Composite metal cysteamine chelate and preparation method and application thereof

A metal chelate, composite metal technology, applied in the application, animal feed, additional food elements, etc., can solve the problems of excessive zinc in feed, endangering animal health, limited long-term stability, etc., to meet growth needs and improve nutrition. Value, effect on improving stability and bacteriostatic properties

Pending Publication Date: 2020-05-05
长沙绿拓生物科技有限公司 +1
View PDF4 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, cysteamine chelated zinc also has the following defects, which limit its application in feed:
[0004] (1) The high zinc content can easily lead to excessive zinc in the feed and endanger animal health;
[0005] (2) Long-term stability is limited, affecting feed storage;
[0006] (3) Poor antibacterial properties, limited effect on preventing feed mildew and improving animal disease resistance

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Composite metal cysteamine chelate and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0018] The preparation method of the complex metal cysteamine chelate of the embodiment of the present invention comprises steps:

[0019] S1. Dissolving cysteamine hydrochloride in water, adding a metal compound, stirring evenly, adjusting the pH value to 10-11, heating for reaction, and filtering to obtain cysteamine metal chelate;

[0020] S2. Disperse the cysteamine metal chelate in ethanol to make the solution alkaline, add ethyl orthosilicate, stir until the system is cloudy, add dodecyldimethyl tertiary amine and γ-chlorine Propyltrimethoxysilane, heated for reaction, filtered, washed and dried to obtain complex metal cysteamine chelate.

[0021] This method generates SiO in situ by hydrolysis of tetraethyl orthosilicate 2 , using electrostatic adsorption to in situ deposit SiO on the outer layer of cysteamine metal chelate 2 Coating layer, and through the reaction of dodecyldimethyl tertiary amine and γ-chloropropyltrimethoxysilane to generate organosilicon quaternar...

Embodiment 1

[0038] (1) Preparation of cysteamine metal chelate. Dissolve 5g of cysteamine hydrochloride in water, stir at room temperature until cysteamine hydrochloride is completely dissolved, then add 1.6g of calcium carbonate, 2.2g of zinc sulfate heptahydrate, 0.6g of iron sulfate heptahydrate, 0.5g of pentahydrate Copper sulfate hydrate, 0.4g manganese sulfate heptahydrate, after adding each substance, stir for about 30 minutes until completely dissolved; add solid sodium hydroxide, adjust the pH value to 10, and obtain a cloudy solution; stir at 80°C for 1 hour; filter with suction , to obtain cysteamine metal chelate, dry weight about 4.6g;

[0039] (2) SiO 2 Preparation of coated cysteamine metal chelates. Add the cysteamine metal chelate (wet filter cake) prepared in step (1) to 100mL ethanol, stir for 30min until it is uniformly dispersed, test that the pH is alkaline, add 3mL tetraethyl orthosilicate, add 0.01g dispersant Tween 80, the mixed solution was stirred at room tem...

Embodiment 2

[0042] (1) Preparation of cysteamine metal chelate. Dissolve 5 g of cysteamine hydrochloride in water, add 0.1 g of dispersant polyvinylpyrrolidone, and stir at room temperature until cysteamine hydrochloride is completely dissolved; add 0.9 g of calcium oxide, 2.7 g of zinc sulfate heptahydrate, 0.86 g ferric sulfate heptahydrate, 0.4g copper sulfate pentahydrate, 0.3g manganese sulfate pentahydrate, 0.02g polyvinylpyrrolidone, after adding each substance, stir for about 30min until completely dissolved; add 35% sodium hydroxide aqueous solution , adjust the pH value to 11 to obtain a turbid solution; stir at 80°C for 1 hour; filter with suction to obtain cysteamine metal chelate, with a dry weight of about 4.75g;

[0043] (2) SiO 2 Preparation of coated cysteamine metal chelates. Add the cysteamine metal chelate (wet filter cake) prepared in step (1) to 100mL ethanol, stir for 30min until it is uniformly dispersed, test the pH to be alkaline, add 2mL tetraethyl orthosilica...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a composite metal cysteamine chelate and a preparation method and application thereof. The preparation method comprises the steps of enabling cysteamine hydrochloride to dissolve in water, adding metal salt or a metallic compound, performing uniform stirring, adjusting pH value to be 10-11, performing a heating reaction, and performing filtration so as to obtain a cysteamine metal chelate; and enabling the cysteamine metal chelate to be dispersed in ethanol, adding ethyl orthosilicate, performing stirring until a system is turbid, adding N,N-dimethyldodecylamine and (3-chloropropyl)trimethoxysilane, performing a heating reaction, performing filtration, performing washing, and performing drying so as to obtain the composite metal cysteamine chelate. A trace metal element is chelated with cysteamine, an SiO2 coating layer is subjected to in situ deposition at the outer layer of the chelate, and through cooperation with modification of quaternary ammonium salt at the surface, stability and bacterial inhibition are increased, the storage life of a feed is prolonged, mildew and rot of the feed are prevented, and the composite metal cysteamine chelate has equivalent application value.

Description

technical field [0001] The invention relates to a cysteamine complex, in particular to a complex metal cysteamine chelate, its preparation method and application. Background technique [0002] Cysteamine can be used as a feed additive, which can promote animal growth, increase feed-to-meat ratio and protein deposition rate. In order to solve the problem of poor stability of cysteamine, cysteamine hydrochloride is generally produced in practical applications, which must be dissolved in water and then mixed with feed to feed, which is inconvenient to use, and has poor palatability and bad smell and other shortcomings. [0003] Cysteamine chelated zinc is a new type of feed additive developed in recent years. The addition of zinc can promote the growth and development of animals, enhance the immunity of animals, and improve the stability of chemical structure and palatability. However, cysteamine chelated zinc also has the following defects, which limit its application in fee...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A23K20/10A23K20/20
CPCA23K20/10A23K20/20A23K20/30
Inventor 李素芳胡兰黄喜妹谭军张心怡黎梦梅宋肖
Owner 长沙绿拓生物科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap