Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Cancer treatment curcumin compound preparation

A technology of compound preparation and curcumin, which is applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, ether/acetal active ingredients, etc., can solve the problems of easy recurrence, detection of recurrence, high cost of targeted therapy, etc., to achieve No toxic side effects, high safety effect

Active Publication Date: 2019-02-19
朱理查德澄朗
View PDF5 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] 1) Because of its clinical application, conventional chemotherapy can only relieve cancer, but cannot cure cancer, and because it kills cancer cells and normal cells at the same time, it will cause serious adverse reactions during treatment, such as bone marrow function suppression, nausea, Gastrointestinal adverse reactions such as diarrhea and vomiting; reduced safety of the drug, and easy relapse after treatment due to inability to kill cancer stem cells
The cost of conventional chemotherapy generally costs tens of thousands to hundreds of thousands of yuan for a course of treatment;
[0006] 2) Targeted therapy: its curative effect is slightly better than conventional chemotherapy, but because it can only target 1-2 targets, it is difficult to cure cancer, and its advantage is that it can only prolong the life of patients by an average of several months compared with chemotherapy
In addition, although immunotherapy represented by PD-1 (programmed cell death-1) and PD-L1 (programmed death ligand-1) antibodies has good curative effect, it is limited to about 20% of cancer patients, so Its application is relatively limited, and the cost of targeted therapy is relatively high. Generally, a course of treatment also costs tens to hundreds of thousands of yuan;
[0007] 3) Chimeric antigen receptor T cell immunotherapy (CAR-T); although it is very popular because of its short-term curative effect, it also has its limitations, and recurrence can still be found if long-term follow-up
[0012] Cancer, like AIDS, is a very difficult disease to treat, and the treatment of difficult and miscellaneous diseases often requires extraordinary means and innovative breakthrough methods, relying only on traditional cancer treatment methods, and using one or two anticancer chemotherapy drugs. Most cannot effectively control or cure cancer

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Cancer treatment curcumin compound preparation
  • Cancer treatment curcumin compound preparation
  • Cancer treatment curcumin compound preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0094] Present embodiment provides a kind of curcumin compound preparation for treating cancer, and raw material component comprises:

[0095] Curcumin 1μg, pterostilbene 1μg.

Embodiment 2

[0097] Present embodiment provides a kind of curcumin compound preparation for treating cancer, and raw material component comprises:

[0098] Curcumin 1 μg, δ-tocotrienol 10 μg.

Embodiment 3

[0100] Present embodiment provides a kind of curcumin compound preparation for treating cancer, and raw material component comprises:

[0101] Pterostilbene 1 μg, δ-tocotrienol 10 μg.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a cancer treatment curcumin compound preparation. According to the cancer treatment curcumin compound preparation, the three adverse effect-free components of curcumin, pterostilbene and delta-tocotrienol 3 serve as raw materials and are compounded at an appropriate ratio to achieve synergistic effects, thereby combining the number of anti-cancer target points and anticancer spectrum and significantly increasing the anticancer effects. Due to the fact that the curcumin can kill cancer stem cells, compared with normal chemotherapy which cannot kill the cancer stem cells, the cancer treatment curcumin compound preparation can significantly reduce cancer recurrence. The cancer treatment curcumin compound preparation is non-toxic to human body and can avoid adverse effects when applied with large dose. Meanwhile, the cancer treatment curcumin compound preparation can reduce the estimated treatment expense by a half or more compared with conventional chemotherapeutic drugs and is far lower in cost than CAR-T (chimeric antigen receptor T-cell immunotherapy, thereby having a broad application prospect in the field of cancer treatment.

Description

technical field [0001] The invention belongs to the technical field of medicines, in particular to a curcumin compound preparation for treating cancer. Background technique [0002] Cancer is a general term for a variety of diseases that can affect any part of the body. Other terms used are malignant tumor and neoplasm. A defining feature of cancer is the rapid production of abnormal cells that grow beyond their usual boundaries and can invade adjacent parts of the body and spread to other organs. This process is called metastasis, and metastasis is the leading cause of death from cancer. Cancer is currently one of the leading causes of death worldwide. WHO estimates that without intervention, 84 million people will die from cancer between 2005 and 2015. [0003] Cancer cells have the ability to grow and spread uncontrollably, it can affect almost any part of the body, and often invades surrounding tissue and can metastasize to other sites. Cancer is a leading cause of d...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/12A61K31/09A61K31/355A61P35/00
CPCA61K31/09A61K31/12A61K31/355A61K2300/00
Inventor 朱理查德澄朗
Owner 朱理查德澄朗
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products