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Tartary buckwheat flavone dry powder and use of tartary buckwheat flavone dry powder in preparing health care products with auxiliary hypoglycemic function

A technology of tartary buckwheat flavonoids and health products, which is applied in the field of food processing, can solve the problems of low content of tartary buckwheat flavonoids and low utilization rate of raw materials, and achieve the effects of small toxic and side effects, mild effect and great market potential

Pending Publication Date: 2019-10-08
SHANGHAI JIAOTONG UNIV SCHOOL OF MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The main purpose of the present invention is to solve the problems of low tartary buckwheat flavonoid content and low raw material utilization rate in the existing tartary buckwheat processed products, and provide a tartary buckwheat flavonoid dry powder with a high extraction rate of tartary buckwheat flavonoids. Raw materials, according to the processing characteristics of different parts of raw materials, adopt different processing methods to improve the extraction rate of tartary buckwheat flavonoids and the utilization rate of raw materials

Method used

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  • Tartary buckwheat flavone dry powder and use of tartary buckwheat flavone dry powder in preparing health care products with auxiliary hypoglycemic function
  • Tartary buckwheat flavone dry powder and use of tartary buckwheat flavone dry powder in preparing health care products with auxiliary hypoglycemic function
  • Tartary buckwheat flavone dry powder and use of tartary buckwheat flavone dry powder in preparing health care products with auxiliary hypoglycemic function

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0093] Example 1 Hyperglycemia model animal hypoglycemic experiment

[0094] The hyperglycemia model animals were selected and grouped according to the blood glucose level after fasting for 3 to 5 hours, and a model control group and 3 dose groups were randomly selected (the difference between the groups was not greater than 1.1 mmol / L). The dose group was given different concentrations of test samples, and the model control group was given solvent. For 30 consecutive days, the fasting blood glucose was measured (fasting was the same as before the experiment), and the blood glucose and blood glucose reduction percentages of animals in each group were compared.

[0095]

Embodiment 2

[0096] Example 2 Glucose tolerance experiment of hyperglycemia model animals

[0097] Dose grouping and test sample administration time are the same as 1.4.2. Animals in each group were fasted for 3 to 5 hours, and blood glucose levels were measured before glucose or medical starch was given (that is, 0 hours). The dose group was given different concentrations of test samples, and the model control group was given the same volume of solvent. After 15 to 20 minutes, each group Oral administration of glucose 2.0g / kg BW or medical starch 3-5g / kg BW, measure the blood glucose values ​​of each group at 0.5 and 2 hours after glucose administration or 1 and 2 hours after administration of medical starch, observe the model control group and Changes in the blood glucose value and the area under the blood glucose curve at each time point (0, 0.5, 2 hours) after the test sample group was given glucose or medical starch.

[0098]

Embodiment 3

[0099] Embodiment 3 Normal group mice body weight, blood sugar and glucose tolerance test data statistics

[0100] Table 10: Effect of Black Tartary Buckwheat Hypoglycemic Capsules on Body Weight of Normal Mice (n±s)

[0101] group Before gavage 2 weeks after gavage 3 weeks after gavage 4 weeks after gavage normal blank group 36.05±3.56 36.40±4.07 38.30±4.49 39.70±5.02 normal high dose group 34.49±2.63 34.66±2.38 36.82±2.69 37.42±2.58

[0102] It can be seen from Table 10 that, compared with the blank control group, there was no significant difference in the body weight of the normal mouse high-dose group in the early stage, middle stage and late stage of the experiment (P>0.05).

[0103] Table 11: Effect of Black Tartary Buckwheat Hypoglycemic Capsules on Fasting Blood Glucose in Normal Mice (n±s)

[0104]

[0105] It can be seen from Table 11 that, compared with the blank control group, there was no significant difference in fastin...

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Abstract

The invention discloses tartary buckwheat flavone dry powder and use of the tartary buckwheat flavone dry powder in preparing health care products with the auxiliary hypoglycemic function. According to the tartary buckwheat flavone dry powder, after screening, cleaning, drying and shelling, black buckwheat is ground and screened to be divided into raw core powder and raw skin layer powder, and theraw core powder is baked at 160~220 DEG C for 20~40 minutes to obtain cooked core powder; and the raw skin layer powder and the cooked core powder are weighed according to the mass ratio of 9 to 11,and mixed with edible alcohol, reflux extraction and vaccum filtration are conducted, and a tartary buckwheat flavone extracting solution is obtained, the tartary buckwheat flavone dry powder is obtained through vaccum concentration, drying, comminution and screening in sequence, the obtained tartary buckwheat flavone dry power is used as active components of the care products with the auxiliary hypoglycemic function, and effective use dosages are 0.001~0.01 g / kg.bw. According to the tartary buckwheat flavone dry powder and the use of the tartary buckwheat flavone dry powder in preparing the health care products with the auxiliary hypoglycemic function, when the extraction rate and the raw material utilization rate of the tartary buckwheat flavone are improved, the tartary buckwheat flavone is used for auxiliary hypoglycemic of patients with high blood sugar or diabetes mellitus, the effect is gentle, side effects are small, and market potentials are great.

Description

technical field [0001] The invention belongs to the field of food (health food) processing, and in particular relates to tartary buckwheat flavonoid dry powder and its use in preparing health products with the function of assisting in lowering blood sugar. Background technique [0002] Tartary buckwheat belongs to Polygonaceae (Polygonacea) Buckwheat (Fagopyrum Mill.), scientific name Tartary buckwheat (F.tataricum), contains tartary buckwheat flavonoids, buckwheat sugar alcohol, D-chiro-inositol, polyphenols, sterols, resistant starch , peptides and other bioactive molecules with hypoglycemic effect, among which tartary buckwheat flavonoids, buckwheat sugar alcohol and D-chiroinositol have better hypoglycemic effects, which have been widely studied and reported. Tartary buckwheat is rich in flavonoids, and flavonoids account for 3.05% of the dry weight of tartary buckwheat grains. Rutin is the main component of tartary buckwheat flavonoids, accounting for about 70% of the t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/105A61K36/70A61P3/10
CPCA23L33/105A61K36/70A61P3/10A23V2002/00A23V2200/328A23V2250/1586A23V2250/2116A23V2250/51084A23V2250/082A23V2300/10A23V2300/14A23V2300/50
Inventor 王慧葛瑞宏
Owner SHANGHAI JIAOTONG UNIV SCHOOL OF MEDICINE
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