Compound indometacin and dyclonine paste with waterproof performance and preparation method of compound indometacin and dyclonine paste

A compound and indole technology, applied in the field of medical supplies, can solve the problems of easy adhesion and poor waterproof performance of the plaster surface, and achieve the effect of clean and beautiful appearance, not easy to adhere, and strong anti-fouling ability

Active Publication Date: 2020-06-19
杭州仁德药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The present invention aims to overcome the problems of poor waterproof performance in plasters and easy adhesion of dirty stains on the plaster surface, etc., and provides a compound indomethacin and daclonine plaster with waterproof performance and a preparation method thereof. Domethacin dacronin plaster has strong surface hydrophobicity, is not easy to be attached by dirty stains, and has strong waterproof and antifouling ability

Method used

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  • Compound indometacin and dyclonine paste with waterproof performance and preparation method of compound indometacin and dyclonine paste

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] A compound indomethacin-dacronine plaster with waterproof properties, the compound indomethacin-dacronine plaster sequentially includes a waterproof layer, a base cloth layer and a plaster layer, and the waterproof layer includes a first waterproof layer and the second waterproof layer, the first waterproof layer and the second waterproof layer are distributed on both sides of the base cloth layer, the second waterproof layer is between the base cloth layer and the plaster layer, and the waterproof layer is a super-hydrophobic surface layer, The plaster layer is a traditional Chinese medicine coating layer, and the base cloth layer is non-woven fabric.

[0040] The raw materials of the 100g traditional Chinese medicine ointment consist of: 2.5g of indomethacin, 0.2g of dyclonine hydrochloride, 8g of camphor, 4g of menthol, 30g of zinc oxide, 23g of rosin, 4g of lanolin, 4g of dimethyl sulfoxide, and the rest All are rubber.

[0041] The preparation method of described ...

Embodiment 2

[0053] The difference from Example 1 is that it is a compound indomethacin-dacronine plaster with waterproof performance, and the compound indomethacin-dacronine plaster includes a waterproof layer, a base cloth layer and a plaster layer in sequence , the waterproof layer includes a first waterproof layer and a second waterproof layer, the first waterproof layer and the second waterproof layer are distributed on both sides of the base cloth layer, the second waterproof layer is between the base cloth layer and the plaster layer, the The waterproof layer is a super-hydrophobic surface layer, the plaster layer is a traditional Chinese medicine coating layer, and the base cloth layer is non-woven fabric.

[0054] The raw materials of the 100g traditional Chinese medicine ointment consist of: 2g of indomethacin, 0.1g of dyclonine hydrochloride, 7g of camphor, 3g of menthol, 29g of zinc oxide, 22g of rosin, 3g of lanolin, 3g of dimethyl sulfoxide, and the rest are all For rubber. ...

Embodiment 3

[0067] The difference from Example 1 is that it is a compound indomethacin-dacronine plaster with waterproof performance, and the compound indomethacin-dacronine plaster includes a waterproof layer, a base cloth layer and a plaster layer in sequence , the waterproof layer includes a first waterproof layer and a second waterproof layer, the first waterproof layer and the second waterproof layer are distributed on both sides of the base cloth layer, the second waterproof layer is between the base cloth layer and the plaster layer, the The waterproof layer is a super-hydrophobic surface layer, the plaster layer is a traditional Chinese medicine coating layer, and the base cloth layer is non-woven fabric.

[0068] The raw materials of the 100g traditional Chinese medicine ointment consist of: 3g of indomethacin, 0.3g of dyclonine hydrochloride, 9g of camphor, 5g of menthol, 31g of zinc oxide, 24g of rosin, 5g of lanolin, 5g of dimethyl sulfoxide, and the rest are all For rubber. ...

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Abstract

The invention relates to the field of medical supplies and in particular relates to a compound indometacin and dyclonine paste with a waterproof performance and a preparation method of the compound indometacin and dyclonine paste. The compound indometacin and dyclonine paste sequentially includes a waterproof layer, a base cloth layer and a plaster layer, wherein the waterproof layer includes a first waterproof layer and a second waterproof layer, two sides of the base cloth layer are distributed with the first waterproof layer and the second waterproof layer, the second waterproof layer is located between the base cloth layer and the plaster layer, the waterproof layer is a superhydrophobic surface layer, the plaster layer is a traditional Chinese medicine coating layer, and the base cloth layer is a non-woven fabric. Calculated by 100%, the paste includes the components in parts by mass: 2-3 parts of indometacin, 0.1-0.3 part of dyclonine hydrochloride, 7-9 parts of camphor, 3-5 parts of menthol, 29-31 parts of zinc oxide, 22-24 parts of rosin, 3-5 parts of wool fat, 3-5 parts of dimethyl sulfoxide and the balance of rubber. The compound indometacin and dyclonine paste is relatively strong in surface hydrophobicity, not easily attached by dirty marks and relatively strong in air pollution prevention capability.

Description

technical field [0001] The invention relates to the field of medical supplies, in particular to a waterproof compound indomethacin and dacronine plaster and a preparation method thereof. Background technique [0002] The main therapeutic effect of the compound indomethacin and dacronine plaster is to treat polymyalgia rheumatica. Because the therapeutic effect of the drug is good, it is a plaster that is simple, convenient, and easy to carry, and is very popular among patients. Because it is directly attached to the skin surface during use and is in a directly exposed state, the plaster is easily soaked when it encounters water, which affects the efficacy and bonding effect, which makes people have to replace it with a new plaster. It brings great troubles to people; at the same time, dirty stains are easy to adhere to the surface of the plaster, which affects the aesthetic appearance of the plaster. [0003] Patent No. CN201510318587.5, the patent name is "Snake Oil Plaste...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/30A61K9/70A61K47/44A61K47/38A61P29/00A61P21/00A61K31/045A61K31/125A61K31/405A61K31/4453
CPCA61K9/7046A61K9/7076A61K31/045A61K31/125A61K31/405A61K31/4453A61K33/30A61P21/00A61P29/00A61K2300/00
Inventor 俞帮和徐明蒋志刚汪海涛
Owner 杭州仁德药业股份有限公司
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