A61K9/10A61K36/074A61K36/8984A61K2236/331A61K2236/333A61K2236/37A23L33/105A61P1/14A61P31/00A61P35/00A61P37/02A61P39/06A61K2300/00A23V2200/308A23V2200/324A23V2200/32A23V2200/30A23V2250/208A23V2250/21
Inventor 周岩飞李晔陈桂秋林真吴长辉姚渭溪
Owner 福建仙芝楼生物科技有限公司
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