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Degradable magnesium alloy material composed of multiple components as well as preparation method and application thereof

A magnesium alloy, multi-component technology, applied in the field of degradable magnesium alloy materials and its preparation, to achieve uniform degradation, promote bone growth, and promote antibacterial effects

Active Publication Date: 2020-04-10
SOUTHEAST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] Technical problem: The purpose of the present invention is to provide a multi-component degradable magnesium alloy material and its preparation method and application, to overcome the difficulty of a single component material for local performance and multi-functional requirements, and to achieve the mechanical properties of the material, The mutual matching between degradation rate and functionalization meets the requirements of the service environment of biomaterials on the mechanical properties, degradation rate and functionalization of magnesium alloys

Method used

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  • Degradable magnesium alloy material composed of multiple components as well as preparation method and application thereof
  • Degradable magnesium alloy material composed of multiple components as well as preparation method and application thereof
  • Degradable magnesium alloy material composed of multiple components as well as preparation method and application thereof

Examples

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Effect test

Embodiment 1

[0029] A degradable magnesium alloy material composed of multiple components, which is used to prepare cortical bone screws with multiple components (such as figure 2 As shown), according to actual needs, the bone screw body is wrapped inside the bone tissue, the strength of the screw thread needs to be increased, the toughness of the screw body must be improved, and the stress corrosion resistance must be improved, and it can also release the growth-promoting bone tissue Elements; because the nail head is in contact with soft tissue, under the premise of ensuring the required strength of the material, it is necessary to improve the corrosion resistance; in order to have a better fixing effect, it should also have a certain antibacterial ability. Therefore, the determined element requirements are: Mg, Zn, Zr, Cu, Mn, Sr, Y; according to the screw preparation sequence, the material is selectively supplied, and the alloy composition at the nail head is Mg-2Y-Zn-0.3Cu alloy. The...

Embodiment 2

[0035] A multi-component degradable magnesium alloy material, which is used to prepare a multi-component porous bone repair material (such as image 3 As shown), according to the actual needs, the degradable porous magnesium filling material is wrapped inside the tissue. Since the edge of the porous magnesium is the first and the longest to contact body fluids, the corrosion resistance of the edge of the material should be improved, and the inner part is the main mechanical property. The load-bearing part, so the internal structure should properly improve the mechanical properties, so that the tissue can grow smoothly and evenly degrade in the end. Therefore, the element requirements are determined as: Mg, Zn, Zr, Mn, Sr; according to the preparation sequence of the porous bone repair material, Selective feeding, the composition of the edge of the porous bone repair material is Mg-2Zn-0.5Sr alloy, a small amount of Sr element can be added to promote the growth of bone cells; th...

Embodiment 3

[0041] A degradable magnesium alloy material composed of multiple components, which is used to prepare skin staples with multiple components (such as Figure 4As shown), according to actual needs, skin staples need to have higher hardness and strength at the nail tip and higher strength and toughness at the nail leg. Better corrosion resistance is required; because the nail beam has to bear the force of the stapler hitting the nailed tissue, the strength needs to be increased, but the corrosion resistance is not high, so the determined element requirements are: Mg, Al, Zn, Zr, Mn, Nd; According to the order of staple preparation, the materials are selectively supplied. The alloy composition at the nail tip is Mg-2Zn-Nd-0.5Zr; the nail leg stem is Mg-2Zn-0.3Mn alloy, and the nail leg The joint and nail beam are Mg-3Al-Zn-0.5Nd alloy.

[0042] Its preparation method is as follows:

[0043] 1) Powder preparation: place the Mg, Al, Zn, Zr, Mn, and Nd powders required in the magn...

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Abstract

The invention discloses a degradable magnesium alloy material composed of multiple components as well as a preparation method and application thereof. The magnesium alloy material is formed by stacking a plurality of magnesium alloy layers with different component differences, wherein the component difference is that the adding elements in the magnesium alloy are different or the adding elements are the same, but the adding concentration is different. The preparation method comprises the following steps of (1) determining the type of required components, and placing the pure metal powder in different powder bins of a laser melting printer; (2) controlling the powder feeding amount of the pure metal powder of each element, and fully and mechanically mixing and then feeding the powder into apowder supply groove; and (3) carrying out melting and layered printing on the powder supplying laser in the powder supply groove to obtain the degradable magnesium alloy material with the corresponding shape and size and multiple components. The material is used as a medical implantable material to prepare bone repair or support materials. According to the degradable magnesium alloy material, mutual matching among the mechanical property, the degradation rate and the functionalization of the material is realized, and the requirements of the service environment of the biological material on the mechanical property, the degradation rate and the functionalization of the magnesium alloy are met.

Description

technical field [0001] The present invention relates to a multi-component degradable magnesium alloy material and its preparation method and application, belonging to the technical field of biomedical materials. Background technique [0002] In recent years, due to the degradability of magnesium alloy in the human body, it has become a new type of medical implantable material. Compared with traditional titanium alloy materials, degradable magnesium alloy has degradability and lower elastic modulus. (41-45GPa), compared with polymer materials, it has better mechanical properties, and at the same time has good biocompatibility, without secondary surgery, and has attracted much attention in the field of biomedical materials. Among them, in terms of medical devices, the most promising materials are the restoration and replacement of hard tissues such as teeth and joints. However, due to the low strength of magnesium alloys and the rapid corrosion of local areas during the degrad...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B22F3/105B22F7/02C22C23/02C22C23/04C22C23/06A61L27/04A61L27/58A61L31/02A61L31/14B33Y10/00B33Y80/00
CPCB22F7/02C22C23/06C22C23/04C22C23/02A61L27/04A61L27/58A61L31/022A61L31/148B33Y10/00B33Y80/00A61L2430/02B22F10/00B22F10/66B22F10/34B22F10/36B22F10/28B22F10/32Y02P10/25
Inventor 白晶张越薛烽程兆俊周健
Owner SOUTHEAST UNIV
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