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Method for extracting polyphenols from diaphragma juglandis fructus

A technology of walnut distraction wood and distraction wood, which is applied in the directions of medical preparations containing active ingredients, pharmaceutical formulations, non-central pain relievers, etc. It can improve the utilization rate of walnuts, reduce the loss of polyphenols, and optimize the conditions easily.

Inactive Publication Date: 2019-10-08
HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The traditional polyphenol extraction mostly adopts solvent extraction method. The cell wall of fenugreek is thick, and polyphenols are not easy to release. The extraction requires high temperature conditions and takes a long time.
Because the higher the temperature in the process, the easier it is to release polyphenols, but too high temperature will break the double bond in the polyphenol ring, causing the degradation of polyphenols, destroying the properties of polyphenols, thereby affecting the extraction rate of polyphenols, so In the prior art, the temperature cannot be effectively controlled, which not only ensures the release of polyphenols, but also effectively prevents the degradation of polyphenols
[0004] The extraction of polyphenols in the distracted wood requires wall-breaking pretreatment. The traditional wall-breaking methods include the following: (1) The wall-breaking method of the spherical membrane machine is relatively old, and the wall-breaking rate is low and the effect is poor. (2) chemical reagent method, which will destroy the extracted substance and change the properties of the substance; (3) biological enzymatic hydrolysis method, which is easy to cause product inhibition, and the high price of lysozyme limits large-scale utilization; ( 4) Ultrafine pulverization method, which is the most commonly used wall-breaking technology at present. It uses shear force to pulverize the substance. The disadvantage is that the pulverization is uneven, and it needs to be operated under high temperature conditions, which will make the double bonds in the polyphenol ring Fracture, causing the degradation of polyphenols, thus affecting the extraction rate of polyphenols

Method used

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  • Method for extracting polyphenols from diaphragma juglandis fructus

Examples

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Effect test

Embodiment 1

[0029] Embodiment 1 A kind of method of extracting polyphenols in walnut split wood

[0030] This embodiment is carried out in the following steps:

[0031] 1. Pretreatment

[0032] Select the split wood from the walnut produced in Lincheng County, Xingtai City, Hebei Province, crush it through a 200-mesh sieve, input it into the cavity of the extruder, and extrude it at a low temperature to obtain the split wood powder A1. The puffing conditions are as follows: the puffing sleeve temperature is 70°C, the screw speed is 200r / min, and the membrane pore diameter is 8nm. By adjusting the force between the cavity, the screw and the material, the pressure inside the cavity is gradually increased. After that, when the material is released, the pressure drops instantaneously, the moisture in the material evaporates instantaneously, and the structure changes. Through low temperature and high pressure expansion, the active substances in the cells can be released better, and it is ap...

Embodiment 2-8

[0042] Embodiment 2-8 The method for extracting polyphenols in walnut split wood

[0043] Embodiment 2-8 is respectively a kind of method for extracting polyphenols in walnut split wood, and their extraction steps are all the same as in Example 1, only the operating parameters in the extraction process are different, and the specific operating parameters are as shown in Table 1:

[0044] Table 1

[0045]

Embodiment 9

[0046]Example 9 Extraction effect of the method for extracting polyphenols in walnuts

[0047] This embodiment is the determination of the extraction effect of the method used to extract polyphenols in walnuts in Examples 1-8.

[0048] Use the Folin-Ciocalteu method to measure the polyphenol content in the extract, and the specific detection steps are as follows:

[0049] Prepare gallic acid standard solution, absorb 1.0mL of standard solution of each concentration, add 3mL of 7.5% sodium carbonate solution and 1mL of Folin’s phenol reagent for color development, add distilled water to make up to 10mL, shake well, and place in the dark for 2h , Measure the absorbance value of each standard solution at a wavelength of 765nm. Draw a standard curve between the measured absorbance y and the corresponding gallic acid concentration x, and the regression equation is: y=13.24x+0.0833, R 2 =0.997.

[0050] After diluting the lyophilized powder of fenxin in Examples 1-8 to be the ext...

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Abstract

The invention discloses a method for extracting polyphenols from diaphragma juglandis fructus, which comprises the steps of pretreatment, extraction, and purifying. The method introduces a low-temperature extrusion puffing technology and a low-temperature and high-pressure homogenization extraction technology in a extraction process of a traditional solvent extraction method, by adjusting the pressure to lower the extraction temperature, the polyphenol release efficiency is improved, loss is reduced, so that the efficiency of polyphenol extraction is increased. The method is suitable for extracting polyphenols from diaphragma juglandis fructus.

Description

technical field [0001] The invention belongs to a technology for extracting active ingredients from natural plant fruits, in particular to a method for extracting polyphenols from walnut and heartwood. Background technique [0002] Centerwood is the woody septum inside the walnut pit, usually accounting for 4-5% of the walnut's mass. Both traditional medicine and modern research have shown that distracting wood has good medicinal value, and can be used to treat diseases such as invigorating the spleen and strengthening the kidney, diuresis and clearing away heat, treating insomnia and amnesia, gonorrhea, hematuria, and diarrhea due to summer heat. Fenxin wood contains functional phenolic substances such as gallic acid, ethyl gallate, and quercetin, which have various health functions such as anti-inflammatory, anti-oxidation, antibacterial, and antiviral. However, there are few studies on the extraction of functional components in S. sativa, and even fewer reports on the ex...

Claims

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Application Information

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IPC IPC(8): A61K36/52A61P29/00A61P39/06A61P31/04A61P31/12A61K131/00
CPCA61K36/52A61K2236/333A61K2236/53A61K2236/55A61P29/00A61P31/04A61P31/12A61P39/06
Inventor 高山牟德华王嘉佳
Owner HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY
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