Formula for treating multiple myeloma accompanied with kidney failure

Abstract

The invention provides a formula for treating multiple myeloma accompanied with kidney failure. The formula is made of the following traditional Chinese medicine raw materials: rheum officinale, radixscutellariae, astragalus roots, plantain herb, white atractylodes rhizome, white peony roots, poria cocos, rhizoma pinellinae praeparata, sodium bicarbonate, coated aldehyde oxystarch and algal polysaccharide sulfate. The traditional Chinese medicine formula has very good treatment effects on multiple myeloma accompanied with kidney failure, together with appropriate chemotherapy schemes, the formula is capable of recovering kidney functions of most patients suffering from multiple myeloma normally, a patient having intermittent dialysis can be completely released from dialysis, the dialysisfrequency of a patient depending on long-term dialysis can be reduced, and the effective rate is approximate to 100%. Treatment on protopathy multiple myeloma can be smoothly implemented, the living quality can be remarkably improved, the economic burden of individuals, families and the society can be remarkably alleviated, and the purpose that patients have long-term healthy high-quality living can be achieved. The formula is high in medicine effective rate, free of toxic or side effect, low in treatment cost, easily accepted by patients and worthy of massive popularization and application.

Description

Technical field [0001] The invention relates to the field of traditional Chinese medicine, and is a prescription for treating multiple myeloma combined with renal insufficiency. Background technique [0002] Multiple myeloma (MM) is a malignant tumor of plasma cells. The clinical manifestations are not specific, mainly hypercalcemia, impaired renal function, anemia and bone destruction, especially impaired renal function. . In MM patients at first diagnosis or at different stages of the disease course, the proportion of renal injury is 20% to 50%, of which about half of the renal function can be completely reversed, while the rest may evolve into different degrees of renal insufficiency, about 2% to 12% MM The patient requires renal replacement therapy. Once renal function cannot be completely reversed, it is often in the late stage of the disease, which not only affects the choice of late chemotherapy regimens, but also significantly shortens the patient's survival period. [0...

AI Technical Summary

Problems solved by technology

(2) AKI can be diagnosed with reference to the RIFLE criteria developed by the Acute Dialysis Quality Instruction Group (ADQI), the Acute Kidney Injury Network (AKIN) criteria, or the 2012 KDIGO AKI criteria, but the application of these criteria in MM patients still needs further prospective studies Research

Bortezomib is a synthetic highly selective 26S borate proteasome inhibitor, which can be used safely in patients with renal insufficiency and even dialysis (dialysis patients should use this drug after dialysis), but the drug is expensive and has many side effects , the clinical application is limited

[0008] MM patients with severe AKI and end-stage renal failure need dialysis treatment. Early high-flux dialysis can remove free light chains, which can help restore renal function and improve prognosis. Inconvenience

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