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Device for constructing sciatic nerve chronic constriction injury model

A sciatic nerve, chronic technology, applied in veterinary surgery, medical science, veterinary instruments, etc., can solve the problems of inability to achieve precise control of the degree of sciatic nerve compression, easy to cause slippage, poor repeatability of model construction, etc., to overcome the actual operation technology. Dependence, improve accuracy and stability, reduce error and technical difficulty

Active Publication Date: 2019-11-05
JILIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the grasp of tightness still needs to be further explored. Too tight will increase the degree of damage, and too loose will easily lead to slippage
The requirements for experimental operation are high, and the repeatability of model construction is poor
[0006] 2. For the construction of the chronic compression model of the sciatic nerve, the control of the chronic compression degree of the sciatic nerve is usually realized by the water absorption and swelling of the catgut itself, which cannot realize the precise control of the compression degree of the sciatic nerve, especially the precise control of the compression of the sciatic nerve within a specified period of time A model of oppression has yet to be developed
[0007] 3. At present, there is no model of chronic sciatic nerve compression that can adjust the deformation of the nerve compression structure in vitro, control the degree of sciatic nerve compression, the pressure and time of entrapment, and better approach the actual situation of chronic sciatic nerve compression. Nerve damage following entrapment

Method used

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  • Device for constructing sciatic nerve chronic constriction injury model
  • Device for constructing sciatic nerve chronic constriction injury model
  • Device for constructing sciatic nerve chronic constriction injury model

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] It includes a bottom support structure 1, a liftable workbench 2, a fixing device 3, an intelligent compression structure 4 and a magnetic control coil system 5, wherein the liftable workbench 2 and the magnetron coil system 5 are respectively fixed on the bottom support structure 1, and the fixing device 3 is fixedly connected to the top of the liftable workbench 2, and the intelligent compression structure 4 is located in the fixing device 3;

[0047] The liftable workbench 2 includes a fixed rod, a lifting rod, and a workbench, the fixed rod and the lifting rod are connected with locking screws, the fixed rod is fixedly connected with the base, and the lifting rod is fixedly connected with the workbench;

[0048] The fixing device 3 includes a workbench 301, a first pole 302, a locking screw 303, a second pole 304, a lower fixing plate 305, a movable shaft 306, an upper fixing plate 307, a fixing block 308, and a fixing column group 309 , the overhanging plate group ...

Embodiment 2

[0068] Smart oppression structure 4 was made by the following steps:

[0069] (1) Preparation of spiral stretchable ferrule 404

[0070](a) the average particle size is that 100 mesh magnetic powder and organic solvent are loaded into a ball mill jar and carried out ball milling, adding 250ml of organic solvent per kilogram of magnetic powder, adding the silicate dispersant of 0.2% of the weight of the magnetic powder and 2% of the weight of the magnetic powder, and ball milling Stainless steel balls with a diameter of 8mm are used, and the ball milling time is 8h. The magnetic powder is one of NdFeB, SmCo, NdFeN, SmFeN, and AlNiCo; the antioxidant is butylhydroxyanisole, dibutylhydroxytoluene, tert-butylparaphenyl A kind of in phenol; Described organic solvent is a kind of in toluene, xylene, o-xylene, Virahol;

[0071] (b) Pour out the mixed solution of organic solvent and magnetic powder in the tank, remove the ball to obtain the mixed solution of organic solvent and magn...

Embodiment 3

[0086] Smart oppression structure 4 was made by the following steps:

[0087] (1) Preparation of spiral stretchable ferrule 404

[0088] (a) the average particle size is that 200 mesh magnetic powder and organic solvent are loaded into ball milling jar and carry out ball milling, every kilogram of magnetic powder adds organic solvent 500ml, adds the silicate dispersant of the antioxidant of 0.1% of magnetic powder weight and 1% of magnetic powder weight, ball milling Stainless steel balls with a diameter of 12mm are used, and the ball milling time is 10h; the magnetic powder is one of NdFeB, SmCo, NdFeN, SmFeN, and AlNiCo; the antioxidant is butylhydroxyanisole , a kind of in dibutyl hydroxytoluene, tert-butyl hydroquinone; Described organic solvent is a kind of in toluene, xylene, o-xylene, isopropanol;

[0089] (b) Pour out the mixed liquid of organic solvent and magnetic powder in the tank, remove the ball to obtain the mixed liquid of organic solvent and magnetic powder, ...

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Abstract

The invention relates to a device for constructing a sciatic nerve chronic constriction injury model, and belongs to the fields of polymer materials and biomedical devices. A liftable work table and amagnetic control coil system are fixed on a bottom support structure; a fixed device is fixedly connected on the top of the liftable work table; an intelligent constriction structure is located in the fixed device. With structure design of a composite ink with magnetic response performance and specific magnetic domain distribution, a spiral stretchable clamp sleeve is remotely excited to producecontrollable deformation, so the clamp sleeve produces axial contraction; by control of the magnetic control coil system, the stretchable clamp sleeve can produce axial contraction in different degrees, meet the needs of different degrees of multiple deformation required by the chronic constriction model, and improve the accuracy and stability of the model construction.

Description

technical field [0001] The invention relates to the fields of polymer materials and biomedical devices, in particular to a device for constructing a chronic compression model of the sciatic nerve. Background technique [0002] Peripheral nerve injury is clinically more common, accounting for about 1.5% to 4% of all trauma. It can lead to severe limb dysfunction, mainly movement disorders, sensory disorders and nutritional disorders, and has a high disability rate. The pathogenesis of peripheral nerve entrapment is relatively complex, which may be related to multiple factors such as physical factors, chemical factors, and biological factors. Therefore, this is an urgent problem to be solved in clinical treatment, and it is also a hot issue in the field of neurobiology. Depending on the location and degree of peripheral nerve entrapment, the resulting clinical symptoms are also different, and due to the particularity of peripheral nerve anatomy and function, an accurate and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61D1/00
CPCA61D1/00
Inventor 崔树森吴文征柳溪林王培培
Owner JILIN UNIV
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